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OverweightInphactUmNCT01997970

NEAT - Prevention and Treatment of Overweight and Obesity.

A study testing Treadmill workstation and Health talk in people with Overweight and Obesity, run by Umeå University at 1 site in Sweden.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

This study will investigate the effect on Non-exercise Activity Thermogenesis (NEAT) when implementing active workstation at offices compared to conventional office work. The primary hypothesis is that this implementation will lead to a significant increase in time spent walking per day. Read more about this study

Who is it for?
Ages 40 to 67 yearsHealthy volunteers can take part
Conditions the study is for
Overweight, Obesity
What is being tested?
Treadmill workstation and Health talk
Could I receive a placebo?
No, everyone receives an active treatment
How many people
80 participants
Where
1 siteSweden
Study dates
Feb 2014to Dec 2015
Phase
Interventional
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 40 to 67 years
  • All sexes
  • Healthy volunteers accepted
  • Adult, Older adult

Who may be able to join

  • Office workers with mainly sedentary tasks
  • BMI 25-40

Who cannot join

  • Severe depression and/or anxiety
  • Exhaustion disorder
  • Diabetes Mellitus
  • Severe cardiovascular disease
  • Severe kidney disease
  • Musculoskeletal disorders that prohibit walking on a treadmill
Show all 13Show fewer
  • Contraindications for physical activity
  • Thyroidea illness
  • Pregnancy
  • For fMRI-study, additional exclusion criteria are:
  • Implanted metal- or electrical devices
  • Pregnancy
  • Extraneous metal pieces in the body

Trial locations and contacts

1 site in 1 country.

Sweden1 site

  • Umeå University

    Umeå

Other trials in Sweden

About this study

Official title: Non-exercise Activity Thermogenesis (NEAT) - Prevention and Treatment of Overweight and Obesity

This study will investigate the effect on Non-exercise Activity Thermogenesis (NEAT) when implementing active workstation at offices compared to conventional office work. The primary hypothesis is that this implementation will lead to a significant increase in time spent walking per day.

Read the detailed description

NEAT consists of the energy expenditure of the physical activities that are non sporting-like and that we perform in our everyday life, such as walking, cleaning, shoveling snow etc. Which occupation we have play a big role in how much we are able to active our NEAT during our days and those who have more active jobs can expend up to 1500kcal more per day than those with sedentary jobs.

This study aims to try and increase NEAT at offices where sedentary time often is high. Participants will be randomized to either an intervention group or to a control group. Participants in the control group will continue to work at their regular desk, but will receive an individual health talk in the beginning of the study where diet and physical activity recommendations will be discussed.Participants in the intervention group will receive the same individual health talk and a treadmill desk, which they will use for 12 months at self-selected speed. They will be recommended to walk on the treadmill for at least 1 hour per day.

Conditions
Overweight, Obesity
Being tested
Treadmill workstation, Health talk
Keywords
NEAT, Treadmill desk
Medical subject headings
Overweight, Obesity

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Treadmill workstationBehavioural

    The intervention group will receive a treadmill workstation for 12 months. They will use this at self-selected speed and will be recommended to use this for at least 1 hour per day. Participants in the control group will continue with conventional office work at their regular desk. Participants in the intervention group will receive four boosting e-mails during the study period, in which they will be encouraged to use the treadmill.

  • Health talkBehavioural

    Participants in both groups will receive a health talk with recommendations about diet and physical activity habits.

Study groups in NCT01997970
Study groupRoleWhat they receive
Treadmill workstationExperimentalWill receive a health talk with recommendations about diet and physical activity habits and will also receive a treadmill workstation at regular office site for 12 months.
Receives: Behavioral: Treadmill workstation; Behavioral: Health talk
Control groupExperimentalWill receive a health talk with recommendations about diet and physical activity habits. Will continue to work with conventional office work at their regular desk.
Receives: Behavioral: Health talk

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Change from baseline in physical activity and sedentariness at 12 months

    Measured with an accelerometer (ActiGraph) and an inclinometer (ActivPAL).

    Measured: Baseline, 12 months

Secondary outcomes (9)

  1. Change from baseline in metabolism at 12 months

    Metabolism: 2h glucose tolerance test. lipids, Hb1Ac

    Measured: Baseline, 12 months

  2. Change from baseline in anthropometrics at 12 months

    Length, height, weight, waist circumference, hip circumference, sagittal height, pulse, blood pressure.

    Measured: Baseline, 12 months

  3. Change from baseline in body composition at 12 months

    Measured with Dual X-Ray Absorptiometry (DXA)

    Measured: Baseline, 12 months

  4. Change from baseline in musculoskeletal pain at 12 months

    Measured with the Chronic Pain Grade Questionnaire

    Measured: Baseline, 12 months

  5. Change from baseline in stress at 12 months

    Measured by assessing cortisol levels in the saliva at 4 time points during one day. Also measured with the stress- and energy scale.

    Measured: Baseline, 12 months

  6. Change from baseline in depression/anxiety at 12 months

    Measured with the Hospital Anxiety and Depression Scale.

    Measured: Baseline, 12 months

  7. Change from baseline in Quality of Life at 12 months

    Measured with 2 questions from the SF-36.

    Measured: Baseline, 12 months

  8. Change from baseline in cognitive Function and functional brain response at 12 months

    Measured with a cognitive test battery and functional MRI (fMRI). Levels of Brain-Derived Neurotrophic Factor (BDNF) is measured in the plasma.

    Measured: Baseline, 12 months

  9. Qualitative interview study

    Participants will be interviewed about experiences from being part of the study and about attitudes and factors that influences them to be physically active.

    Measured: 12 months

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted28 Nov 2013 (estimated)
  2. Study startFeb 2014
  3. Primary completionDec 2015
  4. Study completionDec 2015

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Treatment
Allocation
Randomised
Intervention model
Parallel groups
Masking
Single blind
Who is masked
Outcomes assessor
Enrolment
80 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT01997970
Sponsor's protocol ID
2013-338-31
Acronym
InphactUm
Status last verified
May 2016
First submitted
2 Nov 2013
Last updated
12 May 2016
Results posted
No
Data monitoring committee
No

Publications

  • Bergman F, Matsson-Frost T, Jonasson L, Chorell E, Sorlin A, Wennberg P, Ohberg F, Ryberg M, Levine JA, Olsson T, Boraxbekk CJ. Walking Time Is Associated With Hippocampal Volume in Overweight and Obese Office Workers. Front Hum Neurosci. 2020 Aug 20;14:307. doi: 10.3389/fnhum.2020.00307. eCollection 2020.

    PubMed 32973475

  • Bergman F, Wahlstrom V, Stomby A, Otten J, Lanthen E, Renklint R, Waling M, Sorlin A, Boraxbekk CJ, Wennberg P, Ohberg F, Levine JA, Olsson T. Treadmill workstations in office workers who are overweight or obese: a randomised controlled trial. Lancet Public Health. 2018 Nov;3(11):e523-e535. doi: 10.1016/S2468-2667(18)30163-4. Epub 2018 Oct 12.

    PubMed 30322782

  • Bergman F, Boraxbekk CJ, Wennberg P, Sorlin A, Olsson T. Increasing physical activity in office workers--the Inphact Treadmill study; a study protocol for a 13-month randomized controlled trial of treadmill workstations. BMC Public Health. 2015 Jul 10;15:632. doi: 10.1186/s12889-015-2017-6.

    PubMed 26160221

Questions about this trial

What is this clinical trial studying?

A study testing Treadmill workstation and Health talk in people with Overweight and Obesity, run by Umeå University at 1 site in Sweden.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 2 inclusion and 13 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 12 May 2016. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Sweden. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Change from baseline in physical activity and sedentariness at 12 months (time frame: Baseline, 12 months). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT01997970, which also lists 3 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 12 May 2016; AzTrials last refreshed its copy on 8 Nov 2026.

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