Postural and Suprapostural Performance During Dual Tasking in Patients With Parkinson's DiseaseNCT04288024

The Learning Effects of Task-priority Strategy on Dual-task Weight Shifting and Brain Plasticity in Patients With Parkinson's Disease

A study testing Weight-shifting training in people with Postural and Suprapostural Performance During Dual Tasking in Patients With Parkinson's Disease, run by National Taiwan University Hospital at 1 site in Taiwan.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record

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Trial summary

(1) postural and suprapostural performance of a dual task would be differently affected by the strategy of task prioritization and (2) the cortical activation is different according to attentional focus strategies. Read more about this study

Who is it for?: Ages 50 to 85 years
Conditions the study is for: Postural and Suprapostural Performance During Dual Tasking in Patients With Parkinson's Disease
What is being tested?: Weight-shifting training
Type of treatment: Lifestyle or therapy programme
Could I receive a placebo?: No, everyone receives an active treatment
How many people: 28 participants
Where: 1 siteTaiwan
Study dates: 25 Feb 2020to 22 Jun 2020
Phase: Interventional
Are there results?: None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages 50 to 85 years
All sexes
No healthy volunteers
Adult, Older adult

Who may be able to join

1. modified H-Y stage II-III Parkinson's disease 2. No other diseases 3. Non-demented PD 4. Non-tremor PD

Who cannot join

None

Trial locations and contacts

1 site in 1 country.

Taiwan1 site

National Taiwan University
Taipei

Other trials in Taiwan

About this study

Read the detailed description

These hypothesis would be tested by gait performance, suprapostural accuracy and relative power spectrum of EEG.

Conditions: Postural and Suprapostural Performance During Dual Tasking in Patients With Parkinson's Disease
Being tested: Weight-shifting training
Keywords: Parkinson, dual-task training, attention, electroencephalogram (EEG)

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Weight-shifting trainingBehavioural
Postural task: Participants are standing with their weak side on the force plate. During the task, they wight-shift from side to side ranging from 10 to 90 percent of their body weight.
Suprapostural task: Participants hold a tray with their arms beside the body, 90 degrees of elbow flexion. They rotate the tray left and right for 45 degrees respectively.
During their task, participants should weight-shift and rotate the tray at the same time.

Study groups in NCT04288024
Study group	Role	What they receive
Postural	Experimental	During training, participants in this group are instructed to focus on their posture during weight-shifting. Receives: Behavioral: Weight-shifting training
Suprapostural	Experimental	During training, participants in this group are instructed to focus on their suprapostural task during weight-shifting. Receives: Behavioral: Weight-shifting training

What is being measured

The primary outcome is the main question the study is designed to answer.

EEG relative power in the delta band
postural and suprapostural performance of a dual task
Measured: 60 minutes
EEG relative power in the theta band
postural and suprapostural performance of a dual task
Measured: 60 minutes
EEG relative power in the alpha band
postural and suprapostural performance of a dual task
Measured: 60 minutes
EEG relative power in the beta band
postural and suprapostural performance of a dual task
Measured: 60 minutes
EEG relative power in the gamma band
postural and suprapostural performance of a dual task
Measured: 60 minutes
COP trajectory recorded from the force plate
performance of the postural task
Measured: 60 minutes
Angles from inclinometer
performance of the suprapostural task
Measured: 60 minutes

Secondary outcomes (4)

Gait velocity from GAITRite
gait performance
Measured: 5 minutes
Cadence from GAITRite
gait performance
Measured: 5 minutes
Mean step length from GAITRite
gait performance
Measured: 5 minutes
Step-to-step variability from GAITRite
gait performance
Measured: 5 minutes

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

25 Feb 202022 Jun 2020

First posted27 Feb 2020
Study start25 Feb 2020
Primary completion22 Jun 2020
Study completion22 Jun 2020

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Other trials for Postural and Suprapostural Performance During Dual Tasking in Patients With Parkinson's DiseaseStudies of the same condition, open and under way.
More trials run by National Taiwan University HospitalThe sponsor's other registered studies.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase N/A
Primary purpose: Treatment
Allocation: Randomised
Intervention model: Parallel groups
Masking: Single blind
Who is masked: Participant
Enrolment: 28 participants (actual)

IDs, dates and publications

ClinicalTrials.gov ID: NCT04288024
Sponsor's protocol ID: 201907085RIND
Status last verified: Feb 2020
First submitted: 24 Feb 2020
Last updated: 17 Mar 2021
Results posted: No
Data monitoring committee: No
FDA-regulated drug: No
FDA-regulated device: No
Individual data sharing: No

Study at a glance

From the registry record, last updated by the sponsor on 17 Mar 2021. Recruitment status is as the sponsor reported it: confirm with the study team.

Official title: The Learning Effects of Task-priority Strategy on Dual-task Weight Shifting and Brain Plasticity in Patients With Parkinson's Disease
ClinicalTrials.gov ID: NCT04288024
Acronym / sponsor ID: 201907085RIND
Conditions: Postural and Suprapostural Performance During Dual Tasking in Patients With Parkinson's Disease
Keywords: Parkinson, dual-task training, attention, electroencephalogram (EEG)
Study type: Interventional
Recruitment status: Completed
Enrolment: 28 participants (actual)
Lead sponsor: National Taiwan University HospitalUniversity, hospital or other
Study start: 25 Feb 2020 (actual)
Primary completion: 22 Jun 2020 (actual)
Study completion: 22 Jun 2020 (actual)
First posted: 27 Feb 2020 (actual)
Results: Not posted in the source record

Clinical summary

The research question as the sponsor registered it. This describes what the study plans to test, not what it found.

Detailed description

These hypothesis would be tested by gait performance, suprapostural accuracy and relative power spectrum of EEG.

Study design

Primary purpose: Treatment
Allocation: Randomised
Intervention model: Parallel groups
Masking: Single blind (participant)
Number of arms: 2

Arm	Type	Receives
Postural	Experimental	Behavioral: Weight-shifting trainingDuring training, participants in this group are instructed to focus on their posture during weight-shifting.
Suprapostural	Experimental	Behavioral: Weight-shifting trainingDuring training, participants in this group are instructed to focus on their suprapostural task during weight-shifting.

Who may qualify

Ages: 50 to 85 years
Sex: All
Healthy volunteers: Not accepted
Age groups: Adult, Older adult

Key inclusion criteria (1 listed)

1. modified H-Y stage II-III Parkinson's disease 2. No other diseases 3. Non-demented PD 4. Non-tremor PD

Key exclusion criteria (1 listed)

None

Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.

Interventions

Intervention	Type	Arms
Weight-shifting trainingPostural task: Participants are standing with their weak side on the force plate. During the task, they wight-shift from side to side ranging from 10 to 90 percent of their body weight. Suprapostural task: Participants hold a tray with their arms beside the body, 90 degrees of elbow flexion. They rotate the tray left and right for 45 degrees respectively. During their task, participants should weight-shift and rotate the tray at the same time.	Behavioural	Postural, Suprapostural

Primary outcome

EEG relative power in the delta band
Time frame: 60 minutes
postural and suprapostural performance of a dual task
EEG relative power in the theta band
Time frame: 60 minutes
postural and suprapostural performance of a dual task
EEG relative power in the alpha band
Time frame: 60 minutes
postural and suprapostural performance of a dual task
EEG relative power in the beta band
Time frame: 60 minutes
postural and suprapostural performance of a dual task
EEG relative power in the gamma band
Time frame: 60 minutes
postural and suprapostural performance of a dual task
COP trajectory recorded from the force plate
Time frame: 60 minutes
performance of the postural task
Angles from inclinometer
Time frame: 60 minutes
performance of the suprapostural task

4 secondary outcomes

Gait velocity from GAITRite
Time frame: 5 minutes
Cadence from GAITRite
Time frame: 5 minutes
Mean step length from GAITRite
Time frame: 5 minutes
Step-to-step variability from GAITRite
Time frame: 5 minutes

Results and safety

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

Research links

Official record on ClinicalTrials.govLast updated by the sponsor 17 Mar 2021.
Individual participant dataSharing planned: No

Referral and contact

AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.

The record lists no contact. Use the official record to reach the sponsor.

1 site in 1 country: see every site and its status.

Questions about this trial

What is this clinical trial studying?

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 17 Mar 2021. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

EEG relative power in the delta band (time frame: 60 minutes). The study lists 7 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT04288024.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Mar 2021; AzTrials last refreshed its copy on 27 Oct 2026.