Visual Health of Virtual RealityNCT04530773
Developing and Validating VR-Enabled Ophthalmic Clinics: A New Paradigm for Visual Function Testing
A study testing Watch VR movies/ Play VR games in people with Visual Health of Virtual Reality, run by Zhongshan Ophthalmic Center, Sun Yat-sen University at 1 site in China.
Trial summary
This study aimed to design and validate a VR-based ophthalmic clinic that replicates traditional tests of visual acuity, stereopsis, and contrast sensitivity within an immersive digital environment. Read more about this study
- Who is it for?
- Ages 18 to 60 yearsHealthy volunteers can take part
- Conditions the study is for
- Visual Health of Virtual Reality
- What is being tested?
- Watch VR movies/ Play VR games
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 36 participants
- Where
- 1 siteChina
- Study dates
- 1 Jan 2024to 31 Dec 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 60 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- The study included healthy individuals older than 18 years of age with a best-corrected visual acuity (BCVA) of <0.1 logarithm of minimum angle of resolution (logMAR) and no ongoing or prior history of ocular or systemic disease.
Who cannot join
- The study excluded healthy individuals younger than 18 years of age with a best-corrected visual acuity (BCVA) of >0.1 logarithm of minimum angle of resolution (logMAR) with ongoing or prior history of ocular or systemic disease.
Trial locations and contacts
1 site in 1 country.
About this study
This study aimed to design and validate a VR-based ophthalmic clinic that replicates traditional tests of visual acuity, stereopsis, and contrast sensitivity within an immersive digital environment. Using a rigorously developed system based onprogrammable interfaces, and standardized testing paradigms, we compared VR assessments against gold-standard clinical tools in a cohort of healthy adult participants. Key outcomes included test consistency, correlation, user acceptability, visual fatigue, and time efficiency. Our findings offer evidence for the viability of VR as a platform for remote ophthalmic testing and pave the way for scalable digital eye care delivery.
- Conditions
- Visual Health of Virtual Reality
- Being tested
- Watch VR movies/ Play VR games
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Watch VR movies/ Play VR gamesBehavioural
The healthy individuals will watch VR movies or play VR games with different Physical parameters for 60 minutes.
| Study group | Role | What they receive |
|---|---|---|
| GROUP1 | Experimental | Not described Receives: Behavioral: Watch VR movies/ Play VR games |
| GROUP2 | Experimental | Not described Receives: Behavioral: Watch VR movies/ Play VR games |
| GROUP3 | Experimental | Not described Receives: Behavioral: Watch VR movies/ Play VR games |
| GROUP4 | Experimental | Not described Receives: Behavioral: Watch VR movies/ Play VR games |
| GROUP5 | Experimental | Not described Receives: Behavioral: Watch VR movies/ Play VR games |
What is being measured
The primary outcome is the main question the study is designed to answer.
Accommodative Response
The actual amount of accommodation that exists is measured with a skiascope
Measured: 60 min
AC/A Ratio
The ratio of accommodation convergence to accommodation is measured and calculated by maddox
Measured: 60 min
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted28 Aug 2020
- Study start1 Jan 2024
- Primary completion31 Dec 2024
- Study completion31 Dec 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Visual Health of Virtual RealityStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Factorial
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 36 participants (actual)
Sponsor and investigators
- Lead sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Jin Yuan, Zhongshan Ophthalmic Center, Sun Yat-sen University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04530773
- Sponsor's protocol ID
- 2020KYPJ092
- Status last verified
- Jan 2024
- First submitted
- 24 Aug 2020
- Last updated
- 11 Jun 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 11 Jun 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Developing and Validating VR-Enabled Ophthalmic Clinics: A New Paradigm for Visual Function Testing
- ClinicalTrials.gov ID
- NCT04530773
- Acronym / sponsor ID
- 2020KYPJ092
- Conditions
- Visual Health of Virtual Reality
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 36 participants (actual)
- Lead sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen UniversityUniversity, hospital or other
- Study start
- 1 Jan 2024 (actual)
- Primary completion
- 31 Dec 2024 (actual)
- Study completion
- 31 Dec 2024 (actual)
- First posted
- 28 Aug 2020 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aimed to design and validate a VR-based ophthalmic clinic that replicates traditional tests of visual acuity, stereopsis, and contrast sensitivity within an immersive digital environment. Using a rigorously developed system based onprogrammable interfaces, and standardized testing paradigms, we compared VR assessments against gold-standard clinical tools in a cohort of healthy adult participants. Key outcomes included test consistency, correlation, user acceptability, visual fatigue, and time efficiency. Our findings offer evidence for the viability of VR as a platform for remote ophthalmic testing and pave the way for scalable digital eye care delivery.
Study design
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Factorial
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 5
| Arm | Type | Receives |
|---|---|---|
| GROUP1 | Experimental | Behavioral: Watch VR movies/ Play VR games |
| GROUP2 | Experimental | Behavioral: Watch VR movies/ Play VR games |
| GROUP3 | Experimental | Behavioral: Watch VR movies/ Play VR games |
| GROUP4 | Experimental | Behavioral: Watch VR movies/ Play VR games |
| GROUP5 | Experimental | Behavioral: Watch VR movies/ Play VR games |
Who may qualify
- Ages
- 18 to 60 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (1 listed)
- The study included healthy individuals older than 18 years of age with a best-corrected visual acuity (BCVA) of <0.1 logarithm of minimum angle of resolution (logMAR) and no ongoing or prior history of ocular or systemic disease.
Key exclusion criteria (1 listed)
- The study excluded healthy individuals younger than 18 years of age with a best-corrected visual acuity (BCVA) of >0.1 logarithm of minimum angle of resolution (logMAR) with ongoing or prior history of ocular or systemic disease.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Watch VR movies/ Play VR gamesThe healthy individuals will watch VR movies or play VR games with different Physical parameters for 60 minutes. | Behavioural | GROUP1, GROUP2, GROUP3, GROUP4, GROUP5 |
Primary outcome
Accommodative Response
Time frame: 60 min
The actual amount of accommodation that exists is measured with a skiascope
AC/A Ratio
Time frame: 60 min
The ratio of accommodation convergence to accommodation is measured and calculated by maddox
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 11 Jun 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Watch VR movies/ Play VR games in people with Visual Health of Virtual Reality, run by Zhongshan Ophthalmic Center, Sun Yat-sen University at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 11 Jun 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Accommodative Response (time frame: 60 min). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 11 Jun 2025.