Memory LossNCT01123018
Screening for Memory Studies
An observational study of Memory Loss and Memory Deficits, run by John Wesson Ashford Jr at 1 site in United States.
Trial summary
We hope to recruit participants into various clinical trials and research projects. Read more about this study
- Who is it for?
- Ages 21 years and olderHealthy volunteers can take part
- Conditions the study is for
- Memory Loss, Memory Deficits, Dementia
- What is being tested?
- Memtrax Memory screening test
- Type of treatment
- Lifestyle or therapy programme
- How many people
- 1 participants
- Where
- 1 siteUnited States
- Study dates
- Jun 2007to Dec 2023
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 21 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: healthy older adults with memory concerns
Who may be able to join
- Age 21 or over.
Who cannot join
- Major psychiatric problems.
- Major medical problems.
- Aversion to test-taking.
Trial locations and contacts
1 site in 1 country.
United States1 site
VA Palo Alto Health Care System
Palo Alto, California, 94304
About this study
We hope to recruit participants into various clinical trials and research projects.
Read the detailed description
The purpose of this protocol is to advertise, recruit, and do a preliminary screen for various clinical trials. Anonymous information collected will be entered in a database available to researchers connected with the Stanford/VA Aging Clinical Research Center, located at VA Palo Alto Health Care System, Palo Alto Division.
- Conditions
- Memory Loss, Memory Deficits, Dementia, Alzheimer Disease
- Being tested
- Memtrax Memory screening test
- Keywords
- Memory Loss
- Medical subject headings
- Memory Disorders, Dementia, Alzheimer Disease
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Memtrax Memory screening testBehavioural
Also called Memory screening
Memory Screening test
| Study group | Role | What they receive |
|---|---|---|
| Older Adults | Persons over age 60 Participants will complete the Memtrax memory screening test Receives: Behavioral: Memtrax Memory screening test |
What is being measured
The primary outcome is the main question the study is designed to answer.
Memory Impairment
The primary outcome measure on a 50 item Continuous Recognition Task with 25 repeated items, first display of an item is 3 seconds, new image immediately after a response (MemTrax, see: reference), is number of HITs (a memory measure). Less than 20 suggests memory impairment and will trigger referral to a memory study.
Measured: 90 seconds to 150 seconds (normal less than 100 seconds)
Secondary outcomes (1)
Processing speed measurement with MemTrax
Secondary outcome measure is response time to HITs (a measure of memory processing speed), usually 0.550 to 1.5 seconds. Slower than 1.2 seconds suggests a memory, attention, or processing speed problem, will also trigger a referral to the memory study. Note, a third measure, number of Correct Rejections (a measure of executive function), is used to validate the first and second outcome measures. Values below 20 suggest that the other measures might not be valid.
Measured: 90 - 150 seconds (normal - 95 seconds)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 May 2010 (estimated)
- Study startJun 2007
- Primary completionDec 2023
- Study completionDec 2023
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for Memory LossStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Prospective
- Enrolment
- 1 participants (actual)
Sponsor and investigators
- Lead sponsor
- John Wesson Ashford Jr
- Sponsor type
- US federal agency
- Responsible party
- Sponsor-investigator, John Wesson Ashford Jr, VA Palo Alto Health Care System
- Investigators
- J. Wesson Ashford Jr., MD, PhD, Principal investigator, Stanford University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT01123018
- Sponsor's protocol ID
- SU-06302009-2900
- Status last verified
- Aug 2026
- First submitted
- 11 May 2010
- Last updated
- 26 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- Individual data sharing
- Undecided
Publications
Ashford JW, Borson S. Primary care screening for dementia and mild cognitive impairment. JAMA. 2008 Mar 12;299(10):1132-3; author reply 1133-4. doi: 10.1001/jama.299.10.1132-b. No abstract available.
PubMed 18334685Clifford JO Jr, Anand S, Tarpin-Bernard F, Bergeron MF, Ashford CB, Bayley PJ, Ashford JW. Episodic memory assessment: effects of sex and age on performance and response time during a continuous recognition task. Front Hum Neurosci. 2024 Apr 4;18:1304221. doi: 10.3389/fnhum.2024.1304221. eCollection 2024.
PubMed 38638807
Study at a glance
From the registry record, last updated by the sponsor on 26 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Screening for Memory Studies
- ClinicalTrials.gov ID
- NCT01123018
- Acronym / sponsor ID
- SU-06302009-2900
- Conditions
- Memory Loss, Memory Deficits, Dementia, Alzheimer Disease
- Keywords
- Memory Loss
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 1 participants (actual)
- Lead sponsor
- John Wesson Ashford JrUS federal agency
- Study start
- Jun 2007
- Primary completion
- Dec 2023 (actual)
- Study completion
- Dec 2023 (actual)
- First posted
- 13 May 2010 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
We hope to recruit participants into various clinical trials and research projects.
Detailed description
The purpose of this protocol is to advertise, recruit, and do a preliminary screen for various clinical trials. Anonymous information collected will be entered in a database available to researchers connected with the Stanford/VA Aging Clinical Research Center, located at VA Palo Alto Health Care System, Palo Alto Division.
Study design
- Observational model
- Other
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Older Adults | – | Behavioral: Memtrax Memory screening testPersons over age 60 Participants will complete the Memtrax memory screening test |
Who may qualify
- Ages
- 21 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- healthy older adults with memory concerns
Key inclusion criteria (1 listed)
- Age 21 or over.
Key exclusion criteria (3 listed)
- Major psychiatric problems.
- Major medical problems.
- Aversion to test-taking.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Memtrax Memory screening testAlso: Memory screeningMemory Screening test | Behavioural | Older Adults |
Primary outcome
Memory Impairment
Time frame: 90 seconds to 150 seconds (normal less than 100 seconds)
The primary outcome measure on a 50 item Continuous Recognition Task with 25 repeated items, first display of an item is 3 seconds, new image immediately after a response (MemTrax, see: reference), is number of HITs (a memory measure). Less than 20 suggests memory impairment and will trigger referral to a memory study.
1 secondary outcome
Processing speed measurement with MemTrax
Time frame: 90 - 150 seconds (normal - 95 seconds)
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 26 Aug 2026.
- Background: PubMed 18334685Ashford JW, Borson S. Primary care screening for dementia and mild cognitive impairment. JAMA. 2008 Mar 12;299(10):1132-3; author reply 1133-4. doi: 10.1001/jama.299.10.1132-b. No abstract available.
- Results publication: PubMed 38638807Clifford JO Jr, Anand S, Tarpin-Bernard F, Bergeron MF, Ashford CB, Bayley PJ, Ashford JW. Episodic memory assessment: effects of sex and age on performance and response time during a continuous recognition task. Front Hum Neurosci. 2024 Apr 4;18:1304221. doi: 10.3389/fnhum.2024.1304221. eCollection 2024.
- The computerized continuous recognition task used for this trial.Link provided by the sponsor.
- Individual participant dataSharing planned: Undecided
Related trials for Memory Loss
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NON-INVASIVE BRAIN STIMULATION FOR MEMORY LOSS IN EARLY ALZHEIMER'S DISEASE
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Cholinergic Enhancement of Theta
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
J. Wesson Ashford Jr., MD, PhD principal investigator
Stanford University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Memory Loss and Memory Deficits, run by John Wesson Ashford Jr at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 26 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Memory Impairment (time frame: 90 seconds to 150 seconds (normal less than 100 seconds)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT01123018, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 Aug 2026.