Premature Myocardial Infarction in Young Egyptian PatientsSIRT1NCT05160844
SIRT1 Gene Polymorphism With Premature Myocardial Infarction in Young Egyptian Patients
An observational study of Premature Myocardial Infarction in Young Egyptian Patients, run by Sohag University at 1 site in Egypt.
Trial summary
This is an observertional study aimed at Study the association of SIRT1(rs7069102 ) Gene polymorphism with premature myocardial infarction in young Egyptian patients Read more about this study
- Who is it for?
- Ages 18 to 40 yearsHealthy volunteers can take part
- Conditions the study is for
- Premature Myocardial Infarction in Young Egyptian Patients
- How many people
- 280 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Sep 2021to 1 Jan 2024
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 40 years
- All sexes
- Healthy volunteers accepted
- Adult
Study population: young egyptian patients under 40 years of age presented with recent MI admitted to CCU at sohag university hospital.
Who may be able to join
- All patient with recent MI admitted to Sohag University Hospital , CCU under 40 years
Who cannot join
- patients above 40 year old.
- Patients with malignancies, major trauma or surgery in the previous six months, and acute or chronic infectious disease
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Association of SIRT1(rs7069102 ) Gene Polymorphism With Premature Myocardial Infarction in Young Egyptian Patients
This is an observertional study aimed at Study the association of SIRT1(rs7069102 ) Gene polymorphism with premature myocardial infarction in young Egyptian patients
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Diseased | young Egyptian patients with premature myocardial infarction | |
| Control | healthy young Egyptians |
What is being measured
The primary outcome is the main question the study is designed to answer.
Endothelial nitric oxide synthase level
detect the serum level of Endothelial nitric oxide synthase by ELIZA in nanogram per millilitre (ng/ml)
Measured: 6 months
SIRT1 Genotyping
whether homgenetic or heterogenetic
Measured: 6 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 Dec 2021
- Study start1 Sep 2021
- Primary completion1 Sep 2023
- Study completion1 Jan 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Premature Myocardial Infarction in Young Egyptian PatientsStudies of the same condition, open and under way.
- More trials run by Sohag UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Enrolment
- 280 participants (actual)
Sponsor and investigators
- Lead sponsor
- Sohag University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Amera Morad Foad, Sohag University
- Investigators
- Amera Morad Foad hamdy, lecturer, Principal investigator, Sohag faculty of medicine
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05160844
- Sponsor's protocol ID
- Soh-Med-21-11-33
- Acronym
- SIRT1
- Status last verified
- Jul 2024
- First submitted
- 6 Dec 2021
- Last updated
- 9 Jul 2024
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 9 Jul 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Association of SIRT1(rs7069102 ) Gene Polymorphism With Premature Myocardial Infarction in Young Egyptian Patients
- ClinicalTrials.gov ID
- NCT05160844
- Acronym / sponsor ID
- SIRT1 / Soh-Med-21-11-33
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 280 participants (actual)
- Lead sponsor
- Sohag UniversityUniversity, hospital or other
- Study start
- 1 Sep 2021 (actual)
- Primary completion
- 1 Sep 2023 (actual)
- Study completion
- 1 Jan 2024 (actual)
- First posted
- 16 Dec 2021 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This is an observertional study aimed at Study the association of SIRT1(rs7069102 ) Gene polymorphism with premature myocardial infarction in young Egyptian patients
Study design
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Diseased | – | –young Egyptian patients with premature myocardial infarction |
| Control | – | –healthy young Egyptians |
Who may qualify
- Ages
- 18 to 40 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
- Study population
- young egyptian patients under 40 years of age presented with recent MI admitted to CCU at sohag university hospital.
Key inclusion criteria (1 listed)
- All patient with recent MI admitted to Sohag University Hospital , CCU under 40 years
Key exclusion criteria (2 listed)
- patients above 40 year old.
- Patients with malignancies, major trauma or surgery in the previous six months, and acute or chronic infectious disease
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Endothelial nitric oxide synthase level
Time frame: 6 months
detect the serum level of Endothelial nitric oxide synthase by ELIZA in nanogram per millilitre (ng/ml)
SIRT1 Genotyping
Time frame: 6 months
whether homgenetic or heterogenetic
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 9 Jul 2024.
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Amera Morad Foad hamdy, lecturer principal investigator
Sohag faculty of medicine
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Premature Myocardial Infarction in Young Egyptian Patients, run by Sohag University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 9 Jul 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Endothelial nitric oxide synthase level (time frame: 6 months). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Jul 2024.