Nutrition and Metabolic Prehabilitation in HSCT Patients UK and ROI. BSBMT Multi-centre Survey.

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

• Ages 18 years and older
• All sexes
• Healthy volunteers accepted
• Adult, Older adult

Study population: Health care professionals working within an adult HSCT setting

Trial locations and contacts

1 site in 1 country.

About this study

Official title: Exploration of Nutrition and Metabolic Prehabilitation Practices for Haematopoietic Stem Cell Transplant (HSCT) in UK and ROI Transplant Centres: A BSBMT Multi-centre Survey

Conditions

Haematological Malignancy, Bone Marrow Transplant Complications, Stem Cell Transplant Complications, Nutrition Aspect of Cancer, Nutritional and Metabolic Disease, Exercise Interventions

Being tested

Non validated Survey

Keywords

nutrition, metabolism, exercise, bone marrow transplant, stem cell transplant, autologous transplant, allogeneic transplant, prehabilitation

Medical subject headings

Hematologic Neoplasms, Metabolic Diseases, Motor Activity

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

• Non validated SurveyOther

  Overall inclusion of metabolic and nutritional parameters in prehabilitation practices will be assessed as the proportion of each parameter conducted from the mandatory queries presents as yes/no/unsure responses for each centre. Intervention or process details for included parameters will be described based on the response variable. The survey presents 4 question formats; free text (thematic qualitative analysis), 5 and 6 point likert scales (proportional response), categorical data (proportional response) and yes/no/unsure response sets (Binary response (no and unsure - grouped). All categorical data versions are parameter dependent and response variables can be requested from the research team.

What is being measured

The primary outcome is the main question the study is designed to answer.

1. To understand the routine screening, assessment and management practices of nutritional and metabolic parameters prior to haematopoeitic stem cell transplantation in UK centres

   full survey completion: see parameters below

   Measured: Aug 20- March22

2. Differences in frequency of glycaemic screening prior to HSCT across UK and ROI HSCT centres and between health professionals

   1. Glycaemic screening will be assessed by 2 responses: How often would you measure blood glucose and urinary glucose prior to HSCT? (likert scale - Always, often, sometimes, rarely, never)

   Measured: Aug 20-March22

3. Differences in frequency of assessments of lipid profile screening prior to HSCT across UK and ROI HSCT centres and between health professionals

   1. Lipid parameters: How often would you measure blood glucose and urinary glucose prior to HSCT? (likert scale - Always, often, sometimes, rarely, never)

   Measured: Aug 20-March22

4. Differences in frequency of assessments of liver and renal function prior to HSCT across UK and ROI HSCT centres and between health professionals

   1. Liver and renal function screening frequency will be asked: 1. How often would you measure liver/kidney function as blood samples prior to HSCT? (likert scale - Always, often, sometimes, rarely, never); 2. How often would you measure liver/kidney function using a scan prior to HSCT? (likert scale - Always, often, sometimes, rarely, never)

   Measured: Aug 20-March22

5. Differences in nutritional screening and assessment practices done prior to HSCT across UK and ROI HSCT centres and between health professionals

   1. Nutritional screening and assessment: Routine inclusion of nutritional screening and assessment practices prior to HSCT will be assessed using 4 mandatory questions, 3 - yes/no/unsure and 1 categorical question. Practical details of strategies of assessment and measurement will be assessed using 5 categorical questions and 6 free text questions.

   Measured: Aug 20-March22

6. Differences in body composition assessments given prior to HSCT across UK and ROI HSCT centres and between health professionals

   1. Assessment of body composition: Routine inclusion of body composition assessment prior to HSCT will be assessed using 2 mandatory questions, 1 - yes/no/unsure and 1 categorical question. Practical details of strategies of assessment and measurement will be assessed using 2 categorical questions and 3 free text questions.

   Measured: Aug 20-March22

7. Differences in dietary advice given prior to HSCT across UK and ROI HSCT centres and between health professionals

   1. Dietary advice: Routine inclusion of dietary advice prior to HSCT will be assessed using 3 mandatory questions, 1 - yes/no/unsure and 2 - five point likert scales (definitely = 4, very probably = 3, probably=2, probably not = 1, definitely not =0). Practical details of types of dietary advice and strategies for implementation will be assessed using 2 categorical questions, 2 free text questions and 3 - six point likert scaled consensus statements (Always= 5, very frequently = 4, occasionally = 3, rarely = 2, very rarely = 1, never = 0)

   Measured: Aug 20-March22

8. Differences in enteral feeding practices prior to HSCT across UK and ROI HSCT centres and between health professionals

   1. Enteral feeding: Routine inclusion of enteral feeding prior to HSCT will be assessed using 2 mandatory questions, 1 - categorical. Practical details of types of enteral feeding tubes 2 questions (1 - categorical questions, 1 free text)

   Measured: Aug 20-March22

9. Differences in specialist dietary advice given prior to HSCT across UK and ROI HSCT centres and between health professionals

   1. Micronutrient supplementation: Routine inclusion of micronutrient advice prior to HSCT will be assessed using 1 mandatory question, yes/no/unsure format. Practical details of micronutrient supplementation practices using 1 categorical questions and 1 free text question.

   Measured: Aug 20-March22

10. Differences in physical assessment, advice and delivery prior to HSCT across UK and ROI HSCT centres and between health professionals

    1. Exercise: As part of routine practice how often do patients receive exercise advice prior to HSCT? (likert response: Always, often, sometimes, rarely, never); As part of "routine practice" how often do your patients have their activity levels measured prior to HSCT i.e. questionnaire or physical assessment? response: Always, often, sometimes, rarely, never); and 2 multi select questions to determine professionals delivering care.

    Measured: Aug 20-March22

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

1. First posted29 Apr 2022
2. Study start1 Aug 2020
3. Primary completion1 Mar 2022
4. Study completion1 Mar 2022

Resources

• Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
• Other trials for Haematological MalignancyStudies of the same condition, open and under way.
• What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.