Pediatric HealthNCT03351595
Ewha Birth and Growth Study (Birth Cohort)
An observational study of Pediatric Health and Growth & Development, run by Ewha Womans University at 1 site in South Korea.
Trial summary
The Ewha Birth and Growth Study is a prospective birth cohort established at Ewha Womans University Mokdong Hospital in Seoul, Republic of Korea. Pregnant women were recruited between 2001 and 2006, and their offspring were followed longitudinally from birth through childhood, adolescence, and young adulthood. Read more about this study
- Who is it for?
- Any ageHealthy volunteers can take part
- Conditions the study is for
- Pediatric Health, Growth & Development, Cardiometabolic Health
- How many people
- 940 participants
- Where
- 1 siteSouth Korea
- Study dates
- Sep 2001to Aug 2026
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Study population: Pregnant women recruited during prenatal care and their offspring followed longitudinally from birth through young adulthood.
Who may be able to join
- Pregnant women who received prenatal care between 24 and 28 weeks of gestation and were enrolled between 2001 and 2006.
- Individuals who could participate in scheduled follow-up examinations and comply with the study requirements.
Who cannot join
- Individuals considered unable to participate in the study procedures for other reasons, based on the investigator's judgement.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Evaluation of Influencing Factors Affecting Childhood Metabolic Indicators in Korea (Repeated Measures Analysis; Longitudinal Birth Study)
The Ewha Birth and Growth Study is a prospective birth cohort established at Ewha Womans University Mokdong Hospital in Seoul, Republic of Korea. Pregnant women were recruited between 2001 and 2006, and their offspring were followed longitudinally from birth through childhood, adolescence, and young adulthood.
Read the detailed description
The cohort was composed of mothers who received prenatal care between 24 and 28 weeks of gestation and were recruited between 2001 and 2006. After delivery, information on birth outcomes was collected, and mail surveys were conducted when the offspring were 6, 12, 18, and 24 months of age.
Regular follow-up examinations were conducted at 3 and 5 years of age, annually from 7 through 12 years of age, and once during adolescence at 13 to 15 years of age. Follow-up examinations continued into young adulthood, with an examination at 19 years of age.
During follow-up examinations, after an 8-hour overnight fast, blood samples (3 mL EDTA blood and 5 mL serum) were obtained from participants by venipuncture, and urine samples were collected. Assessments included physical growth, blood pressure, metabolic biomarkers, dietary intake, psychological and behavioral measures, socioeconomic status, physical activity, and other health-related factors.
- Keywords
- Growth pattern, Environmental and prenatal exposure, Birth cohort, Longitudinal study, Life-course approach
What is being measured
The primary outcome is the main question the study is designed to answer.
Physical growth assessed by anthropometric measurements
Anthropometric measurements were obtained during scheduled follow-up examinations to assess longitudinal physical growth. Participants received individualized health examination results following the assessments.
Measured: At 3 and 5 years of age; annually from 7 through 12 years of age; at 13 to 15 years of age; and at 19 years of age
Secondary outcomes (2)
Blood pressure assessed during follow-up examinations
Systolic and diastolic blood pressure were measured during scheduled follow-up examinations.
Measured: At 3 and 5 years of age; annually from 7 through 12 years of age; at 13 to 15 years of age; and at 19 years of age
Metabolic biomarkers assessed during follow-up examinations
Fasting blood samples were collected during scheduled follow-up examinations to assess metabolic biomarkers, including total cholesterol, HDL cholesterol, triglycerides, glucose, uric acid, and other metabolic biomarkers.
Measured: At 3 and 5 years of age; annually from 7 through 12 years of age; at 13 to 15 years of age; and at 19 years of age
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Nov 2017
- Study startSep 2001
- Primary completionAug 2026
- Study completionAug 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Pediatric HealthStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 940 participants (actual)
Sponsor and investigators
- Lead sponsor
- Ewha Womans University
- Sponsor type
- University, hospital or other
- Collaborators
- National Research Foundation of Korea
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT03351595
- Sponsor's protocol ID
- EWCS
- Status last verified
- Sep 2026
- First submitted
- 18 Oct 2017
- Last updated
- 21 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Publications
Lee HA, Park B, Min J, Choi EJ, Kim UJ, Park HJ, Park EA, Cho SJ, Kim HS, Lee H, Kim YJ, Hong YS, Kim EJ, Ha EH, Park H. Cohort profile: the Ewha Birth and Growth Study. Epidemiol Health. 2021;43:e2021016. doi: 10.4178/epih.e2021016. Epub 2021 Feb 22.
PubMed 33677859
Study at a glance
From the registry record, last updated by the sponsor on 21 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Evaluation of Influencing Factors Affecting Childhood Metabolic Indicators in Korea (Repeated Measures Analysis; Longitudinal Birth Study)
- ClinicalTrials.gov ID
- NCT03351595
- Acronym / sponsor ID
- EWCS
- Keywords
- Growth pattern, Environmental and prenatal exposure, Birth cohort, Longitudinal study, Life-course approach
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 940 participants (actual)
- Lead sponsor
- Ewha Womans UniversityUniversity, hospital or other
- Collaborators
- National Research Foundation of Korea
- Study start
- Sep 2001 (actual)
- Primary completion
- Aug 2026 (actual)
- Study completion
- Aug 2026 (actual)
- First posted
- 24 Nov 2017 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The Ewha Birth and Growth Study is a prospective birth cohort established at Ewha Womans University Mokdong Hospital in Seoul, Republic of Korea. Pregnant women were recruited between 2001 and 2006, and their offspring were followed longitudinally from birth through childhood, adolescence, and young adulthood.
Detailed description
The cohort was composed of mothers who received prenatal care between 24 and 28 weeks of gestation and were recruited between 2001 and 2006. After delivery, information on birth outcomes was collected, and mail surveys were conducted when the offspring were 6, 12, 18, and 24 months of age.
Regular follow-up examinations were conducted at 3 and 5 years of age, annually from 7 through 12 years of age, and once during adolescence at 13 to 15 years of age. Follow-up examinations continued into young adulthood, with an examination at 19 years of age.
During follow-up examinations, after an 8-hour overnight fast, blood samples (3 mL EDTA blood and 5 mL serum) were obtained from participants by venipuncture, and urine samples were collected. Assessments included physical growth, blood pressure, metabolic biomarkers, dietary intake, psychological and behavioral measures, socioeconomic status, physical activity, and other health-related factors.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
- Study population
- Pregnant women recruited during prenatal care and their offspring followed longitudinally from birth through young adulthood.
Key inclusion criteria (2 listed)
- Pregnant women who received prenatal care between 24 and 28 weeks of gestation and were enrolled between 2001 and 2006.
- Individuals who could participate in scheduled follow-up examinations and comply with the study requirements.
Key exclusion criteria (1 listed)
- Individuals considered unable to participate in the study procedures for other reasons, based on the investigator's judgement.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Physical growth assessed by anthropometric measurements
Time frame: At 3 and 5 years of age; annually from 7 through 12 years of age; at 13 to 15 years of age; and at 19 years of age
Anthropometric measurements were obtained during scheduled follow-up examinations to assess longitudinal physical growth. Participants received individualized health examination results following the assessments.
2 secondary outcomes
Blood pressure assessed during follow-up examinations
Time frame: At 3 and 5 years of age; annually from 7 through 12 years of age; at 13 to 15 years of age; and at 19 years of age
Metabolic biomarkers assessed during follow-up examinations
Time frame: At 3 and 5 years of age; annually from 7 through 12 years of age; at 13 to 15 years of age; and at 19 years of age
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 21 Sep 2026.
- Results publication: PubMed 33677859Lee HA, Park B, Min J, Choi EJ, Kim UJ, Park HJ, Park EA, Cho SJ, Kim HS, Lee H, Kim YJ, Hong YS, Kim EJ, Ha EH, Park H. Cohort profile: the Ewha Birth and Growth Study. Epidemiol Health. 2021;43:e2021016. doi: 10.4178/epih.e2021016. Epub 2021 Feb 22.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Pediatric Health and Growth & Development, run by Ewha Womans University at 1 site in South Korea.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 21 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in South Korea. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Physical growth assessed by anthropometric measurements (time frame: At 3 and 5 years of age; annually from 7 through 12 years of age; at 13 to 15 years of age; and at 19 years of age). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT03351595, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 21 Sep 2026.