BurnoutReTA-modelNCT05314530
The ReTA-model: Rehabilitation Trail for Workers on Long-term Sick Leave in the Healthcare Sector
A study testing ReTA-model in people with Burnout, run by Karolinska Institutet at 1 site in Sweden.
Trial summary
The ReTA-model is a rehabilitation model for return to work after long-term sickness absence (LTSA) due to stress or burnout. The ReTA-model will be validated in this trial among nurses and physicians currently in LTSA. Read more about this study
- Who is it for?
- Any age
- Conditions the study is for
- Burnout
- What is being tested?
- ReTA-model
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 64 participants
- Where
- 1 siteSweden
- Study dates
- 1 Mar 2022to Sep 2023
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Who may be able to join
- currently on sick leave for burnout
- employed in the Swedish healthcare services as a nurse or as a physician
Who cannot join
- -
Trial locations and contacts
1 site in 1 country.
Åke Nygren, MD contact
Sweden1 site, 1 recruiting
- Recruiting
Karolinska Institutet
Stockholm, Outside U.S. and Canada, 171 77
Emma Hagqvist, Phd, +46730526602, emma.hagqvist@ki.se
About this study
Official title: Validation of the ReTA-model: Rehabilitation Trail for Workers on Long-term Sick Leave in the Healthcare
The ReTA-model is a rehabilitation model for return to work after long-term sickness absence (LTSA) due to stress or burnout. The ReTA-model will be validated in this trial among nurses and physicians currently in LTSA. The ReTA-model includes a three-week treatment with exercise, individual and collegial talks with psychology and lecturing. The control group will receive conventional rehabilitation from regular care.
Read the detailed description
The ReTA-model is a rehabilitation model for return to work after long-term sickness absence (LTSA) due to stress or burnout. The ReTA-model will be validated in this trial among nurses and physicians currently in LTSA. The ReTA-model includes a three-week treatment with exercise, individual and collegial talks with psychology and lecturing. The control group will receive conventional rehabilitation from regular care.
- Conditions
- Burnout
- Being tested
- ReTA-model
- Keywords
- Healthcare, Burnout, Stress, Return to work, Intervention
- Medical subject headings
- Burnout, Psychological
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
ReTA-modelBehavioural
Validating the rehabilitation model ReTA
| Study group | Role | What they receive |
|---|---|---|
| Intervention group | Experimental | Will receive a rehabilitation intervention Receives: Behavioral: ReTA-model |
| Controll | Active comparator | Will receive conventional rehabilitation Receives: Behavioral: ReTA-model |
What is being measured
The primary outcome is the main question the study is designed to answer.
Return to work
At work part or full-time compare to no return to work
Measured: 12 months
Karolinska Exhaustion Disorder Scale KEDS
Decreased points in the KEDS scale 1-19, qith higher scores reflecting greater exhaustion severity.
Measured: 12 months
Symptom Checklist - 6
Decreased points on the SCL-6 scale, with a higher number reflecting depression.
Measured: 12 months
Montgomery Åsberg Depression Rating Scale
Decreased points in the MADRAS scale with score ranging from 0 to 60, with higher scores reflecting greater depression severity.
Measured: 12 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 Apr 2022
- Study start1 Mar 2022
- Primary completionApr 2023 (estimated)
- Study completionSep 2023 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for BurnoutStudies of the same condition, open and under way.
- More trials run by Karolinska InstitutetThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 64 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Karolinska Institutet
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Emma Hagqvist, Karolinska Institutet
- Investigators
- Emma Hagqvist, Principal investigator, Karolinska Institutet
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05314530
- Sponsor's protocol ID
- ReTA-model
- Acronym
- ReTA-model
- Status last verified
- Mar 2022
- First submitted
- 30 Mar 2022
- Last updated
- 6 Apr 2022
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Thunqvist E, Nygren A, Lofman B, Parker D, Brulin E. Assessing the Effect of a Rehabilitation Intervention on Exhaustion Disorders, Depression, and Return to Work: A Randomized Controlled Trial. J Occup Rehabil. 2025 Dec 13. doi: 10.1007/s10926-025-10350-y. Online ahead of print.
PubMed 41389236
Study at a glance
From the registry record, last updated by the sponsor on 6 Apr 2022. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Validation of the ReTA-model: Rehabilitation Trail for Workers on Long-term Sick Leave in the Healthcare
- ClinicalTrials.gov ID
- NCT05314530
- Acronym / sponsor ID
- ReTA-model / ReTA-model
- Conditions
- Burnout
- Keywords
- Healthcare, Burnout, Stress, Return to work, Intervention
- Study type
- Interventional
- Recruitment status
- Unknown status
- Enrolment
- 64 participants (estimated)
- Lead sponsor
- Karolinska InstitutetUniversity, hospital or other
- Study start
- 1 Mar 2022 (actual)
- Primary completion
- Apr 2023 (estimated)
- Study completion
- Sep 2023 (estimated)
- First posted
- 6 Apr 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The ReTA-model is a rehabilitation model for return to work after long-term sickness absence (LTSA) due to stress or burnout. The ReTA-model will be validated in this trial among nurses and physicians currently in LTSA. The ReTA-model includes a three-week treatment with exercise, individual and collegial talks with psychology and lecturing. The control group will receive conventional rehabilitation from regular care.
Detailed description
The ReTA-model is a rehabilitation model for return to work after long-term sickness absence (LTSA) due to stress or burnout. The ReTA-model will be validated in this trial among nurses and physicians currently in LTSA. The ReTA-model includes a three-week treatment with exercise, individual and collegial talks with psychology and lecturing. The control group will receive conventional rehabilitation from regular care.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Intervention group | Experimental | Behavioral: ReTA-modelWill receive a rehabilitation intervention |
| Controll | Active comparator | Behavioral: ReTA-modelWill receive conventional rehabilitation |
Who may qualify
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
Key inclusion criteria (2 listed)
- currently on sick leave for burnout
- employed in the Swedish healthcare services as a nurse or as a physician
Key exclusion criteria (1 listed)
- -
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| ReTA-modelValidating the rehabilitation model ReTA | Behavioural | Controll, Intervention group |
Primary outcome
Return to work
Time frame: 12 months
At work part or full-time compare to no return to work
Karolinska Exhaustion Disorder Scale KEDS
Time frame: 12 months
Decreased points in the KEDS scale 1-19, qith higher scores reflecting greater exhaustion severity.
Symptom Checklist - 6
Time frame: 12 months
Decreased points on the SCL-6 scale, with a higher number reflecting depression.
Montgomery Åsberg Depression Rating Scale
Time frame: 12 months
Decreased points in the MADRAS scale with score ranging from 0 to 60, with higher scores reflecting greater depression severity.
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Apr 2022.
- Derived from this study: PubMed 41389236Thunqvist E, Nygren A, Lofman B, Parker D, Brulin E. Assessing the Effect of a Rehabilitation Intervention on Exhaustion Disorders, Depression, and Return to Work: A Randomized Controlled Trial. J Occup Rehabil. 2025 Dec 13. doi: 10.1007/s10926-025-10350-y. Online ahead of print.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Åke Nygren, MD contact
Emma Hagqvist principal investigator
Karolinska Institutet
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing ReTA-model in people with Burnout, run by Karolinska Institutet at 1 site in Sweden.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 6 Apr 2022. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Sweden. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
Contact Emma Hagqvist, PhD (+46730526602, emma.hagqvist@ki.se), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Return to work (time frame: 12 months). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT05314530, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Apr 2022.