Hematopoietic and Lymphoid Cell NeoplasmNCT04754529
Yoga Intervention for the Improvement of Cancer-Related Stress in Cancer Survivors
A study testing Quality-of-Life Assessment, Survey Administration and Yoga in people with Hematopoietic and Lymphoid Cell Neoplasm and Malignant Solid Neoplasm, run by Roswell Park Cancer Institute at 1 site in United States.
Trial summary
This clinical trial develops and test a yoga intervention in improving cancer-related stress in cancer survivors. The online hatha yoga intervention of breathing and movement incorporates both restorative poses, breathing techniques, guided meditation and may reduce stress levels and improve overall quality of health… Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
- What is being tested?
- Quality-of-Life Assessment, Survey Administration and Yoga
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 27 participants
- Where
- 1 siteUnited States
- Study dates
- 11 Nov 2021to 18 Jun 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Age >= 18 years of age
- Have been diagnosed with a cancer and have finished treatment
- Have been cleared for physical activity by a physician or nurse practitioner (physician or nurse practitioner name and date clearance received)
- Participant must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedure
Who cannot join
- Unwilling or unable to complete the assessment in English
- Are pregnant or nursing
- Are unwilling or unable to follow protocol requirements
- Have skeletal instabilities and/or cardio-pulmonary comorbidities
- Have any condition which in the investigator's opinion deems the subject an unsuitable candidate to participate in this study
Trial locations and contacts
1 site in 1 country.
United States1 site
Roswell Park Cancer Institute
Buffalo, New York, 14263
About this study
Official title: Influence of Yoga on Cancer-Related Stress in Cancer Survivors
This clinical trial develops and test a yoga intervention in improving cancer-related stress in cancer survivors. The online hatha yoga intervention of breathing and movement incorporates both restorative poses, breathing techniques, guided meditation and may reduce stress levels and improve overall quality of health in cancer survivors.
Read the detailed description
PRIMARY OBJECTIVE:
- To develop and test the feasibility of a standardized 12-week online hatha yoga intervention (n=30) of breathing and movement incorporating both restorative poses, breathing techniques, guided meditation.
SECONDARY OBJECTIVES:
- To evaluate the yoga intervention in relation to self-reported levels of stress and quality of life in cancer survivors (n=30).
II. Feasibility of collecting blood and saliva at baseline and post-intervention for stress biomarkers, including cortisol and norepinephrine.
EXPLORATORY OBJECTIVE:
- To determine how behavior change, quality of life (QoL), and biomarkers of adrenergic stress, inflammation, and immunosuppression are affected by a 12-week online yoga program completed by cancer survivors.
OUTLINE:
Patients receive online yoga intervention once a week (QW) for 12 weeks.
After completion of study, patients are followed up at 3 months.
- Being tested
- Quality-of-Life Assessment, Survey Administration, Yoga
- Medical subject headings
- Hematologic Neoplasms
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Quality-of-Life AssessmentOther
Also called Quality of Life Assessment
Ancillary studies
Survey AdministrationOther
Ancillary studies
YogaOther
Also called Yoga Therapy
Receive yoga intervention
| Study group | Role | What they receive |
|---|---|---|
| Supportive care (yoga) | Experimental | Patients receive online yoga intervention QW for 12 weeks. Receives: Other: Quality-of-Life Assessment; Other: Survey Administration; Other: Yoga |
What is being measured
The primary outcome is the main question the study is designed to answer.
Proportion of subjects who participate or show high adherence to the intervention
Will be presented as observed proportion and 95% Clopper-Pearson confidence intervals (CIs).
Measured: Up to 12 weeks
Secondary outcomes (3)
Efficacy of the intervention in stress-reduction
Serum cortisol and norepinephrine levels will be measured by blood collection
Measured: Up to 3 months post-intervention
Efficacy of the intervention in stress-reduction
Self report stress
Measured: Up to 3 months post intervention
Efficacy of the intervention in stress reduction
salivary cortisol will be measured by saliva collection
Measured: Up to 3 months post intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted15 Feb 2021
- Study start11 Nov 2021
- Primary completion22 Mar 2024
- Study completion18 Jun 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Hematopoietic and Lymphoid Cell NeoplasmStudies of the same condition, open and under way.
- More trials run by Roswell Park Cancer InstituteThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 27 participants (actual)
Sponsor and investigators
- Lead sponsor
- Roswell Park Cancer Institute
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Kathryn Glaser, Principal investigator, Roswell Park Cancer Institute
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04754529
- Sponsor's protocol ID
- I 891720
- Other IDs
- NCI-2021-00698, I 891720
- Status last verified
- Jun 2025
- First submitted
- 8 Feb 2021
- Last updated
- 22 Jun 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 22 Jun 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Influence of Yoga on Cancer-Related Stress in Cancer Survivors
- ClinicalTrials.gov ID
- NCT04754529
- Acronym / sponsor ID
- I 891720
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 27 participants (actual)
- Lead sponsor
- Roswell Park Cancer InstituteUniversity, hospital or other
- Study start
- 11 Nov 2021 (actual)
- Primary completion
- 22 Mar 2024 (actual)
- Study completion
- 18 Jun 2024 (actual)
- First posted
- 15 Feb 2021 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This clinical trial develops and test a yoga intervention in improving cancer-related stress in cancer survivors. The online hatha yoga intervention of breathing and movement incorporates both restorative poses, breathing techniques, guided meditation and may reduce stress levels and improve overall quality of health in cancer survivors.
Detailed description
PRIMARY OBJECTIVE:
- To develop and test the feasibility of a standardized 12-week online hatha yoga intervention (n=30) of breathing and movement incorporating both restorative poses, breathing techniques, guided meditation.
SECONDARY OBJECTIVES:
- To evaluate the yoga intervention in relation to self-reported levels of stress and quality of life in cancer survivors (n=30).
II. Feasibility of collecting blood and saliva at baseline and post-intervention for stress biomarkers, including cortisol and norepinephrine.
EXPLORATORY OBJECTIVE:
- To determine how behavior change, quality of life (QoL), and biomarkers of adrenergic stress, inflammation, and immunosuppression are affected by a 12-week online yoga program completed by cancer survivors.
OUTLINE:
Patients receive online yoga intervention once a week (QW) for 12 weeks.
After completion of study, patients are followed up at 3 months.
Study design
- Primary purpose
- Supportive care
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Supportive care (yoga) | Experimental | Other: Quality-of-Life Assessment, Other: Survey Administration, Other: YogaPatients receive online yoga intervention QW for 12 weeks. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Age >= 18 years of age
- Have been diagnosed with a cancer and have finished treatment
- Have been cleared for physical activity by a physician or nurse practitioner (physician or nurse practitioner name and date clearance received)
- Participant must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedure
Key exclusion criteria (5 listed)
- Unwilling or unable to complete the assessment in English
- Are pregnant or nursing
- Are unwilling or unable to follow protocol requirements
- Have skeletal instabilities and/or cardio-pulmonary comorbidities
- Have any condition which in the investigator's opinion deems the subject an unsuitable candidate to participate in this study
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Quality-of-Life AssessmentAlso: Quality of Life AssessmentAncillary studies | Other | Supportive care (yoga) |
| Survey AdministrationAncillary studies | Other | Supportive care (yoga) |
| YogaAlso: Yoga TherapyReceive yoga intervention | Other | Supportive care (yoga) |
Primary outcome
Proportion of subjects who participate or show high adherence to the intervention
Time frame: Up to 12 weeks
Will be presented as observed proportion and 95% Clopper-Pearson confidence intervals (CIs).
3 secondary outcomes
Efficacy of the intervention in stress-reduction
Time frame: Up to 3 months post-intervention
Efficacy of the intervention in stress-reduction
Time frame: Up to 3 months post intervention
Efficacy of the intervention in stress reduction
Time frame: Up to 3 months post intervention
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 Jun 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Kathryn Glaser principal investigator
Roswell Park Cancer Institute
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Quality-of-Life Assessment, Survey Administration and Yoga in people with Hematopoietic and Lymphoid Cell Neoplasm and Malignant Solid Neoplasm, run by Roswell Park Cancer Institute at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 22 Jun 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Proportion of subjects who participate or show high adherence to the intervention (time frame: Up to 12 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Jun 2025.