HealthyBiobankNCT02804269
Molecular and Imaging Studies of Cardiovascular Health and Disease
An observational study of Healthy and Dilated Cardiomyopathy, run by National Heart Centre Singapore at 1 site in Singapore.
Trial summary
Biobank is a program which collects biological samples, health information and imaging data from consented patients and stored them at the core facility. These information would be used to study the molecular, imaging and outcome studies of cardiovascular health and disease. Read more about this study
- Who is it for?
- Ages 16 to 90 yearsHealthy volunteers can take part
- Conditions the study is for
- Healthy, Dilated Cardiomyopathy, Hypertrophic Cardiomyopathy
- What is being tested?
- Cardiovascular Magnetic Resonance and Fatmass measurement
- How many people
- 5,000 participants
- Where
- 1 siteSingapore
- Study dates
- Jul 2013to Jul 2033
- Phase
- Observational
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 16 to 90 years
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Study population: Patient will be recruited from primary care clinic and outpatient clinics from the National Heart Centre Singapore. For healthy volunteer, they will be recruited through poster and advertisement.
Who may be able to join
- •Subject aged ≥ 16 years and ≤ 90 years.
Who cannot join
- •No
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Stuart Cook, MBBS, PhD contact
Singapore1 site, 1 recruiting
- Recruiting
National Heart Centre Singapore
Singapore, Singapore, 169609
About this study
Biobank is a program which collects biological samples, health information and imaging data from consented patients and stored them at the core facility. These information would be used to study the molecular, imaging and outcome studies of cardiovascular health and disease.
Read the detailed description
This program recruits patient from National Heart Centre Singapore and collects their biological sample, health information and imaging data.The donated biospecimens will be stored indefinitely and used for any future research on molecular, imaging and outcome studies of cardiovascular health and disease.The same biological samples and imaging data will be obtained from consented healthy volunteers for comparison.
- Being tested
- Cardiovascular Magnetic Resonance, Fatmass measurement
- Keywords
- Healthy Volunteer, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, ischemic heart disease, Cardiovascular Magnetic Resonance Imaging
- Medical subject headings
- Cardiomyopathy, Dilated, Cardiomyopathy, Hypertrophic, Myocardial Ischemia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Cardiovascular Magnetic ResonanceOther
For the evaluation of heart function and structure of the cardiovascular system.
Fatmass measurementOther
It utilizes a scale machine to measure the body fat and skeletal muscle percentage
| Study group | Role | What they receive |
|---|---|---|
| Healthy Volunteer | Subjects will undergo the following study procedure: Cardiovascular Magnetic Resonance Imaging and fatmass measurement Receives: Other: Cardiovascular Magnetic Resonance; Other: Fatmass measurement | |
| Dilated Cardiomyopathy | Subjects will undergo the following study procedure: Cardiovascular Magnetic Resonance Imaging and fatmass measurement Receives: Other: Cardiovascular Magnetic Resonance; Other: Fatmass measurement | |
| Hypertrophic cardiomyopathy | Subjects will undergo the following study procedure: Cardiovascular Magnetic Resonance Imaging and fatmass measurement Receives: Other: Cardiovascular Magnetic Resonance; Other: Fatmass measurement | |
| Ischemic heart disease with reduced EF | Subjects will undergo the following study procedure: Cardiovascular Magnetic Resonance Imaging and fatmass measurement Receives: Other: Cardiovascular Magnetic Resonance; Other: Fatmass measurement | |
| Ischemic heart disease with normal EF | Subjects will undergo the following study procedure: Cardiovascular Magnetic Resonance Imaging and fatmass measurement Receives: Other: Cardiovascular Magnetic Resonance; Other: Fatmass measurement |
What is being measured
The primary outcome is the main question the study is designed to answer.
Numbers of genetic variation in genes known to cause inherited cardiac condition and circulating biomarkers which are linked with DNA changes using advanced sequencing and informatics approaches
Measured: 10 years
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Jun 2016 (estimated)
- Study startJul 2013
- Primary completionJul 2033 (estimated)
- Study completionJul 2033 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for HealthyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 5,000 participants (estimated)
Sponsor and investigators
- Lead sponsor
- National Heart Centre Singapore
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Stuart Cook, MBBS,PhD, Principal investigator, National Heart Centre Singapore
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT02804269
- Sponsor's protocol ID
- 2013/605/C
- Acronym
- Biobank
- Status last verified
- Jul 2013
- First submitted
- 31 May 2016
- Last updated
- 17 Jun 2016
- Results posted
- No
- Data monitoring committee
- No
- Individual data sharing
- No