Myocardial InfarctionNCT01182064
Acute Myocardial Infarction by Penetrating Cardiac Trauma
An observational study of Myocardial Infarction, run by Universidad de Antioquia at 1 site in Colombia.
Trial summary
Patients with a cardiac stab wound could be complicated by a posttraumatic acute myocardial infarction (PAMI). Traditionally, the investigators can explain it by the occlusion of a coronary artery; but the PAMI isn´t constantly related with coronary artery injuries or their damage in the cardiac injury repair. Read more about this study
- Who is it for?
- Ages 14 to 80 years
- Conditions the study is for
- Myocardial Infarction
- How many people
- 51 participants
- Where
- 1 siteColombia
- Study dates
- Apr 2007to Apr 2008
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 14 to 80 years
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Study population: The study included patients admitted to the emergency department of the San Vicente de Paul University Hospital with a penetrating stab cardiac injury without previous injuries
Who may be able to join
- Heart stab Injury
Who cannot join
- Previous cardiac injuries, coronary artery disease with previous diagnostic, previous coronary angiography (for any indication)
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Relationship of Echocardiographic and Coronary Angiographic Findings in Patients With Acute Myocardial Infarction Secondary to Penetrating Cardiac Trauma
Patients with a cardiac stab wound could be complicated by a posttraumatic acute myocardial infarction (PAMI). Traditionally, the investigators can explain it by the occlusion of a coronary artery; but the PAMI isn´t constantly related with coronary artery injuries or their damage in the cardiac injury repair. The investigators objectives are to know the PAMI incidence, make an approximation to PAMI pathophysiology, and propose management strategies.
- Conditions
- Myocardial Infarction
- Keywords
- Heart injuries, Posttraumatic myocardial infarction, Echocardiography, Coronary angiography
- Medical subject headings
- Myocardial Infarction, Heart Injuries
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Non infarct | Not described | |
| Posttraumatic acute myocardial infarct without coronary injury | Not described | |
| Posttraumatic acute myocardial infarct with coronary injury | Not described |
What is being measured
The primary outcome is the main question the study is designed to answer.
Posttraumatic acute myocardial infarct
Measured: 2 days
Secondary outcomes (1)
Posttraumatic acute myocardial infarct without coronary injury
Measured: 10 days
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 Aug 2010 (estimated)
- Study startApr 2007
- Study completionApr 2008
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Myocardial InfarctionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Prospective
- Enrolment
- 51 participants (actual)
Sponsor and investigators
- Lead sponsor
- Universidad de Antioquia
- Sponsor type
- University, hospital or other
- Investigators
- Carlos H Morales, MD, MSc, Study director, Antioquia University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT01182064
- Sponsor's protocol ID
- WCJWJ1
- Status last verified
- Mar 2007
- First submitted
- 13 Aug 2010
- Last updated
- 16 Aug 2010
- Results posted
- No
- Data monitoring committee
- No
Publications
Castano W, Morales CH, Senior JM, Benjumea WY, Sanchez J. Relationship of echocardiographic and coronary angiographic findings in patients with acute myocardial infarction secondary to penetrating cardiac trauma. J Trauma Acute Care Surg. 2012 Jul;73(1):111-6. doi: 10.1097/TA.0b013e318256a0d8.
PubMed 22743380
Study at a glance
From the registry record, last updated by the sponsor on 16 Aug 2010. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Relationship of Echocardiographic and Coronary Angiographic Findings in Patients With Acute Myocardial Infarction Secondary to Penetrating Cardiac Trauma
- ClinicalTrials.gov ID
- NCT01182064
- Acronym / sponsor ID
- WCJWJ1
- Conditions
- Myocardial Infarction
- Keywords
- Heart injuries, Posttraumatic myocardial infarction, Echocardiography, Coronary angiography
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 51 participants (actual)
- Lead sponsor
- Universidad de AntioquiaUniversity, hospital or other
- Study start
- Apr 2007
- Study completion
- Apr 2008 (actual)
- First posted
- 16 Aug 2010 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Patients with a cardiac stab wound could be complicated by a posttraumatic acute myocardial infarction (PAMI). Traditionally, the investigators can explain it by the occlusion of a coronary artery; but the PAMI isn´t constantly related with coronary artery injuries or their damage in the cardiac injury repair. The investigators objectives are to know the PAMI incidence, make an approximation to PAMI pathophysiology, and propose management strategies.
Study design
- Observational model
- Case-control
- Time perspective
- Prospective
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Non infarct | – | – |
| Posttraumatic acute myocardial infarct without coronary injury | – | – |
| Posttraumatic acute myocardial infarct with coronary injury | – | – |
Who may qualify
- Ages
- 14 to 80 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
- Study population
- The study included patients admitted to the emergency department of the San Vicente de Paul University Hospital with a penetrating stab cardiac injury without previous injuries
Key inclusion criteria (1 listed)
- Heart stab Injury
Key exclusion criteria (1 listed)
- Previous cardiac injuries, coronary artery disease with previous diagnostic, previous coronary angiography (for any indication)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Posttraumatic acute myocardial infarct
Time frame: 2 days
1 secondary outcome
Posttraumatic acute myocardial infarct without coronary injury
Time frame: 10 days
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 16 Aug 2010.
- Derived from this study: PubMed 22743380Castano W, Morales CH, Senior JM, Benjumea WY, Sanchez J. Relationship of echocardiographic and coronary angiographic findings in patients with acute myocardial infarction secondary to penetrating cardiac trauma. J Trauma Acute Care Surg. 2012 Jul;73(1):111-6. doi: 10.1097/TA.0b013e318256a0d8.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Carlos H Morales, MD, MSc study director
Antioquia University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Myocardial Infarction, run by Universidad de Antioquia at 1 site in Colombia.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 16 Aug 2010. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Colombia. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Posttraumatic acute myocardial infarct (time frame: 2 days). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT01182064, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Aug 2010.