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Access to Emergency SurgeryNCT04487496

Determinants of Access to Emergency Surgery at the University College Hospital, Ibadan

An observational study of Access to Emergency Surgery, run by University College Hospital, Ibadan at 1 site in Nigeria.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

Access to surgery is reported to be significantly lower in low income countries like Nigeria, and upwards of 5 billion people globally lack safe access to surgery. The investigators intend to answer the question, what is the burden of access to acute care surgery alongside their determinants in the University College… Read more about this study

Who is it for?
Any ageHealthy volunteers can take part
Conditions the study is for
Access to Emergency Surgery
How many people
87 participants
Where
1 siteNigeria
Study dates
17 Aug 2020to 30 Sep 2022
Phase
Observational
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages Any age
  • All sexes
  • Healthy volunteers accepted
  • Child, Adult, Older adult

Study population: This shall comprise all the healthcare givers related to the surgical specialties in UCH, these include the following departments: surgery, plastics and reconstructive and aesthetic surgery, neurological surgery, orthopaedics and trauma, otorhinolaryngology, ophthalmology, obstetrics and gynaecology, oral and maxillofacial surgery, anaesthesia as well as the accident and emergency. The case-records of all patients presenting through the emergency room of University College Hospital Ibadan, requiring emergency surgery as determined by the surgical services.

Who may be able to join

  • All recruited doctors who give consent
  • All eligible case records of surgical emergencies determined by the surgical services.

Who cannot join

  • Case records of patients to be directly managed by the principal investigator
  • Case records of patients who die before surgery

Trial locations and contacts

1 site in 1 country.

Nigeria1 site
  • University College Hospital

    Ibadan, Oyo State, 5116

Other trials in Nigeria

About this study

Access to surgery is reported to be significantly lower in low income countries like Nigeria, and upwards of 5 billion people globally lack safe access to surgery. The investigators intend to answer the question, what is the burden of access to acute care surgery alongside their determinants in the University College Hospital, Ibadan (UCH). The expected results from this study will provide basis for evidence-based policy aimed at improving time-to-emergency surgery and thus improve outcomes.

A cross-sectional doctors' survey and a prospective case records review would be the study designs; using a minimum of fifty-one participants and case records respectively. The doctors will be selected randomly from all the surgical services and the emergency department in the UCH, ensuring a fairly equal allocation. The case notes will be of patients in the UCH requiring emergency surgery that had surgeries.

Data from this study will be entered and analysed using STATA/MP 15.0 (Stata Corp, College station, TX).

Read the detailed description

Introduction The Sustainable Development Goals (SDG) mandates that to improve health and health equity, every global citizen has a right to improved essential and emergency surgical care and States are morally obliged to ensure this (Chawla, Rutkov, Garber, Kushner, \& Stewart, 2017). These were ratified by the World Health Assembly Resolution 68.15 that made access to quality and timely Emergency and Essential Surgical Care and Anaesthesia (EESCA) a component of the Universal Health Coverage (Chawla, Rutkov, Garber, Kushner, \& Stewart, 2017). It is accepted that prompt access to surgical care is cardinal for the reduction of the potentially associated morbidity and mortality inherent in surgical conditions (Scott, et al., 2016). Care following trauma has been proposed as a model for accessing indiscriminate care, as care seeking here is mostly guided by injury severity (Scott, et al., 2016); hence, we would use trauma related metrics to present a rationale for this study.

Civilian trauma mortality have been postulated to follow the so-called tri-modal death peaks, 50% of those mortalities -representing the first peak- present emergency care physicians with the dilemma of almost sudden death (occurring within seconds to minutes), thus they very rarely survive past the trauma field (Solomon, Warwick, \& Nayagam, 2010). The other 50% is distributed as 30% and 20% for the second and third peaks respectively. These casualties are actually capable of presenting for care, as the second peak deaths will occur within minutes to hours and is nicknamed 'Golden hour' because a carefully executed trauma algorithm will ensure to avert a mortality in that situation; attention here is placed on carefully identifying potentially catastrophic haemorrhage of the overt or covert forms, the efficient and rapid establishment of haemostasis and treatment of circulatory shock (Solomon, Warwick, \& Nayagam, 2010). The third peak deaths may represent a failure of preventing and treating infections as well as failure to co-manage other morbidities in these patients; there is a resultant two-week interval before such septic processes are significantly established to threaten survival of the post-acute phase trauma patient (World health statistics 2019: monitoring health for the SDGs, sustainable development goals. Licence: CC BY-NC-SA 3.0 IGO., 2019; Solomon, Warwick, \& Nayagam, 2010).

Statement of problem Poisoning, motor vehicle crashes and firearm injuries are the leading causes of Emergency Room (ER) visits in the United States of America (USA); clearly, with the exception of poisoning, trauma-related causes necessitate most visits in the USA, in accordance with reports of trauma being the leading cause of death for persons under 45 years of age in the USA (Gani, Sakran, \& Canner, 2017; Carr, et al., 2017). The annual trauma-related ER visits in the US are about 29 million visits, resulting in 2.8 million hospitalizations and 180 thousand deaths (Carr, et al., 2017) and the American region's Road Traffic Mortality Rate (RTMR) at 15.6 per 100,000 (World health statistics 2019: monitoring health for the SDGs, sustainable development goals. Licence: CC BY-NC-SA 3.0 IGO., 2019). These are despite that 88.3% of the American population have access to high level trauma centres (Carr, et al., 2017), the American region has a Universal Health Coverage (UHC) service coverage index of 78% and Density of Medical Doctors (DMD) of 23.3 per 10,000 population.

It is worthy of note that globally, five billion people lack access to safe and affordable surgery when needed, irrespective of the fact that globally 312 million surgical procedures are done annually, only about 6% of these are done in the poorest countries (Watters, Guest, Tangi, Shrime, \& Meara, 2018). This is against the fact that in 2016 the low and middle income earning countries account for 93% of the 1.3 million people reported to have had road traffic accidents (RTA) and the upwards of 50 million people that were injured (World health statistics 2019: monitoring health for the SDGs, sustainable development goals. Licence: CC BY-NC-SA 3.0 IGO., 2019). Their survival may have been improved if the Healthy people 2020 benchmark on access to trauma care of 60 minutes could be met (Carr, et al., 2017); well this isn't the case as in 2016, RTMR per 100,000 population was 26.6, 27.5 and 19.2 in the African region, low and middle income earning countries unlike 8.3 in the high income earning countries and the UHC service coverage indices were 44%, 78% and 73% respectively for the African, American and European regions respectively and a similar tale for the DMD per 10,000 population at 2.8, 23.3 and 33.8 for the African, American and European regions respectively (World health statistics 2019: monitoring health for the SDGs, sustainable development goals. Licence: CC BY-NC-SA 3.0 IGO., 2019).

Aim of the study The study aims to identify the determinants of access to emergency surgeries in the University College Hospital Ibadan

Objectives of the study

General: To establish the determinants of access to emergency surgeries at the University College Hospital Ibadan

Specific:

To establish the average time-to-surgery for surgical emergencies in the University College Hospital Ibadan To establish the burden of delayed emergency surgeries in University College Hospital Ibadan.

To determine the patient related causes of delayed emergency surgeries in the University College Hospital Ibadan.

To elucidate the healthcare giver related causes of delayed emergency surgeries in the University College Hospital Ibadan.

To examine the institutional factors related to the causes of delayed emergency surgeries in the University College Hospital Ibadan.

To aggregate the determinants of causes of delayed emergency surgeries in the University College Hospital Ibadan and present a multivariate analysis of their inter-relation.

Keywords
Emergency surgery, Access to emergency surgery, Acute surgical care, Acute trauma care

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Time-to-surgery

    This will collect information about the time from specific event (onset of symptoms, entry into the hospital, diagnosis and decision for surgical care) to the actual onset of the emergency surgery

    Measured: One year

  2. Factors affecting onset of emergency surgery

    This will gather from the doctors' survey and the prospective case records review, the patient related, healthcare giver related and institutional related determinants of access to emergency surgery

    Measured: One year

Secondary outcomes (1)
  1. Post-operative outcome

    This will collect outcome data from the case records review, these will include the presence or absence of post-operative complications, the length of hospital stay and final disposition of the patient

    Measured: One year

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted27 Jul 2020
  2. Study start17 Aug 2020
  3. Primary completion30 Jun 2022
  4. Study completion30 Sep 2022

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Observational model
Other
Time perspective
Cross-sectional
Enrolment
87 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT04487496
Sponsor's protocol ID
U1111-1254-0480
Status last verified
May 2023
First submitted
22 Jun 2020
Last updated
12 May 2023
Results posted
No
Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
Yes: The de-identified data set will be developed and presented in a share-able format and most likely deposited in an online data repository

Publications

  • Carr BG, Bowman AJ, Wolff CS, Mullen MT, Holena DN, Branas CC, Wiebe DJ. Disparities in access to trauma care in the United States: A population-based analysis. Injury. 2017 Feb;48(2):332-338. doi: 10.1016/j.injury.2017.01.008. Epub 2017 Jan 3.

    PubMed 28069138
  • Chawla KS, Rutkow L, Garber K, Kushner AL, Stewart BT. Beyond a Moral Obligation: A Legal Framework for Emergency and Essential Surgical Care and Anesthesia. World J Surg. 2017 May;41(5):1208-1217. doi: 10.1007/s00268-016-3866-6.

    PubMed 28180984
  • Gani F, Sakran JV, Canner JK. Emergency Department Visits For Firearm-Related Injuries In The United States, 2006-14. Health Aff (Millwood). 2017 Oct 1;36(10):1729-1738. doi: 10.1377/hlthaff.2017.0625.

    PubMed 28971917
  • MC, R. (1991). An in-vivo of the microbial proliferation beneath transport film dressings in: Maki DG, ed, International congress and symposium series No 179, improving catheter site care. London Series (pp. 29-33). London: Royal Society of Medicine.

  • Scott JW, Havens JM, Wolf LL, Zogg CK, Rose JA, Salim A, Haider AH. Insurance status is associated with complex presentation among emergency general surgery patients. Surgery. 2017 Feb;161(2):320-328. doi: 10.1016/j.surg.2016.08.038. Epub 2016 Oct 4.

    PubMed 27712875
  • Solomon, L., Warwick, D., & Nayagam, S. (2010). Apley's System of Orthopaedics and Fractures. London: Hodder Arnold.

  • Watters DA, Guest GD, Tangi V, Shrime MG, Meara JG. Global Surgery System Strengthening: It Is All About the Right Metrics. Anesth Analg. 2018 Apr;126(4):1329-1339. doi: 10.1213/ANE.0000000000002771.

    PubMed 29547428
  • World health statistics 2019: monitoring health for the SDGs, sustainable development goals. Licence: CC BY-NC-SA 3.0 IGO. (2019). Geneva: World Health Organization. Retrieved August 15, 2019, from https://www.who.int/gho/publications/world_health_statistics/2019/EN_WHS_2019_Main.pdf?ua=1

Questions about this trial

What is this clinical trial studying?

An observational study of Access to Emergency Surgery, run by University College Hospital, Ibadan at 1 site in Nigeria.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 2 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 12 May 2023. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Nigeria. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Time-to-surgery (time frame: One year). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT04487496, which also lists 8 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 12 May 2023.

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