Allergy to Grass PollenNCT01686022
Grass Sensitisation and Allergic Rhinitis in Thai Patients
An observational study of Allergy to Grass Pollen and Allergic Rhinitis Due to Weed Pollens, run by Mahidol University at 1 site in Thailand.
Trial summary
Allergic rhinitis patients are the patients who have nasal symptoms when triggered by indoor or outdoor allergens. Outdoor allergen can be divided into grass, tree, or weed. The type of grass or weed are different in various part of the world. The allergens from grass and weed has never been studied in Thailand. Read more about this study
- Who is it for?
- Ages 10 to 50 yearsHealthy volunteers can take part
- Conditions the study is for
- Allergy to Grass Pollen, Allergic Rhinitis Due to Weed Pollens
- What is being tested?
- Immunoblot
- How many people
- 40 participants
- Where
- 1 siteThailand
- Study dates
- Oct 2012to Oct 2015
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 10 to 50 years
- All sexes
- Healthy volunteers accepted
- Child, Adult
Study population: Allergy Clinic
Who may be able to join
- Allergic rhinitis patients age 10-50 years old
- Control: healthy volunteer age 18-50 years old
Who cannot join
- Chronic illness such as cardiovascular diseases, liver diseases
- History of anaphylaxis
- Pregnancy
Trial locations and contacts
1 site in 1 country.
About this study
Official title: The Study of Allergens From Grass and Weed Which Are Causes of Allergic Rhinitis in Thai Patients
Allergic rhinitis patients are the patients who have nasal symptoms when triggered by indoor or outdoor allergens. Outdoor allergen can be divided into grass, tree, or weed. The type of grass or weed are different in various part of the world. The allergens from grass and weed has never been studied in Thailand. This study will find the major allergen from Bermuda grass, Johnson grass, Para grass, sedge, and ragweed, which are very common in Thailand. In addition, the investigators will study about the cross-reactivity among these group of allergen.
Read the detailed description
To find the major allergen of grass and weed, the serum of patients will be used to bind with the allergen extract by immunoblot study.
The ELISA-inhibition will be used to study about cross-reactivity among various kinds of grass and weed.
- Being tested
- Immunoblot
- Keywords
- Grass, Major allergen, cross-reactivity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
ImmunoblotOther
serum specific IgE binds to grass extract by immunoblot
| Study group | Role | What they receive |
|---|---|---|
| Pollen Allergy | Pollen allergy and control will have the same intervention, ie. Skin prick test and collect serum samples.Then measure the specificIgE, immunoblot, and ELISA inhibition Receives: Other: Immunoblot |
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Sep 2012 (estimated)
- Study startOct 2012
- Primary completionOct 2015
- Study completionOct 2015
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Allergy to Grass PollenStudies of the same condition, open and under way.
- More trials run by Mahidol UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Enrolment
- 40 participants (actual)
Sponsor and investigators
- Lead sponsor
- Mahidol University
- Sponsor type
- University, hospital or other
- Collaborators
- National Research Council of Thailand
- Responsible party
- Principal investigator, Punchama Pacharn, Mahidol University
- Investigators
- Punchama Pacharn, MD, Principal investigator, Mahidol University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT01686022
- Sponsor's protocol ID
- NRCT_G04
- Status last verified
- Sep 2016
- First submitted
- 12 Sep 2012
- Last updated
- 14 Sep 2016
- Results posted
- No
- Data monitoring committee
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 14 Sep 2016. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Study of Allergens From Grass and Weed Which Are Causes of Allergic Rhinitis in Thai Patients
- ClinicalTrials.gov ID
- NCT01686022
- Acronym / sponsor ID
- NRCT_G04
- Keywords
- Grass, Major allergen, cross-reactivity
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 40 participants (actual)
- Lead sponsor
- Mahidol UniversityUniversity, hospital or other
- Collaborators
- National Research Council of Thailand
- Study start
- Oct 2012
- Primary completion
- Oct 2015 (actual)
- Study completion
- Oct 2015 (actual)
- First posted
- 17 Sep 2012 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Allergic rhinitis patients are the patients who have nasal symptoms when triggered by indoor or outdoor allergens. Outdoor allergen can be divided into grass, tree, or weed. The type of grass or weed are different in various part of the world. The allergens from grass and weed has never been studied in Thailand. This study will find the major allergen from Bermuda grass, Johnson grass, Para grass, sedge, and ragweed, which are very common in Thailand. In addition, the investigators will study about the cross-reactivity among these group of allergen.
Detailed description
To find the major allergen of grass and weed, the serum of patients will be used to bind with the allergen extract by immunoblot study.
The ELISA-inhibition will be used to study about cross-reactivity among various kinds of grass and weed.
Study design
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Pollen Allergy | – | Other: ImmunoblotPollen allergy and control will have the same intervention, ie. Skin prick test and collect serum samples.Then measure the specificIgE, immunoblot, and ELISA inhibition |
Who may qualify
- Ages
- 10 to 50 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult
- Study population
- Allergy Clinic
Key inclusion criteria (2 listed)
- Allergic rhinitis patients age 10-50 years old
- Control: healthy volunteer age 18-50 years old
Key exclusion criteria (3 listed)
- Chronic illness such as cardiovascular diseases, liver diseases
- History of anaphylaxis
- Pregnancy
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Immunoblotserum specific IgE binds to grass extract by immunoblot | Other | Pollen Allergy |
Primary outcome
Not reported in the source record.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 Sep 2016.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Punchama Pacharn, MD principal investigator
Mahidol University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Allergy to Grass Pollen and Allergic Rhinitis Due to Weed Pollens, run by Mahidol University at 1 site in Thailand.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 14 Sep 2016. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Thailand. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Sep 2016.