SatietyNCT03957928
Effects of Fresh Mango Pulp Consumption on Satiety and Cardiometabolic Health
A study testing Low fat cookie and Mango fruit in people with Satiety, run by San Diego State University at 1 site in United States.
Trial summary
The objective of the study is to determine the effects of fresh mango pulp consumption on satiety and metabolic parameters in overweight/obese adults. Read more about this study
- Who is it for?
- Ages 18 to 55 yearsHealthy volunteers can take part
- Conditions the study is for
- Satiety
- What is being tested?
- Low fat cookie and Mango fruit
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- 1 siteUnited States
- Study dates
- 1 Mar 2019to Dec 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 55 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- 18-55 years old
- BMI 27-40
Who cannot join
- Smoker
- Pregnant woman
- Required dietary supplement use
- Required medication of metabolic disorders
- Allergy to mango or gluten
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
School of Exercise and Nutritional Sciences, SDSU
San Diego, California, 92182-7251
Mee Young Hong, 619-594-2392, mhong2@mail.sdsu.edu
About this study
The objective of the study is to determine the effects of fresh mango pulp consumption on satiety and metabolic parameters in overweight/obese adults.
- Conditions
- Satiety
- Being tested
- Low fat cookie, Mango fruit
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Low fat cookieOther
to determine the effects of low fat cookie consumption on satiety and metabolic parameters in overweight/obese adults
Mango fruitOther
to determine the effects of fresh mango pulp consumption on satiety and metabolic parameters in overweight/obese adults
| Study group | Role | What they receive |
|---|---|---|
| Low fat cookies | Active comparator | Subjects consume 100 kcal of low fat cookies daily for 12 weeks. Receives: Other: Low fat cookie |
| Mango fruit | Experimental | Subjects consume 100 kcal of mango fruit daily for 12 weeks. Receives: Other: Mango fruit |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change of satiety
Change of hunger feeling (appetite) will be examined using visual analog scale (0-10): 0 least and 10 greatest
Measured: 0, 20, 40, 60, 90 and 120 minutes post snack consumption
Change of glucose level
Change of blood glucose response will be determined to examine effects of mango consumption vs low fat cookie consumption
Measured: 0, 30, 60, 90 and 120 minutes post snack consumption; baseline and week 12
Change of insulin level
Change of blood insulin level will be determined to examine effects of mango consumption vs low fat cookie consumption
Measured: 0 and 60 minutes post snack consumption, baseline and week 12
Secondary outcomes (1)
Change of microbiome
Change of microbiome diversity will be determined to examine effects of mango consumption vs low fat cookie consumption
Measured: Baseline, week 4 and week12
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted21 May 2019
- Study start1 Mar 2019
- Primary completionDec 2028 (estimated)
- Study completionDec 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for SatietyStudies of the same condition, open and under way.
- More trials run by San Diego State UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Enrolment
- 50 participants (estimated)
Sponsor and investigators
- Lead sponsor
- San Diego State University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT03957928
- Sponsor's protocol ID
- HS-2019-0034
- Status last verified
- Jan 2026
- First submitted
- 25 Apr 2019
- Last updated
- 21 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Rosas M Jr, Pinneo S, O'Mealy C, Tsang M, Liu C, Kern M, Hooshmand S, Hong MY. Effects of fresh mango consumption on cardiometabolic risk factors in overweight and obese adults. Nutr Metab Cardiovasc Dis. 2022 Feb;32(2):494-503. doi: 10.1016/j.numecd.2021.11.001. Epub 2021 Nov 12.
PubMed 34953634Pinneo S, O'Mealy C, Rosas M Jr, Tsang M, Liu C, Kern M, Hooshmand S, Hong MY. Fresh Mango Consumption Promotes Greater Satiety and Improves Postprandial Glucose and Insulin Responses in Healthy Overweight and Obese Adults. J Med Food. 2022 Apr;25(4):381-388. doi: 10.1089/jmf.2021.0063. Epub 2021 Nov 23.
PubMed 34813369
Study at a glance
From the registry record, last updated by the sponsor on 21 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Fresh Mango Pulp Consumption on Satiety and Cardiometabolic Health
- ClinicalTrials.gov ID
- NCT03957928
- Acronym / sponsor ID
- HS-2019-0034
- Conditions
- Satiety
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 50 participants (estimated)
- Lead sponsor
- San Diego State UniversityUniversity, hospital or other
- Study start
- 1 Mar 2019 (actual)
- Primary completion
- Dec 2028 (estimated)
- Study completion
- Dec 2028 (estimated)
- First posted
- 21 May 2019 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The objective of the study is to determine the effects of fresh mango pulp consumption on satiety and metabolic parameters in overweight/obese adults.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Low fat cookies | Active comparator | Other: Low fat cookieSubjects consume 100 kcal of low fat cookies daily for 12 weeks. |
| Mango fruit | Experimental | Other: Mango fruitSubjects consume 100 kcal of mango fruit daily for 12 weeks. |
Who may qualify
- Ages
- 18 to 55 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (2 listed)
- 18-55 years old
- BMI 27-40
Key exclusion criteria (5 listed)
- Smoker
- Pregnant woman
- Required dietary supplement use
- Required medication of metabolic disorders
- Allergy to mango or gluten
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Low fat cookieto determine the effects of low fat cookie consumption on satiety and metabolic parameters in overweight/obese adults | Other | Low fat cookies |
| Mango fruitto determine the effects of fresh mango pulp consumption on satiety and metabolic parameters in overweight/obese adults | Other | Mango fruit |
Primary outcome
Change of satiety
Time frame: 0, 20, 40, 60, 90 and 120 minutes post snack consumption
Change of hunger feeling (appetite) will be examined using visual analog scale (0-10): 0 least and 10 greatest
Change of glucose level
Time frame: 0, 30, 60, 90 and 120 minutes post snack consumption; baseline and week 12
Change of blood glucose response will be determined to examine effects of mango consumption vs low fat cookie consumption
Change of insulin level
Time frame: 0 and 60 minutes post snack consumption, baseline and week 12
Change of blood insulin level will be determined to examine effects of mango consumption vs low fat cookie consumption
1 secondary outcome
Change of microbiome
Time frame: Baseline, week 4 and week12
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 21 Jan 2026.
- Derived from this study: PubMed 34953634Rosas M Jr, Pinneo S, O'Mealy C, Tsang M, Liu C, Kern M, Hooshmand S, Hong MY. Effects of fresh mango consumption on cardiometabolic risk factors in overweight and obese adults. Nutr Metab Cardiovasc Dis. 2022 Feb;32(2):494-503. doi: 10.1016/j.numecd.2021.11.001. Epub 2021 Nov 12.
- Derived from this study: PubMed 34813369Pinneo S, O'Mealy C, Rosas M Jr, Tsang M, Liu C, Kern M, Hooshmand S, Hong MY. Fresh Mango Consumption Promotes Greater Satiety and Improves Postprandial Glucose and Insulin Responses in Healthy Overweight and Obese Adults. J Med Food. 2022 Apr;25(4):381-388. doi: 10.1089/jmf.2021.0063. Epub 2021 Nov 23.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Low fat cookie and Mango fruit in people with Satiety, run by San Diego State University at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 21 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Mee Young Hong (6195942392, mhong2@sdsu.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change of satiety (time frame: 0, 20, 40, 60, 90 and 120 minutes post snack consumption). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT03957928, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 21 Jan 2026.