Parkinson'sNCT02271685
Sound Estimation and Accuracy Task
A study testing Instructions about Overestimates, Instructions about Parkinson's and Instructions about Underestimates in people with Parkinson's and Alzheimer Disease, run by Carnegie Mellon University at 1 site in United States.
Trial summary
Participants will be assigned to complete computerized estimation tasks for which there is a component of accuracy, such as estimating the duration of sounds. Participants will be told that the task is used as an early diagnostic tool to detect those at risk for a medical condition (e.g., Parkinson's disease… Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Parkinson's, Alzheimer Disease
- What is being tested?
- Instructions about Overestimates, Instructions about Parkinson's and Instructions about Underestimates
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 600 participants
- Where
- 1 siteUnited States
- Study dates
- Feb 2015to May 2015
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- 18 or older
- Able to access tasks on computer
- Able to hear sounds played on computer
Who cannot join
- Computer speakers absent or not functioning
Trial locations and contacts
1 site in 1 country.
United States1 site
Carnegie Mellon University
Pittsburgh, Pennsylvania, 15213
About this study
Official title: Estimation and Accuracy in Sound Task Perceived to be Medically Diagnostic
Participants will be assigned to complete computerized estimation tasks for which there is a component of accuracy, such as estimating the duration of sounds. Participants will be told that the task is used as an early diagnostic tool to detect those at risk for a medical condition (e.g., Parkinson's disease, Alzheimer's disease). Instructions will be given to participants telling them that accuracy on the task is associated with the disease, whereas those who are not at risk of the disease tend to either overestimate or underestimate the duration of the sounds. The investigators examine whether such instructions about the purpose and diagnosticity of the tasks biases participants' responses to the tasks, leading them to purposefully be more inaccurate in their estimates.
Read the detailed description
Participants will be assigned to complete computerized tasks for which there is a component of accuracy, such as estimating the length, in time, of sounds. Participants will be told that the task is used as an early diagnostic tool to detect those at risk for a medical condition (e.g., Parkinson's disease, Alzheimer's disease). Instructions will be given to participants telling them that accuracy on the task is associated with the disease in question, whereas those who are not at risk of the disease tend to either overestimate or underestimate the duration of the sounds. The investigators examine whether such instructions about the purpose and diagnosticity of the tasks biases participants' responses to the tasks. The investigators collect additional survey measures as statistical controls and potential explanatory variables for variation in the performance on the tasks, and also test whether financial incentives for accuracy on these tasks improve the accuracy of responses to these tasks.
Following the task, all participants will be told that the tasks used are actually NOT diagnostic of the diseases in question, and that deception was used to learn how people respond to instructions about how a task can be used for diagnostic purposes.
- Conditions
- Parkinson's, Alzheimer Disease
- Being tested
- Instructions about Overestimates, Instructions about Parkinson's, Instructions about Underestimates, Instructions about Alzheimers
- Keywords
- Diagnostic Information, Risk Perception
- Medical subject headings
- Parkinson Disease, Alzheimer Disease
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Instructions about OverestimatesOther
Participants are told that overestimating the duration of sounds are associated with low disease risk.
Instructions about Parkinson'sOther
Participants are told that the task is about risk of Parkinson's disease.
Instructions about UnderestimatesOther
Participants are told that underestimating the duration of sounds are associated with low disease risk.
Instructions about AlzheimersOther
Participants are told that the task is about risk of Alzheimers disease.
| Study group | Role | What they receive |
|---|---|---|
| Overestimate Parkinson's | Experimental | People are told that overestimates on the sound estimation task are associated with being healthy and having a low risk of Parkinson's disease, whereas those who are accurate are more likely to develop the disease later in life. Receives: Other: Instructions about Overestimates; Other: Instructions about Parkinson's |
| Overestimate Alzheimers | Experimental | People are told that overestimates on the sound estimation task are associated with being healthy and having a low risk of Alzheimers disease, whereas those who are accurate are more likely to develop the disease later in life. Receives: Other: Instructions about Overestimates; Other: Instructions about Alzheimers |
| Underestimate Parkinson's | Experimental | People are told that underestimates on the sound estimation task are associated with being healthy and having a low risk of Parkinson's disease, whereas those who are accurate are more likely to develop the disease later in life. Receives: Other: Instructions about Parkinson's; Other: Instructions about Underestimates |
| Underestimate Alzheimers | Experimental | People are told that underestimates on the sound estimation task are associated with being healthy and having a low risk of Alzheimers disease, whereas those who are accurate are more likely to develop the disease later in life. Receives: Other: Instructions about Underestimates; Other: Instructions about Alzheimers |
What is being measured
The primary outcome is the main question the study is designed to answer.
Time Estimate
The estimate of the length of time elapsed during the sound file
Measured: 30 minutes
Secondary outcomes (2)
Time Generation
The length of time selected for the sound file to run by participants in a secondary task
Measured: 30 minutes
Perceived Risk of Disease
Scale question asking participants their perceived risk of having the diseases in the study
Measured: 30 minutes
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Oct 2014 (estimated)
- Study startFeb 2015
- Primary completionMay 2015
- Study completionMay 2015
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Parkinson'sStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Screening
- Allocation
- Randomised
- Intervention model
- Factorial
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 600 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Carnegie Mellon University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Eric VanEpps, Carnegie Mellon University
- Investigators
- Eric M VanEpps, MS, Principal investigator, Carnegie Mellon University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT02271685
- Sponsor's protocol ID
- HS14-553
- Status last verified
- May 2015
- First submitted
- 20 Oct 2014
- Last updated
- 21 May 2015
- Results posted
- No
- Data monitoring committee
- No
Study at a glance
From the registry record, last updated by the sponsor on 21 May 2015. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Estimation and Accuracy in Sound Task Perceived to be Medically Diagnostic
- ClinicalTrials.gov ID
- NCT02271685
- Acronym / sponsor ID
- HS14-553
- Conditions
- Parkinson's, Alzheimer Disease
- Keywords
- Diagnostic Information, Risk Perception
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 600 participants (estimated)
- Lead sponsor
- Carnegie Mellon UniversityUniversity, hospital or other
- Study start
- Feb 2015
- Primary completion
- May 2015 (actual)
- Study completion
- May 2015 (actual)
- First posted
- 22 Oct 2014 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Participants will be assigned to complete computerized estimation tasks for which there is a component of accuracy, such as estimating the duration of sounds. Participants will be told that the task is used as an early diagnostic tool to detect those at risk for a medical condition (e.g., Parkinson's disease, Alzheimer's disease). Instructions will be given to participants telling them that accuracy on the task is associated with the disease, whereas those who are not at risk of the disease tend to either overestimate or underestimate the duration of the sounds. The investigators examine whether such instructions about the purpose and diagnosticity of the tasks biases participants' responses to the tasks, leading them to purposefully be more inaccurate in their estimates.
Detailed description
Participants will be assigned to complete computerized tasks for which there is a component of accuracy, such as estimating the length, in time, of sounds. Participants will be told that the task is used as an early diagnostic tool to detect those at risk for a medical condition (e.g., Parkinson's disease, Alzheimer's disease). Instructions will be given to participants telling them that accuracy on the task is associated with the disease in question, whereas those who are not at risk of the disease tend to either overestimate or underestimate the duration of the sounds. The investigators examine whether such instructions about the purpose and diagnosticity of the tasks biases participants' responses to the tasks. The investigators collect additional survey measures as statistical controls and potential explanatory variables for variation in the performance on the tasks, and also test whether financial incentives for accuracy on these tasks improve the accuracy of responses to these tasks.
Following the task, all participants will be told that the tasks used are actually NOT diagnostic of the diseases in question, and that deception was used to learn how people respond to instructions about how a task can be used for diagnostic purposes.
Study design
- Primary purpose
- Screening
- Allocation
- Randomised
- Intervention model
- Factorial
- Masking
- Single blind (participant)
- Number of arms
- 4
| Arm | Type | Receives |
|---|---|---|
| Overestimate Parkinson's | Experimental | Other: Instructions about Overestimates, Other: Instructions about Parkinson'sPeople are told that overestimates on the sound estimation task are associated with being healthy and having a low risk of Parkinson's disease, whereas those who are accurate are more likely to develop the disease later in life. |
| Overestimate Alzheimers | Experimental | Other: Instructions about Overestimates, Other: Instructions about AlzheimersPeople are told that overestimates on the sound estimation task are associated with being healthy and having a low risk of Alzheimers disease, whereas those who are accurate are more likely to develop the disease later in life. |
| Underestimate Parkinson's | Experimental | Other: Instructions about Parkinson's, Other: Instructions about UnderestimatesPeople are told that underestimates on the sound estimation task are associated with being healthy and having a low risk of Parkinson's disease, whereas those who are accurate are more likely to develop the disease later in life. |
| Underestimate Alzheimers | Experimental | Other: Instructions about Underestimates, Other: Instructions about AlzheimersPeople are told that underestimates on the sound estimation task are associated with being healthy and having a low risk of Alzheimers disease, whereas those who are accurate are more likely to develop the disease later in life. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- 18 or older
- Able to access tasks on computer
- Able to hear sounds played on computer
Key exclusion criteria (1 listed)
- Computer speakers absent or not functioning
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Instructions about OverestimatesParticipants are told that overestimating the duration of sounds are associated with low disease risk. | Other | Overestimate Alzheimers, Overestimate Parkinson's |
| Instructions about Parkinson'sParticipants are told that the task is about risk of Parkinson's disease. | Other | Overestimate Parkinson's, Underestimate Parkinson's |
| Instructions about UnderestimatesParticipants are told that underestimating the duration of sounds are associated with low disease risk. | Other | Underestimate Alzheimers, Underestimate Parkinson's |
| Instructions about AlzheimersParticipants are told that the task is about risk of Alzheimers disease. | Other | Overestimate Alzheimers, Underestimate Alzheimers |
Primary outcome
Time Estimate
Time frame: 30 minutes
The estimate of the length of time elapsed during the sound file
2 secondary outcomes
Time Generation
Time frame: 30 minutes
Perceived Risk of Disease
Time frame: 30 minutes
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 21 May 2015.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Eric M VanEpps, MS principal investigator
Carnegie Mellon University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Instructions about Overestimates, Instructions about Parkinson's and Instructions about Underestimates in people with Parkinson's and Alzheimer Disease, run by Carnegie Mellon University at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 21 May 2015. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Time Estimate (time frame: 30 minutes). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 21 May 2015.