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Management and Epidemiology of Patients Admitted in ICUBLITZ-COVID19NCT04744415

Hospitalizations During Pandemia in the Italian Coronary Care Unit Network

An observational study of Management and Epidemiology of Patients Admitted in ICU, run by Heart Care Foundation at 109 sites in Italy.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

Multicentre, national, observational, retrospective and prospective study. The BLITZ-COVID19 study aims at describing the epidemiology of admissions to Italian Cardiology Intensive Care Units in the COVID-19 infection pandemia, the main aspects of the clinical management of inpatients, their short-term outcome, the… Read more about this study

Who is it for?
Ages 18 years and older
What is being tested?
Epidemiology of admissions
How many people
6,054 participants
Where
109 sitesItaly
Study dates
9 Nov 2020to 23 Mar 2021
How long will I take part?
1 Day
Phase
Observational
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 years and older
  • All sexes
  • No healthy volunteers
  • Adult, Older adult

Study population: All patients aged ≥18 years admitted with any diagnoses to ICU in the specified periods of 30 days each. Retrospecitve phase:(March 1-30, 2020 in the Northern or Centre-North regions; March 15-April 13, 2020 in the Southern or Ventre_South Regions and island. Perspective phase (depending by the IRB approval) in the following periods: November 9-December 8, 2020; November 23-December 22, 2020; January 11-February 9, 2021. (Retrospective study) or in the

Who may be able to join

  • All patients aged ≥18 years admitted with any diagnosis to one of the participating ICU

Who cannot join

  • Refuse to signe consent

Trial locations and contacts

109 sites in 1 country.

109 sites in 1 country

Italy109 sites

  • Ospedale Miulli - U.O.C. Cardiologia - Utic

    Acquaviva delle Fonti, BA

  • Istituto Scientifico Inrca - Uo Cardiologia/Utic/Telecardiologia

    Ancona, AN

  • Ospedale Generale Regionale-Po U. Parini - U.O. Cardiologia E Cure Intensive Card.

    Aosta, AO

  • Po Sant'Ottone Frangipane - U.O.C. Cardiologia - Utic

    Ariano Irpino, AV

  • Ospedale Civile - U.O.C. Cardiologia

    Arzignano, VI

  • Ospedale E. Muscatello - U.O. Di Cardiologia - Utic

    Augusta, SR

  • Aorn San Giuseppe Moscati - U.O. Cardiologia/Utic 'D. Rotiroti'

    Avellino, AV

  • Presidio Ospedaliero Moscati - U.O.C. Cardiologia-Utic

    Aversa, CE

  • Ospedale G. Di Maria - Cardiologia Utic

    Avola, SR

  • Ospedale Santa Maria Annunziata - Cardiologia

    Bagno a Ripoli, FI

  • Aou Policlinico - Uoc Cardiologia Ospedaliera

    Bari, BA

  • Ospedale Di Venere - U.O.C. Di Cardiologia

    Bari, BA

  • Ospedale San Paolo - Cardiologia-Utic

    Bari, BA

  • Presidio Osped. S. Maria Della Speranza - U.O. Di Cardiologia

    Battipaglia, SA

  • Ospedale Di Bentivoglio - U.O. Di Cardiologia

    Bentivoglio, BO

  • Ospedale Maggiore - U.O. Di Cardiologia

    Bologna, BO

  • Ospedale Generale Regionale - Divisione Di Cardiologia

    Bolzano, BZ

  • Ospedale Ss. Trinita' - S.C. Di Cardiologia

    Borgomanero

  • Asst Spedali Civili - Cardiologia

    Brescia, BS

  • Arnas G. Brotzu - Cardiologia Con Utic

    Cagliari, CA

  • Ospedale A. Cardarelli - U.O. Cardiologia E Utic

    Campobasso, CB

  • Ospedale Santo Spirito - Sc Cardiologia

    Casale Monferrato, AL

  • Az. Ospedaliera S. Anna E S. Sebastiano - U.O. Cardiologia-Utic

    Caserta, CE

  • Ospedale San Leonardo - U.O. Di Cardiologia-Utic

    Castellammare di Stabia

  • P.O. Garibaldi Centro - U.O.C. Cardiologia

    Catania, CT

  • Fondazione G. Giglio - U.O. Cardiologia E Utic

    Cefalù, PA

  • Presidio Ospedaliero Citta' Di Castello - U.O. Di Cardiologia

    Città di Castello, PG

  • Ospedale Civile San Paolo - U.O. Cardiologia - Utic

    Civitavecchia, RM

  • Ospedale Santa Maria Dei Battuti - U.O. Di Cardiologia

    Conegliano, TV

  • Ospedale San Giuseppe - Cardiologia

    Empoli, FI

  • Po S. Antonio Abate Di Trapani - U.O.C. Di Cardiologia E Utic

    Erice, TP

  • Ospedale Per Gli Infermi - U.O. Cardiologia - Utic

    Faenza, RA

  • Arcispedale Sant'Anna - U.O. Cardiologia - Utic

    Ferrara, FE

  • Aou Careggi - Cardiologia Interventistica

    Florence, FI

  • Ospedale San Giovanni Di Dio - Cardiologia

    Florence, FI

  • Ospedale Santa Maria Nuova - Hdu Cardiologica/Utic

    Florence, FI

  • Ospedali Riuniti - S.C. Di Cardiologia Univ.-Utic

    Foggia, FG

  • Ospedale San Giovanni Di Dio - Uo Cardiologia - Utic

    Frattamaggiore

  • Ospedale Civile Sacro Cuore Di Gesu' - Uo Cardiologia Utic

    Gallipoli, LE

  • E.O. Ospedali Galliera - S. C. Cardiologia

    Genova, GE

  • Ospedale Generale Di Zona - U.O. Cardiologia - Utic

    Giugliano in Campania

  • Ospedale Moriggia Pelascini - Unita' Operativa Di Cardiologia

    Gravedona, CO

  • Ospedale Gubbio-Gualdo Tadino - U.O. Di Utic E Cardiologia

    Gubbio, PG

  • Ospedale S. Andrea - S.C. Cardiologia

    La Spezia, SP

  • Ospedale Anna Rizzoli - Cardiologia-Utic

    Lacco Ameno

  • Ospedale Generale Di Zona - U.O. Cardiologia - Utic

    Lagonegro, PZ

  • Ospedale S. Maria Goretti - Uoc Malattie Cardiovascolari

    Latina, RM

  • P.O. Lentini - U.O. Di Cardiologia Con Utic

    Lentini, SR

  • Nuovo Ospedale Versilia - Sc Cardiologia

    Lido di Camaiore, LU

  • Ospedali Riuniti - U.O.C. Cardiologia E Utic

    Livorno, LI

  • Aor Papardo - U.O. Cardiologia Con Utic

    Messina, ME

  • Ospedale Piemonte - Cardiologia E Utic

    Messina, ME

  • Centro Cardiologico Monzino - Terapia Intensiva Cardiologica (Utic)

    Milan, MI

  • Ospedale Civile - U.O. Cardiologia

    Mirano, VE

  • Ospedale Civile Di Baggiovara - U.O. Di Cardiologia

    Modena, MO

  • Ospedale Regina Montis Regalis - U.O. Cardiologia-Utic

    Mondovì, CN

  • A.O.U. Cagliari Policlinico Monserrato - Sc Cardiologia Utic Emodinamica

    Monserrato, CA

  • Ospedale San Gerardo - U.O. Cardiologia-Utic

    Monza, MB

  • Aorn Cardarelli - U.O. Cardiologia Con Utic

    Naples

  • Clinica Mediterranea - U.O. Di Cardiologia

    Naples

  • Ospedale Del Mare - U.O. Cardiologia Con Utic

    Naples

  • P.O. Nocera-Pagani - Osp. Umberto I - Uoc Cardiologia - Utic

    Nocera Inferiore, SA

  • Pres. Ospedaliero S. Maria Della Pieta' - U.O. Cardiologia E Utic

    Nola

  • Aou Maggiore Della Carita' - Cardiologia Ii

    Novara, NOVARA

  • Ospedale San Francesco - Cardiologia - Utic

    Nuoro, NU

  • Aor Villa Sofia-Cervello P.O. Cervello - U.O. Cardiologia - Cervello

    Palermo, PA

  • Aor Villa Sofia-Cervello Po Villa Sofia - U.O.C. Cardiologia E Utic - Villa Sofia

    Palermo, PA

  • Centro Cuore Morgagni - U.F. Utic Ed Emodinamica

    Pedara, CT

  • Ospedale Civile Dello Spirito Santo - Utic E Cardiologia Interventistica

    Pescara, PE

  • Casa Di Cura Dr. Pederzoli - Servizio Di Cardiologia

    Peschiera del Garda, VR

  • Ospedale Ss. Cosma E Damiano - U. O. Cardiologia - Utic

    Pescia, PT

  • Ospedale Civile 'Guglielmo Da Saliceto' - Uo Cardiologia

    Piacenza, PC

  • Ospedale Dell'Alta Val D'Elsa - Uosd Cardiologia-Utic

    Poggibonsi, SI

  • Presidio Ospedaliero Luigi Curto - Uo Cardiologia-Utic

    Polla, SA

  • Ospedale Generale Provinciale Lotti - U.O. Malattie Cardiovascolari Vde E Avc

    Pontedera, PI

  • Ospedale Di Pordenone - S.O.C. Cardiologia

    Pordenone, PN

  • Azienda Ospedaliera San Carlo - Ssd Utic

    Potenza, PZ

  • Ospedale Santo Stefano - U.O. Cardiologia

    Prato, PO

  • Ospedale Civile Santa Maria Delle Croci - U.O. Di Cardiologia

    Ravenna, RA

  • P.O. San Camillo de Lellis - U.O.C. Cardiologia

    Rieti, RI

  • Aurelia Hospital - U.O.C Cardiologia

    Roma, RM

  • Clinica Citta' Di Roma - Cardiologia-Utic

    Roma, RM

  • European Hospital - U.O. Cardiologia Interventistica

    Roma, RM

  • Ospedale Fatebenefratelli - U.O.C. Cardiologia

    Roma, RM

  • Ospedale San Camillo - Uoc Cardiologia

    Roma, RM

  • Ospedale Sandro Pertini - Uoc Cardiologia

    Roma, RM

  • Ospedale Sant'Andrea Di Roma - U.O.C. Cardiologia

    Roma, RM

  • PO San Filippo neri - ASL Roma1

    Roma, Roma, 00135

  • Ospedale Santa Maria Del Carmine - Cardiologia

    Rovereto, TN

  • Ospedale Santa Maria Della Misericordia - U.O.C. Cardiologia

    Rovigo, RO

  • Aou S. Giovanni Di Dio-Ruggi D'Aragona - U.O.C. Utic

    Salerno, SA

  • Ospedale S. Anna - U.O.C. Di Cardiologia

    San Fermo della Battaglia, CO

  • Ospedale Nostra Signora Di Bonaria - U.O.C. Cardiologia E Utic

    San Gavino Monreale, SU

  • Ospedale Casa Sollievo Della Sofferenza - Cardiologia - Utic - Riabil Cardiologica

    San Giovanni Rotondo, FG

  • Presidio Ospedaliero - U.O. Cardiologia

    Sanremo, IM

  • Ospedale San Giuseppe E Melorio - U.O.C. Cardiologia Utic

    Santa Maria Capua Vetere, CE

  • Presidio Ospedaliero Di Saronno - U.O.C. Di Cardiologia

    Saronno, VA

  • Ospedale Maggiore Ss. Annunziata - Sc Cardiologia

    Savigliano, CN

  • Ospedale Ignazio Veris Delli Ponti - Uoc Cardiologia-Utic

    Scorrano, LE

  • Presidio Ospedaliero San Rocco - U.O.C. Cardiologia - Utic

    Sessa Aurunca, CE

  • Irccs Policlinico Multimedica - Uo Di Cardiologia

    Sesto San Giovanni, MI

  • Aou Senese Ospedale S. Maria Alle Scotte - U.O.C. Cardiologia Clinico-Chirurg. Utic

    Siena, SI

  • Ospedale Civile - U.O. Cardiologia

    Sondrio, SO

  • Ospedale Santa Chiara - Divisione Di Cardiologia

    Trento, TN

  • Azienda Osp. Cardinale G. Panico - U.O. Cardiologia - Utic

    Tricase, LE

  • Pou Santa Maria Della Misericordia - S.O.C. Cardiologia

    Udine, UD

  • Ospedale San Luca - U.O. Utic - Cardiologia

    Vallo della Lucania, SA

  • Ospedale San Pio Da Pietrelcina - Cardiologia

    Vasto, CH

  • Ospedale Civile San Bortolo - U.O.C. Cardiologia

    Vicenza, VI

Other trials in Italy

About this study

Official title: Epidemiology of the Hospitalizations in the Italian Coronary Care Unit Network at the Time of Covid19

Multicentre, national, observational, retrospective and prospective study.

The BLITZ-COVID19 study aims at describing the epidemiology of admissions to Italian Cardiology Intensive Care Units in the COVID-19 infection pandemia, the main aspects of the clinical management of inpatients, their short-term outcome, the absorption of resources related to their admission.

Read the detailed description

The BLITZ-COVID19 study, aims at describing the epidemiology of admissions to Italian Cardiology Intensive Care Units .

The study is observational, multicentre, national and involves the collection of clinical data, both retrospectively and prospectively, using a web-based system. In conducting the study, no drugs are tested, nor are diagnostic tests or non-pharmacological therapies performed other than those that each participating cardiologist decides to perform following the rules of normal clinical practice. Diagnostic procedures and pharmacological and non-pharmacological therapies habitually prescribed for cardiovascular pathologies, which are the object of hospitalization, and those used in the event of a COVID-19 infection, will be recorded in the database.

Being tested
Epidemiology of admissions

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Epidemiology of admissionsOther

    Cardiology Intensive Care Unit admission

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Impact that COVID-19 infection may have had on the in-hospital mortality

    Impact that COVID-19 infection may have had on the in-hospital mortality of the various clinical conditions admitted to ICU

    Measured: Enrollment

  2. Epidemiology and management of patients admitted to ICU

    The different diagnoses of discharge from the ICU and their frequency will be described. All hospitalized cardiac and non-cardiac pathologies will be listed, with particular reference to any COVID-19 infection.

    Measured: Enrollment

  3. Management of patients admitted to ICU

    Description of the main therapeutic decision in patients hospitalized for the most relevant pathologies

    Measured: Enrollment

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted9 Feb 2021
  2. Study start9 Nov 2020
  3. Primary completion9 Feb 2021
  4. Study completion23 Mar 2021

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Observational model
Cohort
Time perspective
Other
Enrolment
6,054 participants (actual)
Target duration
1 Day
IDs, dates and publications
ClinicalTrials.gov ID
NCT04744415
Sponsor's protocol ID
K22
Acronym
BLITZ-COVID19
Status last verified
Dec 2025
First submitted
2 Feb 2021
Last updated
2 Jan 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
Undecided: Still to be decided

Publications

  • Gulizia MM, Fabbri G, Lucci D, Di Pasquale G, Gabrielli D, Campodonico J, Mauro A, Inciardi R, Di Lorenzo E, Oliva F, Nardi F, Colivicchi F, De Luca L; BLITZ-COVID19 Investigators. Type of hospitalisations and in-hospital outcomes in the Italian coronary care unit network at the time of COVID-19 pandemic: the BLITZ-COVID19 Registry. BMJ Open. 2022 Nov 29;12(11):e062382. doi: 10.1136/bmjopen-2022-062382.

    PubMed 36446450

Questions about this trial

What is this clinical trial studying?

An observational study of Management and Epidemiology of Patients Admitted in ICU, run by Heart Care Foundation at 109 sites in Italy.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 2 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 109 sites in Italy. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Impact that COVID-19 infection may have had on the in-hospital mortality (time frame: Enrollment). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT04744415, which also lists 1 linked publication.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Jan 2026.

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