HypertensionNCT05048147
Community Mobilization for Improved Clean Cookstove Uptake, Household Air Pollution Reduction, and Hypertension Prevention
A study testing Community Mobilization in people with Hypertension, run by NYU Langone Health at 4 sites in 2 countries.
Trial summary
Using a focused implementation research framework, the EPIS (Exploration, Preparation, Implementation and Sustainment) model in a type-2 hybrid design, the study will be conducted in 3 phases: 1) A pre-implementation phase that will use the Exploration and Preparation domains of EPIS to: a) explore barriers and… Read more about this study
- Who is it for?
- Ages 18 to 85 years
- Conditions the study is for
- Hypertension
- What is being tested?
- Community Mobilization
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 1,280 participants
- Where
- 4 sitesin 2 countries
- Study dates
- 11 Apr 2023to Jun 2026
- Phase
- Interventional
- Are there results?
- Yes, posted in the registrySummary in the doctors' view
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 85 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Primary adult must be a female cook;
- Must not have a paid housemaid;
- Family size must be a minimum of 2 and no more than 7 members;
- Family must use Kerosene, charcoal, LPG, or firewood as primary cooking fuel;
- The person spoken to at enrollment must be the home key decision maker;
- Must have no plans for relocation in the next year.
Who cannot join
- Does not meet the inclusion criteria
Trial locations and contacts
4 sites in 2 countries.
4 sites in 2 countries
United States2 sites
University of Chicago
Chicago, Illinois, 60637
NYU Langone Health
New York, New York, 10016
Nigeria2 sites
University of Ibadan
Ibadan, 200001
Lagos State University College of Medicine
Lagos, 101233
About this study
Using a focused implementation research framework, the EPIS (Exploration, Preparation, Implementation and Sustainment) model in a type-2 hybrid design, the study will be conducted in 3 phases: 1) A pre-implementation phase that will use the Exploration and Preparation domains of EPIS to: a) explore barriers and facilitators of Clean Fuel- Clean- Stove (CF-CS) use, and b) develop a culturally-tailored CM strategy for CF-CS use; 2) An Implementation phase that will use the Implementation domain of EPIS to compare in a cluster RCT of 32 peri-urban communities (640 households), the effect of CM vs. a self-directed condition (i.e. receipt of information on CF-CS use without CM) on adoption of CF-CS use; and systolic BP reduction; 3) A post-implementation phase that will use the Sustainment domain of EPIS to evaluate the effect of CM strategy vs. self-directed condition on sustainability of the CF-CS use in 640 households across the randomly assigned 32 peri-urban communities in Nigeria. The Lagos State University College of Medicine (LASUCOM) working with the MOH will oversee research coordination in Nigeria.
Read the detailed description
This study will use CM to engage in the community dialogues, organize outreach facilitation, and advocacy for the adoption of bioethanol-based and liquified petroleum gas (LPG) CF-CS across participating households. The choice of CM strategy is deliberate because, unlike western culture, African cultures are largely based on communal hierarchy.
- Conditions
- Hypertension
- Being tested
- Community Mobilization
- Keywords
- Hypertension, Cardiovascular diseases, Clean cookstove, Clean fuel, Community mobilization, Household air pollution
- Medical subject headings
- Hypertension, Cardiovascular Diseases
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Community MobilizationBehavioural
The Community Mobilization (CM) strategy will include: (1) Community advisory board [comprising local community-based organizations, government officials, and residents], that will provide leadership support and buy-in for adoption of Clean Fuel- Clean- Stove (CF-CS) use; (2) Trained MoH community health extension workers, community health officers, community mobilizers and health education officers, who will form community action teams (CAT) to facilitate the implementation of CF-CS use via provision of support, knowledge exchange and performance feedback to the primary cooks in participating households; (3) Community dialogues with residents and households focused on shared concerns on the significance and importance of CF-CS use.
| Study group | Role | What they receive |
|---|---|---|
| CM Intervention Group | Experimental | Cluster. RCT of 16 urban and rural communities. Community mobilizers and health education officers will facilitate use of CF-CS (bioethanol and LPG fuels/stoves) and educate households on HAP exposure throughout the intervention period Receives: Behavioral: Community Mobilization |
| Self-Directed Group | No intervention | Receive information on CFCS use and education on HAP in 16 urban and rural communities; will not receive the CM intervention |
What is being measured
The primary outcome is the main question the study is designed to answer.
Percent of Households Who Have Adopted CF-CS at Baseline
Adoption defined as utilization of the CF-CS for more than 50% of cooking activities based on the metric developed by the Global Alliance for Clean Cookstoves. All traditional stoves and the bioethanol-based CF-CS in the participating households will be equipped with the iButtons SUMs to assess their use. Trained study staff will collect iButton temperature data during household visits.
Measured: Baseline
Percent of Households That Have Adopted CF-CS at Month 12
Adoption defined as utilization of the CF-CS for more than 50% of cooking activities based on the metric developed by the Global Alliance for Clean Cookstoves. All traditional stoves and the bioethanol-based CF-CS in the participating households will be equipped with the iButtons SUMs to assess their use. Trained study staff will collect iButton temperature data during household visits.
Measured: Month 12
Secondary outcomes (2)
Change in Mean Systolic Blood Pressure From Baseline to Month 12
Blood pressure readings assessed with a validated automated BP device. At each visit, three readings will be taken by trained research coordinators using an automated BP monitor. The average of three BP readings will be used as the measure for each study visit.
Measured: Baseline, Month 12
Percent of Participants Who Have Adopted CF-CS at Month 24
Measure of sustainability. Adoption defined as utilization of the CF-CS for more than 50% of cooking activities based on the metric developed by the Global Alliance for Clean Cookstoves. All traditional stoves and the bioethanol-based CF-CS in the participating households will be equipped with the iButtons SUMs to assess their use. Trained study staff will collect iButton temperature data during household visits.
Measured: Month 24
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Sep 2021
- Study start11 Apr 2023
- Primary completion26 Mar 2025
- Study completionJun 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Posted resultsParticipant flow, outcome measures and adverse events reported by the sponsor.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for HypertensionStudies of the same condition, open and under way.
- More trials run by NYU Langone HealthThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 1,280 participants (actual)
Sponsor and investigators
- Lead sponsor
- NYU Langone Health
- Sponsor type
- University, hospital or other
- Collaborators
- National Heart, Lung, and Blood Institute (NHLBI)
- Responsible party
- Sponsor
- Investigators
- Olugbenga Ogedegbe, MD, Principal investigator, NYU Langone HealthChristopher O Olopade, Principal investigator, University of Chicago
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05048147
- Sponsor's protocol ID
- 21-00586
- Other IDs
- R01HL157091
- Status last verified
- Jun 2026
- First submitted
- 1 Sep 2021
- Last updated
- 30 Jun 2026
- Results posted
- Yes, on ClinicalTrials.gov
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: Individual participant data that underlie the results reported in this article, after deidentification (text, tables, figures, and appendices).
Publications
Onakomaiya DO, Mishra S, Colvin C, Ogunyemi R, Aderibigbe AA, Fagbemi T, Adeniji MR, Li S, Kanneh N, Aifah A, Vedanthan R, Olopade CO, Wright K, Ogedegbe G, Wall SP. Stakeholders' perspectives on implementation of a clean fuel: clean stove intervention for reduction of household air pollution and hypertension in Lagos, Nigeria - a qualitative study. BMJ Open. 2026 Jan 9;16(1):e101218. doi: 10.1136/bmjopen-2025-101218.
PubMed 41513415Wright O, Olopade CO, Aifah AA, Fagbemi T, Hade EM, Mishra S, Onakomaiya DO, Kanneh N, Chen W, Colvin CL, Ogunyemi R, Sogbossi E, Erinosho E, Ojengbede O, Taiwo O, Johnson MA, Vedanthan R, Wall S, Lwelunmor J, Idris O, Ogedegbe G. Community mobilisation for adoption of clean cookstoves and clean fuel to reduce household air pollution and blood pressure in Lagos, Nigeria: protocol for a cluster-randomised trial. BMJ Open. 2025 Sep 10;15(9):e098483. doi: 10.1136/bmjopen-2024-098483.
PubMed 40935430
Study at a glance
From the registry record, last updated by the sponsor on 30 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Community Mobilization for Improved Clean Cookstove Uptake, Household Air Pollution Reduction, and Hypertension Prevention
- ClinicalTrials.gov ID
- NCT05048147
- Acronym / sponsor ID
- 21-00586
- Conditions
- Hypertension
- Keywords
- Hypertension, Cardiovascular diseases, Clean cookstove, Clean fuel, Community mobilization, Household air pollution
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 1,280 participants (actual)
- Lead sponsor
- NYU Langone HealthUniversity, hospital or other
- Collaborators
- National Heart, Lung, and Blood Institute (NHLBI)
- Study start
- 11 Apr 2023 (actual)
- Primary completion
- 26 Mar 2025 (actual)
- Study completion
- Jun 2026 (estimated)
- First posted
- 17 Sep 2021 (actual)
- Results
- Posted 30 Jun 2026
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Using a focused implementation research framework, the EPIS (Exploration, Preparation, Implementation and Sustainment) model in a type-2 hybrid design, the study will be conducted in 3 phases: 1) A pre-implementation phase that will use the Exploration and Preparation domains of EPIS to: a) explore barriers and facilitators of Clean Fuel- Clean- Stove (CF-CS) use, and b) develop a culturally-tailored CM strategy for CF-CS use; 2) An Implementation phase that will use the Implementation domain of EPIS to compare in a cluster RCT of 32 peri-urban communities (640 households), the effect of CM vs. a self-directed condition (i.e. receipt of information on CF-CS use without CM) on adoption of CF-CS use; and systolic BP reduction; 3) A post-implementation phase that will use the Sustainment domain of EPIS to evaluate the effect of CM strategy vs. self-directed condition on sustainability of the CF-CS use in 640 households across the randomly assigned 32 peri-urban communities in Nigeria. The Lagos State University College of Medicine (LASUCOM) working with the MOH will oversee research coordination in Nigeria.
Detailed description
This study will use CM to engage in the community dialogues, organize outreach facilitation, and advocacy for the adoption of bioethanol-based and liquified petroleum gas (LPG) CF-CS across participating households. The choice of CM strategy is deliberate because, unlike western culture, African cultures are largely based on communal hierarchy.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| CM Intervention Group | Experimental | Behavioral: Community MobilizationCluster. RCT of 16 urban and rural communities. Community mobilizers and health education officers will facilitate use of CF-CS (bioethanol and LPG fuels/stoves) and educate households on HAP exposure throughout the intervention period |
| Self-Directed Group | No intervention | –Receive information on CFCS use and education on HAP in 16 urban and rural communities; will not receive the CM intervention |
Who may qualify
- Ages
- 18 to 85 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- Primary adult must be a female cook;
- Must not have a paid housemaid;
- Family size must be a minimum of 2 and no more than 7 members;
- Family must use Kerosene, charcoal, LPG, or firewood as primary cooking fuel;
- The person spoken to at enrollment must be the home key decision maker;
Key exclusion criteria (1 listed)
- Does not meet the inclusion criteria
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Community MobilizationThe Community Mobilization (CM) strategy will include: (1) Community advisory board [comprising local community-based organizations, government officials, and residents], that will provide leadership support and buy-in for adoption of Clean Fuel- Clean- Stove (CF-CS) use; (2) Trained MoH community health extension workers, community health officers, community mobilizers and health education officers, who will form community action teams (CAT) to facilitate the implementation of CF-CS use via provision of support, knowledge exchange and performance feedback to the primary cooks in participating households; (3) Community dialogues with residents and households focused on shared concerns on the significance and importance of CF-CS use. | Behavioural | CM Intervention Group |
Primary outcome
Percent of Households Who Have Adopted CF-CS at Baseline
Time frame: Baseline
Adoption defined as utilization of the CF-CS for more than 50% of cooking activities based on the metric developed by the Global Alliance for Clean Cookstoves. All traditional stoves and the bioethanol-based CF-CS in the participating households will be equipped with the iButtons SUMs to assess their use. Trained study staff will collect iButton temperature data during household visits.
Percent of Households That Have Adopted CF-CS at Month 12
Time frame: Month 12
Adoption defined as utilization of the CF-CS for more than 50% of cooking activities based on the metric developed by the Global Alliance for Clean Cookstoves. All traditional stoves and the bioethanol-based CF-CS in the participating households will be equipped with the iButtons SUMs to assess their use. Trained study staff will collect iButton temperature data during household visits.
2 secondary outcomes
Change in Mean Systolic Blood Pressure From Baseline to Month 12
Time frame: Baseline, Month 12
Percent of Participants Who Have Adopted CF-CS at Month 24
Time frame: Month 24
Results and safety
Loading the posted results from ClinicalTrials.gov…
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 Jun 2026.
- Posted resultsParticipant flow, baseline, all outcome measures and adverse events.
- Derived from this study: PubMed 41513415Onakomaiya DO, Mishra S, Colvin C, Ogunyemi R, Aderibigbe AA, Fagbemi T, Adeniji MR, Li S, Kanneh N, Aifah A, Vedanthan R, Olopade CO, Wright K, Ogedegbe G, Wall SP. Stakeholders' perspectives on implementation of a clean fuel: clean stove intervention for reduction of household air pollution and hypertension in Lagos, Nigeria - a qualitative study. BMJ Open. 2026 Jan 9;16(1):e101218. doi: 10.1136/bmjopen-2025-101218.
- Derived from this study: PubMed 40935430Wright O, Olopade CO, Aifah AA, Fagbemi T, Hade EM, Mishra S, Onakomaiya DO, Kanneh N, Chen W, Colvin CL, Ogunyemi R, Sogbossi E, Erinosho E, Ojengbede O, Taiwo O, Johnson MA, Vedanthan R, Wall S, Lwelunmor J, Idris O, Ogedegbe G. Community mobilisation for adoption of clean cookstoves and clean fuel to reduce household air pollution and blood pressure in Lagos, Nigeria: protocol for a cluster-randomised trial. BMJ Open. 2025 Sep 10;15(9):e098483. doi: 10.1136/bmjopen-2024-098483.
- Individual participant dataSharing planned: Yes. Individual participant data that underlie the results reported in this article, after deidentification (text, tables, figures, and appendices).
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Olugbenga Ogedegbe, MD principal investigator
NYU Langone Health
Christopher O Olopade principal investigator
University of Chicago
4 sites in 2 countries: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Community Mobilization in people with Hypertension, run by NYU Langone Health at 4 sites in 2 countries.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 30 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 4 sites in United States, Nigeria. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Yes. Results are posted in the registry (first posted 30 Jun 2026). A summary is in the For doctors view, and the full results are on ClinicalTrials.gov.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Percent of Households Who Have Adopted CF-CS at Baseline (time frame: Baseline). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT05048147, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Jun 2026.