Coronary Heart DiseaseNCT00918242
Prevalence of Coronary Artery Disease in the Siblings of Premature Coronary Heart Disease
An observational study of Coronary Heart Disease, run by Yonsei University at 1 site in South Korea.
Trial summary
The aim of this prospective study is to investigate the prevalence of coronary artery disease using computed tomography with family history of premature coronary heart disease Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Coronary Heart Disease
- How many people
- 87 participants
- Where
- 1 siteSouth Korea
- Study dates
- Jun 2009to Sep 2012
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: the siblings of premature coronary heart disease (male<55years old, female<65yeasrs old: Framingham Heart Study) patients admitted relevant hospital within 1 year
Who may be able to join
- within 1 year
- the siblings of premature coronary heart disease (male<55years old, female<65yeasrs old: Framingham Heart Study) patients admitted relevant hospital
Who cannot join
- Documented coronary heart disease
- experienced adverse events with relevant treatment
- contraindicated with beta-blockers
- Any woman of childbearing potential who is pregnant, seeking to become pregnant or suspects
Trial locations and contacts
1 site in 1 country.
South Korea1 site, 1 recruiting
- Recruiting
Yonsei University Severance Hospital
Seoul, 102-752
Hyuk-Jae Chang, MD, 82-2-2228-8454, hjchang@yuhs.ac
About this study
Official title: Assessment of Occult CAD: Premature CAD Sibling Study (PreCASS)
The aim of this prospective study is to investigate the prevalence of coronary artery disease using computed tomography with family history of premature coronary heart disease
- Conditions
- Coronary Heart Disease
- Keywords
- Coronary Heart Disease, computed tomography, prevalence of coronary artery disease
- Medical subject headings
- Coronary Disease
What is being measured
The primary outcome is the main question the study is designed to answer.
evaluation of prevalence to coronary artery disease using CT
Measured: within 2 weeks from CT scanning
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 Jun 2009 (estimated)
- Study startJun 2009
- Primary completionSep 2012 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Coronary Heart DiseaseStudies of the same condition, open and under way.
- More trials run by Yonsei UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 87 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Yonsei University
- Sponsor type
- University, hospital or other
- Collaborators
- Korean Society of Lipidology and Atherosclerosis
- Responsible party
- Principal investigator, Hyuk-Jae Chang, Yonsei University
- Investigators
- Hyuk-Jae Chang, MD, PhD, Principal investigator, Cardiology Division, Severance Cardiovascular Hospital, Yonsei University College of Medicine
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT00918242
- Sponsor's protocol ID
- 20090616
- Status last verified
- Jul 2012
- First submitted
- 10 Jun 2009
- Last updated
- 23 Jul 2012
- Results posted
- No
- Data monitoring committee
- Yes
Publications
Arad Y, Spadaro LA, Goodman K, Newstein D, Guerci AD. Prediction of coronary events with electron beam computed tomography. J Am Coll Cardiol. 2000 Oct;36(4):1253-60. doi: 10.1016/s0735-1097(00)00872-x.
PubMed 11028480
Study at a glance
From the registry record, last updated by the sponsor on 23 Jul 2012. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Assessment of Occult CAD: Premature CAD Sibling Study (PreCASS)
- ClinicalTrials.gov ID
- NCT00918242
- Acronym / sponsor ID
- 20090616
- Conditions
- Coronary Heart Disease
- Keywords
- Coronary Heart Disease, computed tomography, prevalence of coronary artery disease
- Study type
- Observational
- Recruitment status
- Unknown status
- Enrolment
- 87 participants (estimated)
- Lead sponsor
- Yonsei UniversityUniversity, hospital or other
- Collaborators
- Korean Society of Lipidology and Atherosclerosis
- Study start
- Jun 2009
- Primary completion
- Sep 2012 (estimated)
- First posted
- 11 Jun 2009 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this prospective study is to investigate the prevalence of coronary artery disease using computed tomography with family history of premature coronary heart disease
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- the siblings of premature coronary heart disease (male<55years old, female<65yeasrs old: Framingham Heart Study) patients admitted relevant hospital within 1 year
Key inclusion criteria (2 listed)
- within 1 year
- the siblings of premature coronary heart disease (male<55years old, female<65yeasrs old: Framingham Heart Study) patients admitted relevant hospital
Key exclusion criteria (4 listed)
- Documented coronary heart disease
- experienced adverse events with relevant treatment
- contraindicated with beta-blockers
- Any woman of childbearing potential who is pregnant, seeking to become pregnant or suspects
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
evaluation of prevalence to coronary artery disease using CT
Time frame: within 2 weeks from CT scanning
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Jul 2012.
- Results publication: PubMed 11028480Arad Y, Spadaro LA, Goodman K, Newstein D, Guerci AD. Prediction of coronary events with electron beam computed tomography. J Am Coll Cardiol. 2000 Oct;36(4):1253-60. doi: 10.1016/s0735-1097(00)00872-x.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Hyuk-Jae Chang, MD, PhD principal investigator
Cardiology Division, Severance Cardiovascular Hospital, Yonsei University College of Medicine
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Coronary Heart Disease, run by Yonsei University at 1 site in South Korea.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 23 Jul 2012. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in South Korea. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
Contact Hyuk-Jae Chang, MD, PhD (82-2-2228-8461, hjchang@yuhs.ac), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
evaluation of prevalence to coronary artery disease using CT (time frame: within 2 weeks from CT scanning). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT00918242, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Jul 2012; AzTrials last refreshed its copy on 8 Nov 2026.