Repeated Implantation FailureNCT01933893
Follicular Versus Luteal Pipelle in Repeated Implantation Failure Patients
An observational study of Repeated Implantation Failure, run by Assaf-Harofeh Medical Center.
Trial summary
Pipelle was found to increase pregnancy and implantation rates in women undergoing IVF treatment in general, and in particular in repeated implantation failure (RIF). However, there is virtually no data regarding the optimal timing for the pipelle. Read more about this study
- Who is it for?
- Ages 18 to 40 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Repeated Implantation Failure
- How many people
- 100 participants
- Where
- No sites listed yet
- Study dates
- Oct 2013to May 2014
- How long will I take part?
- 1 Year
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 40 years
- Women only
- Healthy volunteers accepted
- Adult
Study population: Women diagnosed with repeated implantation failure (RIF) who are undergoing IVF treatment.
Who may be able to join
- Women diagnosed with RIF who are going to start a new IVF treatment
Who cannot join
- Known hydrosalpinx body mass index (BMI) >29 kg/m2 or <18 kg/m2 Low ovarian response
About this study
Pipelle was found to increase pregnancy and implantation rates in women undergoing IVF treatment in general, and in particular in repeated implantation failure (RIF). However, there is virtually no data regarding the optimal timing for the pipelle.
The current study aims to compare between follicular and luteal pipelle on pregnancy rate in RIF patients.
- Conditions
- Repeated Implantation Failure
- Keywords
- Pipelle, luteal, follicular, implantation
What is being measured
The primary outcome is the main question the study is designed to answer.
Pregnancy rate
Measured: April, 2014
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted2 Sep 2013 (estimated)
- Study startOct 2013
- Primary completionMay 2014 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Repeated Implantation FailureStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Prospective
- Enrolment
- 100 participants (estimated)
- Target duration
- 1 Year
Sponsor and investigators
- Lead sponsor
- Assaf-Harofeh Medical Center
- Sponsor type
- Other government
- Responsible party
- Sponsor
- Investigators
- Ido Ben-Ami, MD, PhD, Principal investigator, Assaf Harofeh Medical Center, Zerifin, Israel
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT01933893
- Sponsor's protocol ID
- 139/13
- Status last verified
- Aug 2013
- First submitted
- 29 Aug 2013
- Last updated
- 2 Sep 2013
- Results posted
- No
- Data monitoring committee
- No
Study at a glance
From the registry record, last updated by the sponsor on 2 Sep 2013. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Follicular Versus Luteal Pipelle in Repeated Implantation Failure Patients
- ClinicalTrials.gov ID
- NCT01933893
- Acronym / sponsor ID
- 139/13
- Conditions
- Repeated Implantation Failure
- Keywords
- Pipelle, luteal, follicular, implantation
- Study type
- Observational
- Recruitment status
- Unknown status
- Enrolment
- 100 participants (estimated)
- Lead sponsor
- Assaf-Harofeh Medical CenterOther government
- Study start
- Oct 2013
- Primary completion
- May 2014 (estimated)
- First posted
- 2 Sep 2013 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Pipelle was found to increase pregnancy and implantation rates in women undergoing IVF treatment in general, and in particular in repeated implantation failure (RIF). However, there is virtually no data regarding the optimal timing for the pipelle.
The current study aims to compare between follicular and luteal pipelle on pregnancy rate in RIF patients.
Study design
- Observational model
- Case-control
- Time perspective
- Prospective
- Target follow-up
- 1 Year
Who may qualify
- Ages
- 18 to 40 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult
- Study population
- Women diagnosed with repeated implantation failure (RIF) who are undergoing IVF treatment.
Key inclusion criteria (1 listed)
- Women diagnosed with RIF who are going to start a new IVF treatment
Key exclusion criteria (1 listed)
- Known hydrosalpinx body mass index (BMI) >29 kg/m2 or <18 kg/m2 Low ovarian response
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Pregnancy rate
Time frame: April, 2014
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Sep 2013.
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Effect of Acupuncture on IVF Pregnancy Outcomes for Women With RIF
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Application of Platelet-rich Plasma (PRP) in Reproductive Medicine
Premature Ovarian Insufficiency, Intrauterine Adhesion
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Ido Ben-Ami, MD, PhD principal investigator
Assaf Harofeh Medical Center, Zerifin, Israel
Questions about this trial
What is this clinical trial studying?
An observational study of Repeated Implantation Failure, run by Assaf-Harofeh Medical Center.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 2 Sep 2013. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pregnancy rate (time frame: April, 2014). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Sep 2013; AzTrials last refreshed its copy on 8 Nov 2026.