Motor PerformanceKFSP-REWARDNCT02189564
Rewarding Feedback in Motor Learning and Rehabilitation
A study testing Feedback about good performance, Feedback about good performance + money and Feedback about average performance in people with Motor Performance and Motor Learning, run by Kai Lutz, PhD at 1 site in Switzerland.
Trial summary
The effect of rewarding vs. non-rewarding feedback on acquisition of a motor skill is investigated in a single blinded parallel group design. Reward consists of performance dependent monetary reward, or of knowledge of performance in selected (above average) trials. Read more about this study
- Who is it for?
- Ages 20 to 35 yearsHealthy volunteers can take part
- Conditions the study is for
- Motor Performance, Motor Learning
- What is being tested?
- Feedback about good performance, Feedback about good performance + money and Feedback about average performance
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 45 participants
- Where
- 1 siteSwitzerland
- Study dates
- Jan 2014to Apr 2016
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 35 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- neurologically healthy
- right handed
Who cannot join
- Contraindications against magnetic resonance imaging
- pregnancy
Trial locations and contacts
1 site in 1 country.
Switzerland1 site
Cereneo, Center For Rehabilitation and Neurology
Vitznau, Canton of Lucerne, 6354
About this study
Official title: Die Auswirkung Von Dopaminergen Belohnungsreizen Auf Das Lernen Einer Motorischen Fertikgeit Bei Gesunden Probanden "Effects of Dopaminergic Reward on Motor Skill Learning in Healthy Subjects"
The effect of rewarding vs. non-rewarding feedback on acquisition of a motor skill is investigated in a single blinded parallel group design. Reward consists of performance dependent monetary reward, or of knowledge of performance in selected (above average) trials.
The investigators hypothesize improved motor skill learning and higher involvement of the dopaminsrgic system under rewarding vs. non-rewarding conditions.
- Conditions
- Motor Performance, Motor Learning
- Being tested
- Feedback about good performance, Feedback about good performance + money, Feedback about average performance
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Feedback about good performanceBehavioural
Feedback about good performance + moneyBehavioural
Feedback about average performanceBehavioural
| Study group | Role | What they receive |
|---|---|---|
| Intrinsic reward | Active comparator | Feedback about good performance Receives: Behavioral: Feedback about good performance |
| Intrinsic and extrinsic reward | Experimental | Feedback about good performance + money Receives: Behavioral: Feedback about good performance + money |
| Intrinsic reward (average performance) | Experimental | Feedback about random selection of trials Receives: Behavioral: Feedback about average performance |
What is being measured
The primary outcome is the main question the study is designed to answer.
Motor skill learning using an arc pointing task
temporal and spacial precision in an arc pointing task will be assessed using 5 different movement speeds during the above mentioned time periods before and after a specific motor learning programm. Learning will be assessed as change from pre-training to post training
Measured: about 10 minutes pre-training, about 10 min post training, about 24h post training
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Jul 2014 (estimated)
- Study startJan 2014
- Primary completionJul 2014
- Study completionApr 2016
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Motor PerformanceStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 45 participants (actual)
Sponsor and investigators
- Lead sponsor
- Kai Lutz, PhD
- Sponsor type
- Industry (pharma, biotech, devices)
- Collaborators
- University of Zurich
- Responsible party
- Sponsor-investigator, Kai Lutz, PhD, Cereneo AG
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT02189564
- Sponsor's protocol ID
- KFSP-SUB1-LU13054
- Acronym
- KFSP-REWARD
- Status last verified
- Apr 2016
- First submitted
- 30 Jun 2014
- Last updated
- 2 May 2016
- Results posted
- No
- Data monitoring committee
- No
Publications
Widmer M, Ziegler N, Held J, Luft A, Lutz K. Rewarding feedback promotes motor skill consolidation via striatal activity. Prog Brain Res. 2016;229:303-323. doi: 10.1016/bs.pbr.2016.05.006. Epub 2016 Jul 7.
PubMed 27926445
Study at a glance
From the registry record, last updated by the sponsor on 2 May 2016. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Die Auswirkung Von Dopaminergen Belohnungsreizen Auf Das Lernen Einer Motorischen Fertikgeit Bei Gesunden Probanden "Effects of Dopaminergic Reward on Motor Skill Learning in Healthy Subjects"
- ClinicalTrials.gov ID
- NCT02189564
- Acronym / sponsor ID
- KFSP-REWARD / KFSP-SUB1-LU13054
- Conditions
- Motor Performance, Motor Learning
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 45 participants (actual)
- Lead sponsor
- Kai Lutz, PhDIndustry (pharma, biotech, devices)
- Collaborators
- University of Zurich
- Study start
- Jan 2014
- Primary completion
- Jul 2014 (actual)
- Study completion
- Apr 2016 (actual)
- First posted
- 14 Jul 2014 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The effect of rewarding vs. non-rewarding feedback on acquisition of a motor skill is investigated in a single blinded parallel group design. Reward consists of performance dependent monetary reward, or of knowledge of performance in selected (above average) trials.
The investigators hypothesize improved motor skill learning and higher involvement of the dopaminsrgic system under rewarding vs. non-rewarding conditions.
Study design
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Intrinsic reward | Active comparator | Behavioral: Feedback about good performanceFeedback about good performance |
| Intrinsic and extrinsic reward | Experimental | Behavioral: Feedback about good performance + moneyFeedback about good performance + money |
| Intrinsic reward (average performance) | Experimental | Behavioral: Feedback about average performanceFeedback about random selection of trials |
Who may qualify
- Ages
- 20 to 35 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (2 listed)
- neurologically healthy
- right handed
Key exclusion criteria (2 listed)
- Contraindications against magnetic resonance imaging
- pregnancy
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Feedback about good performance | Behavioural | Intrinsic reward |
| Feedback about good performance + money | Behavioural | Intrinsic and extrinsic reward |
| Feedback about average performance | Behavioural | Intrinsic reward (average performance) |
Primary outcome
Motor skill learning using an arc pointing task
Time frame: about 10 minutes pre-training, about 10 min post training, about 24h post training
temporal and spacial precision in an arc pointing task will be assessed using 5 different movement speeds during the above mentioned time periods before and after a specific motor learning programm. Learning will be assessed as change from pre-training to post training
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 May 2016.
- Derived from this study: PubMed 27926445Widmer M, Ziegler N, Held J, Luft A, Lutz K. Rewarding feedback promotes motor skill consolidation via striatal activity. Prog Brain Res. 2016;229:303-323. doi: 10.1016/bs.pbr.2016.05.006. Epub 2016 Jul 7.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Feedback about good performance, Feedback about good performance + money and Feedback about average performance in people with Motor Performance and Motor Learning, run by Kai Lutz, PhD at 1 site in Switzerland.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 2 May 2016. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Switzerland. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Motor skill learning using an arc pointing task (time frame: about 10 minutes pre-training, about 10 min post training, about 24h post training). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT02189564, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 May 2016.