Clinical Characteristics and Prognostic Factors of Patients With COVID-19 (Coronavirus Disease 2019)

Gender (% of male patients; % of female patients)

Age (in years) at diagnosis

Percentage of patients in each age range (<2; 2-4; 5-14; 15-29; 30-39; 40-49; 50-59; 60-69; 70-79; >= 80).

Percentage of patients with available PCR results (Positive; Negative; Unknown) Percentage of patients with available IgG (immunoglobulin G)/IgM (immunoglobulin M) results (Positive; Negative; Unknown) Percentage of patients using Alcohol/Tobacco/Other substances (Yes/No/Former user/Unknown

Time (in days) since first symptom until diagnosis

Physical examination

• BMI

Physical examination

• Percentage of patients who are pregnant

Physical examination

• Temperature (in degrees Celsius) - Percentage of patients within temperature ranges (in degrees Celsius) (<37, 37-38, >38)

Physical examination

• Heart rate (bmp) - Percentage of patients within low/normal/high ranges of heart rate

Physical examination. Laboratory values at diagnosis

Hematology:

Hemoglobin (g/dl)

Physical examination. Laboratory values at diagnosis

Hematology:

Hemoglobin n(%)

Physical examination. Laboratory values at diagnosis

Hematology:

Red Blood Cells (106/µl)

Physical examination. Laboratory values at diagnosis

Hematology:

Red Blood Cells n(%)

Physical examination. Laboratory values at diagnosis

Hematology:

Platelet count (103/mm3) Leukocyte count (103/mm3) Neutrophils (103/mm3) Lymphocytes (103/mm3) Monocytes (103/mm3) Eosinophils (103/mm3) Basophils (103/mm3)

Physical examination. Laboratory values at diagnosis

Hematology:

Platelet count n(%) Leukocyte count n(%) Neutrophils n(%) Lymphocytes n(%) Monocytes n(%) Eosinophils n(%) Basophils n(%)

Physical examination. Laboratory values at diagnosis

Hematology:

INR n(%)

Physical examination. Laboratory values at diagnosis

Hematology:

INR

Physical examination. Laboratory values at diagnosis

Biochemistry:

Glucose (mg/dl) Total cholesterol (mg/dl) Triglycerides (mg/dl)

Physical examination. Laboratory values at diagnosis

Biochemistry:

Glucose n(%) Total cholesterol n(%) Triglycerides n(%)

Physical examination. Laboratory values at diagnosis

Biochemistry:

Total bilirubin (g/dL)

Physical examination. Laboratory values at diagnosis

Biochemistry:

Total bilirubin n(%)

Physical examination. Laboratory values at diagnosis

Other values:

Creatinine in urine (mg/dl) Glucose in urine (mg/dl)

Physical examination. Laboratory values at diagnosis

Other values:

Creatinine in urine n(%) Glucose in urine n(%)

Physical examination. Laboratory values at diagnosis

Other values:

Procalcitonin level will be reported" (PCT) ng/mL

Physical examination. Laboratory values at diagnosis

Other tests:

pH pH n(%) O2 saturation (%) O2 saturation n(%) FIO2 (%) FIO2 n(%) PAFI (%) PAFI n(%)

Physical examination. Laboratory values at diagnosis

Other tests:

pH

Physical examination. Laboratory values at diagnosis

Other tests:

PH n(%)

Physical examination. Laboratory values at diagnosis

Other tests:

O2 saturation (%) FIO2 (%) PAFI (%)

Physical examination. Laboratory values at diagnosis

Other tests:

O2 saturation n(%) FIO2 n(%) PAFI n(%)

Physical examination. Laboratory values at diagnosis

Other tests:

pCO2 (mmHg) pO2 (mmHg)

Physical examination. Laboratory values at diagnosis

Other tests:

pCO2 n(%) pO2 n(%)

• Percentage of patients with family history of selected comorbidities
• Percentage of patients with existing selected comorbidities at diagnosis: Cardiovascular disease, Hypertension, Ischemic stroke, Heart Disease (Cardiopathy), etc.
• Percentage of patients with medication use/procedures prior to diagnosis. The following medications/treatments will be considered: ACEI (angiotensin converting enzyme inhibitors), ARB (angiotensin receptor blocker), Diuretics, Beta-blocker, etc.
• Percentage of patients showing the following signs and symptoms at diagnosis: Cough, Fever, Dyspnoea, Respiratory crackles, Diarrhoea, etc.
• Percentage of patients showing the following signs and symptoms after diagnosis: Thromboembolic Disorder, Venous thrombosis, Pulmonary thromboembolism, Upper gastrointestinal bleeding, etc.

Percentage of patients assigned to the following procedures after diagnosis: Chest x-ray, Ultrasonography of thorax,Ultrasonography of lung, High resolution computed tomography, Computer tomography of chest, Echocardiogram, EKG Percentage of patients assigned to the following treatments after diagnosis: Oxygen therapy (Oxygen administration by nasal cannula, Oxygen administration by Venturi mask, High concentration oxygen therapy), Prone position, Noninvasive ventilation, Invasive mechanical ventilation,Tracheotomy, Extubation of trachea.

Percentage of patients (and mean duration of treatment in days) prescribed with the following pharmacological agents after diagnosis: Lopinavir + Ritonavir, Darunavir + Ritonavir, Darunavir + Cobicistat, IFN (Interferon)- β1b, Chloroquine, Hydroxychloroquine, Antibiotics, Acetylcysteine,Corticosteroids,Selective immunosuppressants, Cyclosporine, Remdesivir, Antithrombotic agents (anticoagulants), Inhibitors of platelet aggregation.

The outcomes of COVID-19 (discharge, hospitalization, transfer to ICU/ mechanical medical ventilation, in-hospital death) in correlation to patients' clinical and demographic characteristics, and treatment received

• Percentage of patients with selected comorbidities (see complete list above) at diagnosis in each outcome group (ICU-no ICU; hospitalization-no hospitalization; discharge-no discharge; death-no death)
• Percentage of patients showing selected sings and symptoms (see complete list above) at diagnosis in each outcome group (ICU-no ICU; hospitalization-no hospitalization; discharge-no discharge; death-no death)