Chronic SinusitisNCT00880516
Genetic Factors in Chronic Sinusitis
An observational study of Chronic Sinusitis, run by University of Chicago at 1 site in United States.
Trial summary
The purpose of this study is to learn more about the genetics of chronic sinusitis and identify genes involved in chronic sinusitis. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Chronic Sinusitis
- How many people
- 1,200 participants
- Where
- 1 siteUnited States
- Study dates
- 1 Apr 2009to Dec 2027
- Phase
- Observational
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Adults with and without chronic sinusitis
Who may be able to join
- Age> 18 years
- Diagnosis of chronic sinusitis or normal sinuses (with verification by imaging.) You must have a recent CT scan showing either normal sinuses or the presence of sinus disease.
Who cannot join
- Genetic or acquired immunodeficiency
- Ciliary dyskinesia
- Cystic fibrosis
- Autoimmune disease
- Cancer of the sinuses
Trial locations and contacts
1 site in 1 country.
About this study
The purpose of this study is to learn more about the genetics of chronic sinusitis and identify genes involved in chronic sinusitis.
- Conditions
- Chronic Sinusitis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| control | Adults with normal sinuses | |
| case | Adults with chronic sinusitis and positive findings on imaging. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Association of genetic variation with CRS disease status
Measured: Adult age
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Apr 2009 (estimated)
- Study start1 Apr 2009
- Primary completionDec 2027 (estimated)
- Study completionDec 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Chronic SinusitisStudies of the same condition, open and under way.
- More trials run by University of ChicagoThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Prospective
- Enrolment
- 1,200 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Chicago
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Jayant Pinto, MD, Principal investigator, University of Chicago
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT00880516
- Sponsor's protocol ID
- 16749A
- Status last verified
- Jan 2026
- First submitted
- 9 Apr 2009
- Last updated
- 2 Feb 2026
- Results posted
- No
- Data monitoring committee
- No