Insulin SensitivityNCT02913079
The Acute Impact of Sit-stand Desks on Post-meal Blood Sugar Levels
A study testing Sit-stand desk and Sitting desk in people with Insulin Sensitivity and Glucose Tolerance, run by University of Prince Edward Island at 1 site in Canada.
Trial summary
Context and Rationale: Uninterrupted sitting is associated with increased risk of diabetes, heart disease, and death, even among people who are physically active. These relationships are likely due to increases in post-meal blood sugar observed when people sit for long periods (e.g. > 1 hour) without interruption. Read more about this study
- Who is it for?
- Ages 20 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- Insulin Sensitivity, Glucose Tolerance, Sedentary Behaviour
- What is being tested?
- Sit-stand desk and Sitting desk
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 14 participants
- Where
- 1 siteCanada
- Study dates
- Sep 2016to Sep 2018
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- To participate in this study, participants must be between the ages of 20 and 65, and have access to a sit-stand desk (depending on your workspace, we may be able to provide you with a sit-stand desk during the study if you do not already have one).
Who cannot join
- Participants will be excluded if they are currently taking any diabetes medications targeting blood sugar or insulin sensitivity as this will impact our primary outcome of postprandial glucose. Participants will also be excluded if they are unable to stand or walk independently, as these are secondary outcomes in the present study.
Trial locations and contacts
1 site in 1 country.
Canada1 site
University of Prince Edward Island
Charlottetown, Prince Edward Island, C1A 4P3
About this study
Context and Rationale: Uninterrupted sitting is associated with increased risk of diabetes, heart disease, and death, even among people who are physically active. These relationships are likely due to increases in post-meal blood sugar observed when people sit for long periods (e.g. > 1 hour) without interruption. In contrast to sitting, standing results in large reductions in post-meal blood sugar levels. Our group has recently shown that sit-stand desks result in large (e.g. 2.5 hour/day) reductions in occupational sitting time. Taken together, these findings suggest that sit-stand desks may help to reduce post-meal blood sugar levels. However, this has yet to be examined in the field. Theoretical Approach and Objectives: The objective of this randomized crossover study is to determine whether people have lower blood sugar when using a sit-stand desk, in comparison to a desk that can only be used while sitting. Methods and Procedures: Sixteen participants will be asked to wear a continuous glucose monitor to measure their blood sugar levels during 2 separate conditions. During one condition, they will be asked to use a sit-stand desk to sit and/or stand as much as they like during 1 workday. During the other condition, they will be asked to work at a seated desk for 1 workday. Participants will be provided with identical meals to eat during each of the two conditions. We hypothesize that participants will have lower blood sugar levels on the day when they use the sit-stand desk, in comparison to the day using a traditional seated desk. Significance and Future Use: If our results support this hypothesis, this would suggest that sit-stand desks may be a useful way to reduce blood sugar levels in people at risk for diabetes. This could also lead to larger population-based interventions studying the health impact of sit-stand desks.
- Being tested
- Sit-stand desk, Sitting desk
- Medical subject headings
- Insulin Resistance, Motor Activity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Sit-stand deskBehavioural
Sitting deskBehavioural
| Study group | Role | What they receive |
|---|---|---|
| Sit-stand desk | Experimental | During this condition, participants will sit or stand as much as they like throughout a workday. Receives: Behavioral: Sit-stand desk |
| Sitting | Placebo comparator | During this condition, participants will work in the sitting position only. Receives: Behavioral: Sitting desk |
What is being measured
The primary outcome is the main question the study is designed to answer.
Postprandial Glucose
Postprandial glucose will be assessed over 1 workday in both the experimental and control conditions.
Measured: 12 hours
Secondary outcomes (2)
Objectively measured minutes of light, moderate and vigorous physical activity.
Physical activity time will be assessed over 1 workday during both conditions.
Measured: 24 hours
Objectively measured minutes of sitting
Sitting time will be assessed over 1 workday during both conditions.
Measured: 24 hours
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Sep 2016 (estimated)
- Study startSep 2016
- Primary completionJun 2018
- Study completionSep 2018
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Insulin SensitivityStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Enrolment
- 14 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Prince Edward Island
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Travis Saunders, University of Prince Edward Island
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT02913079
- Sponsor's protocol ID
- 6006774
- Status last verified
- Oct 2018
- First submitted
- 15 Sep 2016
- Last updated
- 17 Oct 2018
- Results posted
- No
- Data monitoring committee
- No
- Individual data sharing
- No: No.
Study at a glance
From the registry record, last updated by the sponsor on 17 Oct 2018. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Acute Impact of Sit-stand Desks on Post-meal Blood Sugar Levels
- ClinicalTrials.gov ID
- NCT02913079
- Acronym / sponsor ID
- 6006774
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 14 participants (actual)
- Lead sponsor
- University of Prince Edward IslandUniversity, hospital or other
- Study start
- Sep 2016
- Primary completion
- Jun 2018 (actual)
- Study completion
- Sep 2018 (actual)
- First posted
- 23 Sep 2016 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Context and Rationale: Uninterrupted sitting is associated with increased risk of diabetes, heart disease, and death, even among people who are physically active. These relationships are likely due to increases in post-meal blood sugar observed when people sit for long periods (e.g. > 1 hour) without interruption. In contrast to sitting, standing results in large reductions in post-meal blood sugar levels. Our group has recently shown that sit-stand desks result in large (e.g. 2.5 hour/day) reductions in occupational sitting time. Taken together, these findings suggest that sit-stand desks may help to reduce post-meal blood sugar levels. However, this has yet to be examined in the field. Theoretical Approach and Objectives: The objective of this randomized crossover study is to determine whether people have lower blood sugar when using a sit-stand desk, in comparison to a desk that can only be used while sitting. Methods and Procedures: Sixteen participants will be asked to wear a continuous glucose monitor to measure their blood sugar levels during 2 separate conditions. During one condition, they will be asked to use a sit-stand desk to sit and/or stand as much as they like during 1 workday. During the other condition, they will be asked to work at a seated desk for 1 workday. Participants will be provided with identical meals to eat during each of the two conditions. We hypothesize that participants will have lower blood sugar levels on the day when they use the sit-stand desk, in comparison to the day using a traditional seated desk. Significance and Future Use: If our results support this hypothesis, this would suggest that sit-stand desks may be a useful way to reduce blood sugar levels in people at risk for diabetes. This could also lead to larger population-based interventions studying the health impact of sit-stand desks.
Study design
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Sit-stand desk | Experimental | Behavioral: Sit-stand deskDuring this condition, participants will sit or stand as much as they like throughout a workday. |
| Sitting | Placebo comparator | Behavioral: Sitting deskDuring this condition, participants will work in the sitting position only. |
Who may qualify
- Ages
- 20 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- To participate in this study, participants must be between the ages of 20 and 65, and have access to a sit-stand desk (depending on your workspace, we may be able to provide you with a sit-stand desk during the study if you do not already have one).
Key exclusion criteria (1 listed)
- Participants will be excluded if they are currently taking any diabetes medications targeting blood sugar or insulin sensitivity as this will impact our primary outcome of postprandial glucose. Participants will also be excluded if they are unable to stand or walk independently, as these are secondary outcomes in the present study.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Sit-stand desk | Behavioural | Sit-stand desk |
| Sitting desk | Behavioural | Sitting |
Primary outcome
Postprandial Glucose
Time frame: 12 hours
Postprandial glucose will be assessed over 1 workday in both the experimental and control conditions.
2 secondary outcomes
Objectively measured minutes of light, moderate and vigorous physical activity.
Time frame: 24 hours
Objectively measured minutes of sitting
Time frame: 24 hours
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Oct 2018.
- Individual participant dataSharing planned: No. No.
Related trials for Insulin Sensitivity
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Clinical Research Trial to Study Insulin Sensitivity Using Automated Glucose Clamp Technology
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Sit-stand desk and Sitting desk in people with Insulin Sensitivity and Glucose Tolerance, run by University of Prince Edward Island at 1 site in Canada.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 17 Oct 2018. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Canada. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Postprandial Glucose (time frame: 12 hours). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Oct 2018.