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Color PerceptionEISNCT04836286

Determining the Impact of Emotive Intelligent Spaces

A study testing Emotive Intelligent Spaces (EIS) in people with Color Perception, run by University of Idaho at 1 site in United States.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

Many children (age 3-6) living in the Mountain West (MW) region face unique challenges that can affect their health and welfare, such as lower socioeconomic status, and limited access to healthcare and education. Read more about this study

Who is it for?
Ages 3 to 6 yearsHealthy volunteers can take part
Conditions the study is for
Color Perception
What is being tested?
Emotive Intelligent Spaces (EIS)
Could I receive a placebo?
No, everyone receives an active treatment
How many people
40 participants
Where
1 siteUnited States
Study dates
1 Apr 2021to 21 Jun 2022
Phase
Interventional
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 3 to 6 years
  • All sexes
  • Healthy volunteers accepted
  • Child

Who may be able to join

  • Typically developing children without color blindness

Who cannot join

  • Children with color blindness

Trial locations and contacts

1 site in 1 country.

United States1 site
  • University of Idaho

    Moscow, Idaho, 83844

Other trials in United States

About this study

Official title: Determining the Impact of Emotive Intelligent Space on Children's Self-Regulation and Cognitive Performance

Many children (age 3-6) living in the Mountain West (MW) region face unique challenges that can affect their health and welfare, such as lower socioeconomic status, and limited access to healthcare and education. The proposed project aims to address those health and education gaps by improving children's self-regulation (i.e., the ability to control emotional and behavioral impulses), a critical cognitive skill that underpins future mental health and academic achievement. The project will test the effectiveness of an innovative intervention mechanism, the Emotive Intelligent Space (EIS).

The EIS consists of two adjacent 3 x 5 sq. ft. wooden wall panels with colored LED lights, creating a 90-degree semi-private space. The adaptable colored lightings are controlled by a machine learning algorithm that is developed based on a co-investigator's prior study. The EIS harnesses the power of artificial intelligence to detect children's emotions from physiological data in real-time and to translate physiological signals into environmental changes (i.e., adaptable colored lighting) that adequately respond to children's emotions, resulting in improved self-regulation, physiological stress responses, and cognitive performance.

The objective of this proposal is to determine the effect of EIS on children's (age 3-6) self-regulation, physiological, and cognitive outcomes by employing a repeated ABAB experimental design (A = no intervention, B = EIS intervention). The hypothesis is that EIS will positively impact children's self-regulation, physiological stress response, and cognitive performance. Based on a priori power analysis, 40 preschool and kindergarten children will be recruited from early childhood programs in the rural areas near Moscow, ID. During the experiment, children will be assessed under a combination of A and B conditions. A digital wristband will capture children's real-time physiological responses (i.e., Galvanic skin response, body temperature, and blood volume pulse). A machine learning algorithm will immediately translate the physiological data into three basic emotions (i.e., happy, angry/fearful, sad) represented by children's choice of colors on the EIS. A series of ANCOVA analyses will be used to determine the mean differences in self-regulation, physiological, and cognitive scores under baseline and treatment conditions.

Read the detailed description

Specific Aims

The percentage of young children living in the Mountain West (MW) rural areas is higher than the national average, placing them at a greater risk of poorer health and education outcomes. The proposed project aims to improve those young children's self-regulation - a critical cognitive skill that underpins future mental health and academic outcomes. Self-regulation has been studied as a promising treatment of various mental disorders such as depression and anxiety. A longitudinal study indicates a strong association between kindergarten children's self-regulation skill and their inhibitory control two decades later (inhibitory control was indicated by substance abuse, crimes, and mental disorders). The lack of inhibitory control is a prominent issue among adults in the MW region, as suggested by a nation-wide longitudinal study, with several MW states' average scores ranked near the bottom in the U.S. 7(e.g., Idaho#37, Wyoming#46, Nevada#50). Research also linked the early self-regulation skill to long-term academic achievement, as shown in several early literacy and mathematics intervention studies, further emphasizing an urgent need for interventions targeting self-regulation during a developmentally sensitive age period (age 3-6). To reduce rural children's health and education disparities, we propose to test the effectiveness of an innovative intervention mechanism, Emotive Intelligent Space (EIS), on children's self-regulation, physiological, and cognitive outcomes.

The EIS consists of two 3 x 5 sq. ft. wooden wall panels with LED lights, creating a 90-degree semi-private space. The adaptable colored lightings are controlled by a machine learning algorithm that is developed based on a co-investigator's published prior research11. The EIS harnesses the power of artificial intelligence to detect children's emotions from physiological data collected by a digital wristband in real-time and to translate these data into environmental changes (i.e., adaptable colored lighting) that adequately respond to children's emotions12,13. The colored lighting on the EIS is a developmentally appropriate intervention mechanism for young children (age 3-6) for their non-invasive, adaptive, responsive, and low-cost design.

The purpose of this proposal is to determine the effect of the EIS on children's behavioral, physiological, and cognitive outcomes using a quasi-experimental design. Forty children in rural areas near Moscow, ID will be recruited via existing collaborative relationships such as U of I research extension programs and Rural Sociology and Economics programs. The EIS could potentially alleviate many challenges facing rural families with young children (e.g., limited access to affordable, quality health and education resources). In the specific aims listed below, children's age, gender, and socioeconomic status (SES) will be included as covariates.

Specific Aim 1: To determine whether EIS influences children's self-regulation. We hypothesize that children will demonstrate better self-regulation under the EIS condition than under the baseline condition.

Specific Aim 2: To determine whether EIS impacts children's physiological responses. We hypothesize that children under the EIS condition will exhibit reduced stress responses (e.g., Improved galvanic skin response, body temperature, and blood volume pulse), as compared to their baseline scores.

Specific Aim 3: To determine whether EIS affects children's cognitive performance. We hypothesize that children under the EIS color treatment will have better cognitive performance scores than their scores under the baseline condition.

Research Strategy

Approach Participants. Based on the priori power analysis (described in a later section), we will recruit 40 typically developing children (3-6 years old) from local early childhood programs in the rural areas near Moscow, ID, where the University of Idaho (U of I) is located. Preliminary testing will be conducted with the children in the Child Development Lab that is affiliated with the PI's home department. All participants will undergo a color deficiency assessment (i.e., Ishihara Color Vision Test) to determine their eligibility.

Setting. The study will take place in the Ramsay Research Suite in the Niccolls Building on the U of I main campus. The EIS will be securely installed in a corner of the research lab that is 20 feet 6 inches wide by 45 feet long with a ceiling height of 9 feet 9 inches. The room has three windows on the east side, and the window blinds are always closed to maintain the optimal temperature. There are four round table and four chairs in the lab's performance area. The lab has white walls, vinyl flooring, and dim fluorescent lightings.

The EIS, our intervention mechanism, consists of two double-layer wooden panels. Each panel is 3 feet wide by 5 feet high and made from double layers of wood that allow colored LED lights to diffuse evenly through the panels. The EIS will be placed on the left and front of participants, creating a 90-degree semi-private space.

Research Method. A reversal within-group design (i.e., ABAB) method will be used. During the first phase, A, a baseline and control will be established for the dependent variables - the level of child behavior under the natural lighting before the intervention is introduced. If the dependent variables (i.e., self-regulation, physiological responses, and cognitive performance) changed with the introduction of the intervention and then returned to the baseline scores with the removal of the intervention, we can conclude that there is strong evidence of a treatment effect. The ABAB design greatly increases the internal validity of this project.

Procedures. Participating parents will contact the research team to schedule an initial meeting (Day 1) where they will complete five tasks: 1) Researchers will explain the research procedure. 2) The participating children's parents will sign informed consent forms and complete a demographic survey. 3) Each child will undergo a color deficiency test to determine their eligibility for the study. Eligible participants are typically developing children without color deficiencies. 4) Eligible participants will select colors to represent three basic emotions (sad, happy, and angry/fearful) among randomly arranged six colored cards (red 5R 7/8, yellow 5Y 9/8, green 5G 7/8, blue 5B 6/8, purple 5P 7/8, and white N 9.5) representing the major color families in the Munsell color system, which was used in a co-investigator's previous study36. Each child's preferred colors will be used in their treatment conditions. 5) Parents will schedule another appointment for the experiment.

On the experiment day (Day 2), a trained research assistant will first obtain the participating child's verbal assent. The research assistant will then lead the child to the research lab, describe the protocol, and ask the child to wear a digital wristband and practice tasks while wearing the wristband. At the beginning of each experiment condition, the child will be asked to describe their current emotional status using a Q-sort (a chart with faces representing different emotions) to triangulate EIS emotion interpretation data. To establish the baseline, children complete tasks (Head-Toes-Knees-Shoulders [HTKS] form A and Woodcock-Johnson-4 [WJ-4] cognitive assessment form A), which will take 5-7 minutes. The HTKS task will be video recorded and used for self-regulation coding. The child will then go to a different room to rest for 5 minutes while the research assistant stages the treatment condition (i.e., program the child preferred colors in the computer). For the next treatment condition, children will return to the lab after a brief rest period and complete a parallel version of the two tasks completed under the baseline condition (i.e., HTKS and WJ-4 form Bs; to mitigate threats to internal validity) with the presence of EIS. Each child will repeat the same procedure with another set of baseline and intervention conditions. The entire data collection session will last 30 to 40 minutes. Light snacks will be available on-site for the children during rest periods. Participants will receive a $40-dollar gift-card and books/toys as incentives.

Measures. The impact of EIS on children's self-regulation and cognitive performance will be assessed using multiple measures. Three outcomes of this study include children's self-regulation, physiological responses, and cognitive performance. Each outcome will be measured under the baseline and treatment conditions. These measurements are discussed under each specific aim as follows.

Aim 1. To determine whether EIS influences children's self-regulation, controlling for gender, age, and socioeconomic status (SES). The outcome of Aim 1 (self-regulation) will be measured by the HTKS task, which assesses a child's self-regulation. This task requires cognitive skills such as inhibitory control, attention, and working memory. Children will be asked to play a game where they must do the opposite of what the experimenter says. It is a well-validated and reliable measure of self-regulation.

Aim 2. To determine whether EIS impacts children's physiological responses, controlling for age, gender, and SES. The outcome of Aim 2 (physiological response) will be measured by E4 Wristbands. Physiological data (i.e., Galvanic skin response, body temperature, blood volume pulse) are gathered in real-time with a medical-grade wearable device (i.e., E4 wristbands).

Aim 3. To determine whether EIS affects children's cognitive performance, controlling for age, gender, and SES. The outcome of Aim 3 (cognitive performance) will be measured by WJ-4 - Number Reversed subset. WJ-4 is a brief, age-appropriate, and well-validated cognitive ability assessment that evaluates young children's ability to retrieve and retain information required for ongoing cognitive processes.

Covariates (i.e., children's age, gender, and SES) will be measured with a demographic questionnaire. SES will be calculated based on household annual income and parents' highest education level. The composite SES score will be calculated as the unweighted sum of the z scores, ranging from -3.02 to 18.

Statistical Analysis. We will compare physiological, self-regulation, and cognitive mean scores under baseline and intervention conditions using repeated-measures ANCOVA. We will test the null hypothesis that there is no difference in the dependent variables between time points 1-2 (A-B), 2-3 (B-A) and 3-4 (A-B) after controlling for the covariates (i.e., children's gender, age, and SES).

Being tested
Emotive Intelligent Spaces (EIS)
Keywords
Self-regulation, Color-emotion association, Cognitive performance
Medical subject headings
Self-Control

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Emotive Intelligent Spaces (EIS)Behavioural

    The EIS leverages innovations across multiple disciplines, including sensory environment, computer science, psychology, and real-time human-computer interface. The colors of the LED lights on the EIS wooden panels are controlled by an artificial intelligence computer algorithm that will translate children's physiological responses (Galvanic skin response, body temperature, and blood volume pulse), captured by a digital wristband, into their emotional state and the associated preferred colored lighting. The algorithm was created in a co-investigator's published study11, using fuzzy logic and machine learning techniques (i.e., Decision Tree; accuracy 86%).To successfully carry out this project, our team blends expertise in educational psychology, early intervention, computer science, architecture, and interior design.

Study groups in NCT04836286
Study groupRoleWhat they receive
single group repeated designExperimentalThe Emotive Intelligent Spaces (EIS) leverages innovations across multiple disciplines, including sensory environment, computer science, psychology, and real-time human-computer interface. The colors of the LED lights on the EIS wooden panels are controlled by an artificial intelligence computer algorithm that will translate children's physiological responses (Galvanic skin response, body temperature, and blood volume pulse), captured by a digital wristband, into their emotional state and the associated preferred colored lighting. The algorithm was created in a co-investigator's published study, using fuzzy logic and machine learning techniques (i.e., Decision Tree; accuracy 86%).To successfully carry out this project, our team blends expertise in educational psychology, early intervention, computer science, architecture, and interior design.
Receives: Behavioral: Emotive Intelligent Spaces (EIS)

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Self-regulation

    Self-regulation will be measured by the Head Toes Knees Shoulder task. This task measures cognitive skills such as inhibitory control, attention, and working memory, which are indicators of self-regulation. Children will be asked to play a game where they must do the opposite of what the experimenter says.

    Measured: 10 minutes

  2. Body temperature

    Body temperature will be measured in fahrenheit using the wristband.

    Measured: 30 minutes

  3. Galvanic skin response

    Skin Conductance (SC) will be measured as an indicator of the continuous variations in the electrical characteristics of the skin, using the wristband.

    Measured: 30 minutes

  4. Blood volume pulse

    Blood volume pulse will be measured as the number of heart beat per minutes, using the wristband.

    Measured: 30 minutes

  5. Cognitive performance

    This outcome will be measured with will be measured as working memory efficiency by the Woodcock Johnson Number Reversed subset. WJ-4 is a brief, age-appropriate, and well-validated cognitive ability assessment that evaluates young children's ability to retrieve and retain information required for ongoing cognitive processes.

    Measured: 3 minutes

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted8 Apr 2021
  2. Study start1 Apr 2021
  3. Primary completion21 Jun 2022
  4. Study completion21 Jun 2022

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Supportive care
Allocation
Not applicable
Intervention model
Single group
Model description
ABAB design
Masking
None (open label)
Enrolment
40 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT04836286
Sponsor's protocol ID
20-048
Acronym
EIS
Status last verified
Nov 2022
First submitted
16 Nov 2020
Last updated
3 Nov 2022
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
Yes: Deidentified data can be shared upon researchers' request.

Questions about this trial

What is this clinical trial studying?

A study testing Emotive Intelligent Spaces (EIS) in people with Color Perception, run by University of Idaho at 1 site in United States.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 3 Nov 2022. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Self-regulation (time frame: 10 minutes). The study lists 5 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Nov 2022.

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