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AzTrials

MalnutritionNHERCNCT03240952

The Nutritional Health for the Elderly Reference Centre Study (NHERC Study)

An observational study of Malnutrition, run by Abbott Nutrition at 4 sites in Singapore.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

Elderly are at greater risk of dietary insufficiency due to age-related increases in nutrient requirements concomitant with a reduction in energy requirements, decreases in appetite and energy intake. Read more about this study

Who is it for?
Ages 65 to 110 yearsHealthy volunteers can take part
Conditions the study is for
Malnutrition
How many people
400 participants
Where
4 sitesSingapore
Study dates
30 Aug 2017to 26 Jul 2018
Phase
Observational
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 65 to 110 years
  • All sexes
  • Healthy volunteers accepted
  • Older adult

Study population: This cross-sectional study will include 400 elderly with normal nutrition (MUST score: 0) and 800 elderly who are at risk of undernutrition (MUST score ≥ 1). Community-dwelling elderly recently discharged from the hospital as well as those who recently visited polyclinics in Singapore will be recruited for the study.

Who may be able to join

  • Male or female participant aged ≥65 years.
  • Community-dweller, i.e. not staying in a residential intermediate and long-term care (ILTC) service institution.
  • Participant is being discharged home directly (applicable for hospital cohort).
  • Participant is community ambulant with or without aid.
  • Participant does not have any chronic disease(s) or has stable chronic disease(s) including hypertension, chronic obstructive pulmonary disease, and cardiovascular disease in the opinion of the Study Physician, at study entry.
  • Participant has voluntarily signed and dated an informed consent form (ICF), approved by an Institutional Review Board (IRB) and provided authorization prior to any participation in the study.
  • Participants will be able to communicate and follow instructions.
  • Participant is able to consume food and beverages orally.

Who cannot join

  • Participant has been diagnosed with dementia according to medical records.
  • Participant has been diagnosed with type 1 or type 2 diabetes according to medical records. (Note: This includes participant with controlled diabetes.)
  • Participant has any active infectious disease (such as tuberculosis, Hepatitis B or C, HIV infection) according to medical records.
  • Participant has been diagnosed with severe gastrointestinal disorders including celiac disease, short bowel syndrome, pancreatic insufficiency, or cystic fibrosis according to medical records.
  • Participant has been diagnosed with end stage organ or pre-terminal diseases or acute myocardial infarction within the last 30 days from the screening according to medical records.
  • Participant has malignancy according to medical records.
  • Participant has any other clinically significant medical condition, which in the investigator's opinion, makes him or her unsuitable for inclusion in the study.
  • Participant is taking part in another study that has not been approved as a concomitant study by the study team.

Trial locations and contacts

4 sites in 1 country.

Singapore4 sites

  • Marine Parade Polyclinic

    Singapore, 440080

  • Bedok Polyclinic

    Singapore, 460212

  • Tampines Polyclinic

    Singapore, 529203

  • Changi General Hospital

    Singapore, 529889

Other trials in Singapore

About this study

Official title: Establishing Reference Range for Community-dwelling Elderly Nutrition

Elderly are at greater risk of dietary insufficiency due to age-related increases in nutrient requirements concomitant with a reduction in energy requirements, decreases in appetite and energy intake. Currently there is a gap in knowledge of the factors that are associated with malnutrition in the elderly in Singapore. In addition, there is no "reference" database on anthropometric measurements and biochemical indices for elderly with a range of nutrition status in Singapore. Thus, the objectives of this cross-sectional study are to examine factors influencing nutritional status and to determine the reference values for anthropometric and biochemical measurements related to nutritional status for community-dwelling elderly in Singapore.

Read the detailed description

This is a cross-sectional study. Measurements will be taken at baseline for elderly with normal nutrition (n = 400) and elderly who are at risk of under nutrition (n = 800).. These measurements will be used to examine factors influencing nutritional status and to create a "reference" database for anthropometric and biochemical measurements related to nutritional status for use in clinical practice.

Conditions
Malnutrition
Medical subject headings
Malnutrition

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. MUST

    Malnutrition risk using Malnutrition Universal Screening Tool

    Measured: Baseline

Secondary outcomes (3)

  1. Body weight, fat mass, fat free mass

    Body weight, fat mass, fat free mass in kilograms will be measured using Tanita MC-780

    Measured: Baseline

  2. Pre-albumin

    Pre-albumin in mg/dL will be measured using Cobas

    Measured: Baseline

  3. Albumin and total protein

    Albumin and total protein in g/L will be measured using Cobas

    Measured: Baseline

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted7 Aug 2017
  2. Study start30 Aug 2017
  3. Primary completion28 May 2018
  4. Study completion26 Jul 2018

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Observational model
Cohort
Time perspective
Cross-sectional
Enrolment
400 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT03240952
Sponsor's protocol ID
BL35 (Part 1)
Acronym
NHERC
Status last verified
Apr 2020
First submitted
1 Aug 2017
Last updated
15 Apr 2020
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No

Publications

  • Husain FS, Tey SL, Huynh DTT, Oliver J, Baggs G, How CH, Chow WL, Cheong M, Aw TC, Chew STH, Tan NC. Aging and liver health: liver chemistries and associated factors in community-dwelling older adults. BMC Geriatr. 2025 Aug 23;25(1):658. doi: 10.1186/s12877-025-06329-2.

    PubMed 40849644

  • Ong RHS, Chow WL, Cheong M, Lim GH, Xie W, Baggs G, Huynh DTT, Oh HC, How CH, Tan NC, Tey SL, Chew STH. Associations between socio-demographics, nutrition knowledge, nutrition competencies and attitudes in community-dwelling healthy older adults in Singapore: findings from the SHIELD study. J Health Popul Nutr. 2021 Dec 11;40(1):52. doi: 10.1186/s41043-021-00277-4.

    PubMed 34895351

Questions about this trial

What is this clinical trial studying?

An observational study of Malnutrition, run by Abbott Nutrition at 4 sites in Singapore.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 8 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 15 Apr 2020. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 4 sites in Singapore. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

MUST (time frame: Baseline). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT03240952, which also lists 2 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Apr 2020.

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