Allergic RhinitisNCT03101618
Animal Allergy in Korean Pet Owners, Pet-related Industry Workers, and Laboratory Animal Reseachers
An observational study of Allergic Rhinitis and Allergic Conjunctivitis, run by Gachon University Gil Medical Center at 1 site in South Korea.
Trial summary
The investigators surveyed the prevalence of animal allergy and sensitization to animal allergen among participants in international symposium of Korean association for laboratory science (laboratory animal researchers) and companion animal exhibition (pet owner and pet-related industry workers). Read more about this study
- Who is it for?
- Ages 19 years and olderHealthy volunteers can take part
- Conditions the study is for
- Allergic Rhinitis, Allergic Conjunctivitis, Urticaria
- What is being tested?
- Animal allergy and Non-animal allergy
- How many people
- 643 participants
- Where
- 1 siteSouth Korea
- Study dates
- 24 Aug 2016to 27 Nov 2016
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 19 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Participants in international symposium of Korean association for laboratory science and companion animal exhibition
Who may be able to join
- Participants in international symposium of Korean association for laboratory science and companion animal exhibition from whom informed consents were obtained.
Who cannot join
- Subjects who reject enrollment into this study.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: The Prevalence of Animal Allergy and Sensitization to Animal Allergen Among Participants in International Symposium of Korean Association for Laboratory Science and Companion Animal Exhibition
The investigators surveyed the prevalence of animal allergy and sensitization to animal allergen among participants in international symposium of Korean association for laboratory science (laboratory animal researchers) and companion animal exhibition (pet owner and pet-related industry workers).
Read the detailed description
The investigators enrolled participants in international symposium of Korean association for laboratory science (laboratory animal researchers) and pet animal exhibition (pet owner and pet-related industry workers) after informed consents. Subjects were asked to response to questionnaires regarding their age, gender, comorbid allergic disease, family history of allergy, pet or laboratory animal, exposure time, allergic symptoms during exposure to animals. Subjects underwent skin prick test with animal allergens and other inhalant allergens.
- Conditions
- Allergic Rhinitis, Allergic Conjunctivitis, Urticaria, Asthma
- Being tested
- Animal allergy, Non-animal allergy
- Keywords
- allergen, allergy, pet
- Medical subject headings
- Rhinitis, Allergic, Conjunctivitis, Allergic, Urticaria, Asthma, Hypersensitivity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Animal allergyOther
Allergic symptom occurs during exposure to laboratory or pet animal
Non-animal allergyOther
Allergic symptom does not occur during exposure to laboratory or pet animal
| Study group | Role | What they receive |
|---|---|---|
| Allergic LAR | Laboratory animal researchers who experienced allergic symptom during exposure to laboratory or pet animals Receives: Other: Animal allergy | |
| Non-allergic LAR | Laboratory animal researchers who did not experience allergic symptom during exposure to laboratory or pet animals Receives: Other: Non-animal allergy | |
| Allergic PO | Pet owners who experienced allergic symptom during exposure to pet animals Receives: Other: Animal allergy | |
| Non-allergic PO | Pet owners who did not experience allergic symptom during exposure to pet animals Receives: Other: Non-animal allergy | |
| Allergic PIW | Allergic pet-related industry workers who experienced allergic symptom during exposure to pet animals Receives: Other: Animal allergy | |
| Non-allergic PIW | Allergic pet-related industry workers who did not experience allergic symptom during exposure to pet animals Receives: Other: Non-animal allergy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Skin reactivity to animal allergens
Positivity to animal allergens in skin prick test
Measured: The day of survey
Secondary outcomes (12)
Skin reactivity to other inhalant allergens
Positivity to other inhalant allergens in skin prick test
Measured: The day of survey
The prevalance of cormobid allergy
The prevalance of allergic rhinitis, allergic conjunctivitis, asthma, urticaria, atopic dermatitis, contact dermatitis, food allergy, drug allergy
Measured: The day of survey
Duration of animal exposure
Duration of laboratory or pet animal exposure (months)
Measured: The day of survey
Animal contact time
Animal contact time including direct contact and spatial sharing (min/day)
Measured: The day of survey
Residence of animal
Residence of animal (cage, bedroom, not bedroom but at home, outside)
Measured: The day of survey
Site of animal defecation
Site of animal defecation (outside, predetermined place at home, anywhere at home)
Measured: The day of survey
Laboratory or pet animal
Laboratory or pet animal which subject contacts
Measured: The day of survey
Severity of allergic symptom
Severity of allergic symptom (using visual analog scale) during exposure to animal
Measured: The day of survey
Duration of allergic symptom
Duration of allergic symptom during exposure to animal (min)
Measured: The day of survey
Frequency of house cleaning, bed cleansing, animal haircut, and animal hair removal from their garmet
Frequency of house cleaning, bed cleansing, animal haircut, and animal hair removal from their garmet in pet owners and pet-related industry workers
Measured: The day of survey
Use of medical service
Use of medical service including prescription and immunotherapy for animal allergy
Measured: The day of survey
Perception of animal allergy, its avoidance and immunotherapy
Agreement score (visual analog scale) to "Allergic symptom occurs during exposure to animal", "Avoidance can reduce or prevent from allergic symptom", "Immunotherapy can mitigate allergic symptom during exposure to animal"
Measured: The day of survey
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Apr 2017
- Study start24 Aug 2016
- Primary completion27 Nov 2016
- Study completion27 Nov 2016
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for Allergic RhinitisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Enrolment
- 643 participants (actual)
Sponsor and investigators
- Lead sponsor
- Gachon University Gil Medical Center
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Sangmin Lee, MD, Gachon University Gil Medical Center
- Investigators
- Sang Pyo Lee, MD, Study chair, Gachon University Gil Medical Center
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT03101618
- Sponsor's protocol ID
- GBIRB2016-155
- Status last verified
- Feb 2021
- First submitted
- 29 Mar 2017
- Last updated
- 3 Feb 2021
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Park YB, Mo EK, Lee JY, Kim JH, Kim CH, Hyun IG, Choi JH. Association between pet ownership and the sensitization to pet allergens in adults with various allergic diseases. Allergy Asthma Immunol Res. 2013 Sep;5(5):295-300. doi: 10.4168/aair.2013.5.5.295. Epub 2013 Jun 25.
PubMed 24003386Moghtaderi M, Farjadian S, Abbaszadeh Hasiri M. Animal allergen sensitization in veterinarians and laboratory animal workers. Occup Med (Lond). 2014 Oct;64(7):516-20. doi: 10.1093/occmed/kqu097. Epub 2014 Aug 7.
PubMed 25104279Krakowiak A, Wiszniewska M, Krawczyk P, Szulc B, Wittczak T, Walusiak J, Palczynski C. Risk factors associated with airway allergic diseases from exposure to laboratory animal allergens among veterinarians. Int Arch Occup Environ Health. 2007 May;80(6):465-75. doi: 10.1007/s00420-006-0153-0. Epub 2006 Oct 5.
PubMed 17021840
Study at a glance
From the registry record, last updated by the sponsor on 3 Feb 2021. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Prevalence of Animal Allergy and Sensitization to Animal Allergen Among Participants in International Symposium of Korean Association for Laboratory Science and Companion Animal Exhibition
- ClinicalTrials.gov ID
- NCT03101618
- Acronym / sponsor ID
- GBIRB2016-155
- Conditions
- Allergic Rhinitis, Allergic Conjunctivitis, Urticaria, Asthma
- Keywords
- allergen, allergy, pet
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 643 participants (actual)
- Lead sponsor
- Gachon University Gil Medical CenterUniversity, hospital or other
- Study start
- 24 Aug 2016 (actual)
- Primary completion
- 27 Nov 2016 (actual)
- Study completion
- 27 Nov 2016 (actual)
- First posted
- 5 Apr 2017 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The investigators surveyed the prevalence of animal allergy and sensitization to animal allergen among participants in international symposium of Korean association for laboratory science (laboratory animal researchers) and companion animal exhibition (pet owner and pet-related industry workers).
Detailed description
The investigators enrolled participants in international symposium of Korean association for laboratory science (laboratory animal researchers) and pet animal exhibition (pet owner and pet-related industry workers) after informed consents. Subjects were asked to response to questionnaires regarding their age, gender, comorbid allergic disease, family history of allergy, pet or laboratory animal, exposure time, allergic symptoms during exposure to animals. Subjects underwent skin prick test with animal allergens and other inhalant allergens.
Study design
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Number of arms
- 6
| Arm | Type | Receives |
|---|---|---|
| Allergic LAR | – | Other: Animal allergyLaboratory animal researchers who experienced allergic symptom during exposure to laboratory or pet animals |
| Non-allergic LAR | – | Other: Non-animal allergyLaboratory animal researchers who did not experience allergic symptom during exposure to laboratory or pet animals |
| Allergic PO | – | Other: Animal allergyPet owners who experienced allergic symptom during exposure to pet animals |
| Non-allergic PO | – | Other: Non-animal allergyPet owners who did not experience allergic symptom during exposure to pet animals |
| Allergic PIW | – | Other: Animal allergyAllergic pet-related industry workers who experienced allergic symptom during exposure to pet animals |
| Non-allergic PIW | – | Other: Non-animal allergyAllergic pet-related industry workers who did not experience allergic symptom during exposure to pet animals |
Who may qualify
- Ages
- 19 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Participants in international symposium of Korean association for laboratory science and companion animal exhibition
Key inclusion criteria (1 listed)
- Participants in international symposium of Korean association for laboratory science and companion animal exhibition from whom informed consents were obtained.
Key exclusion criteria (1 listed)
- Subjects who reject enrollment into this study.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Animal allergyAllergic symptom occurs during exposure to laboratory or pet animal | Other | Allergic LAR, Allergic PIW, Allergic PO |
| Non-animal allergyAllergic symptom does not occur during exposure to laboratory or pet animal | Other | Non-allergic LAR, Non-allergic PIW, Non-allergic PO |
Primary outcome
Skin reactivity to animal allergens
Time frame: The day of survey
Positivity to animal allergens in skin prick test
12 secondary outcomes
Skin reactivity to other inhalant allergens
Time frame: The day of survey
The prevalance of cormobid allergy
Time frame: The day of survey
Duration of animal exposure
Time frame: The day of survey
Animal contact time
Time frame: The day of survey
Residence of animal
Time frame: The day of survey
Site of animal defecation
Time frame: The day of survey
Laboratory or pet animal
Time frame: The day of survey
Severity of allergic symptom
Time frame: The day of survey
Duration of allergic symptom
Time frame: The day of survey
Frequency of house cleaning, bed cleansing, animal haircut, and animal hair removal from their garmet
Time frame: The day of survey
Use of medical service
Time frame: The day of survey
Perception of animal allergy, its avoidance and immunotherapy
Time frame: The day of survey
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Feb 2021.
- Background: PubMed 24003386Park YB, Mo EK, Lee JY, Kim JH, Kim CH, Hyun IG, Choi JH. Association between pet ownership and the sensitization to pet allergens in adults with various allergic diseases. Allergy Asthma Immunol Res. 2013 Sep;5(5):295-300. doi: 10.4168/aair.2013.5.5.295. Epub 2013 Jun 25.
- Results publication: PubMed 25104279Moghtaderi M, Farjadian S, Abbaszadeh Hasiri M. Animal allergen sensitization in veterinarians and laboratory animal workers. Occup Med (Lond). 2014 Oct;64(7):516-20. doi: 10.1093/occmed/kqu097. Epub 2014 Aug 7.
- Results publication: PubMed 17021840Krakowiak A, Wiszniewska M, Krawczyk P, Szulc B, Wittczak T, Walusiak J, Palczynski C. Risk factors associated with airway allergic diseases from exposure to laboratory animal allergens among veterinarians. Int Arch Occup Environ Health. 2007 May;80(6):465-75. doi: 10.1007/s00420-006-0153-0. Epub 2006 Oct 5.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Sang Pyo Lee, MD study chair
Gachon University Gil Medical Center
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Allergic Rhinitis and Allergic Conjunctivitis, run by Gachon University Gil Medical Center at 1 site in South Korea.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 3 Feb 2021. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in South Korea. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Skin reactivity to animal allergens (time frame: The day of survey). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT03101618, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Feb 2021.