AzTrials
AzTrials

Non Small Cell Lung CarcinomaPhase 3NCT00080340

Study of TLK286 (Telcyta) vs. Gefitinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer

A Phase 3 study testing TLK286 (Telcyta) HCl for Injection and gefitinib (Iressa) in people with Non Small Cell Lung Carcinoma, run by Telik at 338 sites in 8 countries.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
Search all trials

Trial summary

The purpose of this study is to determine if TLK286(Telcyta) is more effective than gefitinib (Iressa) in the treatment of non-small cell lung cancer. Read more about this study

Who is it for?
Ages 18 years and older
Conditions the study is for
Non Small Cell Lung Carcinoma
What is being tested?
TLK286 (Telcyta) HCl for Injection and gefitinib (Iressa)
Type of treatment
Injection or infusion
How many people
520 participants
Where
338 sitesin 8 countries
Study dates
Start not givento May 2005
Phase
Phase 3
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 years and older
  • All sexes
  • No healthy volunteers
  • Adult, Older adult

Who may be able to join

  • Clinical diagnosis of non-small cell lung cancer
  • Non-small cell lung cancer that is not curable with surgery, radiation, or combined modality chemoradiation
  • Failed two prior chemotherapy regimens which must have included platinum
  • Measurable disease

Who cannot join

  • Treatment with more than two prior chemotherapy regimens
  • History of bone marrow transplantation or stem cell support
  • Pregnant or lactating women
  • Known history of prior gefitinib therapy
  • Known history of prior TLK286 therapy

Trial locations and contacts

338 sites in 8 countries.

338 sites in 8 countries

United States270 sites

  • New York Oncology Hematology, P. C.

    Albany, New York, 12208

  • New Mexico Oncology Hematology Consultants, Ltd.

    Albuquerque, New Mexico, 87109

  • Moroose, Reynolds, Castillo, Robinson & Lukeman, MD, PA

    Altamonte Springs, Florida, 32701

  • St. Joseph Mercy Hospital, Cancer Center, OC 139

    Ann Arbor, Michigan, 48106

  • Annapolis Oncology Center

    Annapolis, Maryland, 21401

  • East Bay Medical Oncology/Hematology Medical Associates, Inc.

    Antioch, California, 94509

  • Arlington Cancer Center

    Arlington, Texas, 76012

  • Business Park Drive

    Armonk, New York, 10504

  • Peachtree Hematology & Oncology Consultants, P. C.

    Atlanta, Georgia, 30309

  • Auerbach Hematology Oncology Associates

    Baltimore, Maryland, 21237

  • Franklin Square Hospital Center

    Baltimore, Maryland, 21237

  • North Shore Oncology Hematology Associates

    Barrington, Illinois, 60010

  • Little Rock Hematology Oncology Benton

    Benton, Arkansas, 72015

  • Highlands Oncology Group

    Bentonville, Arkansas, 72702

  • Center for Cancer and Blood Disorders

    Bethesda, Maryland, 20817

  • Vita Hematology Oncology, P.C.

    Bethlehem, Pennsylvania, 18015

  • Hematology Oncology Associates of the Quad Cities

    Bettendorf, Iowa, 52722

  • UAB CCC Clinical Studies Unit

    Birmingham, Alabama, 35233-2115

  • Department of Veterans Affairs Medical Center

    Birmingham, Alabama, 35233

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35233

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35294

  • Cancer Treatment & Research Center

    Bismarck, North Dakota, 58501

  • Odyssey Research

    Bismarck, North Dakota, 58501

  • The Center for Hematology/Oncology

    Boca Raton, Florida, 33486

  • Florida Cancer Specialists

    Bonita Springs, Florida, 34135

  • Florida Cancer Specialists

    Bradenton, Florida, 34209

  • East Valley Hematology Oncology Medical Group

    Burbank, California, 91505

  • Providence Saint Joseph Medical Center

    Burbank, California, 91505

  • Florida Cancer Specialists

    Cape Coral, Florida, 33990

  • Raleigh Hematology Oncology Associates

    Cary, North Carolina, 27511

  • Raleigh Hematology Oncology Association

    Cary, North Carolina, 27511

  • Medical University of S.C.

    Charleston, South Carolina, 29425

  • Carolinas HealthCare System/Carolinas Medical Center

    Charlotte, North Carolina, 28203

  • Carolinas Hematology-Oncology Associates

    Charlotte, North Carolina, 28203

  • Chattanooga Oncology & Hemtology Associates, P. C.

    Chattanooga, Tennessee, 37404

  • Memorial Hospital

    Chattanooga, Tennessee, 37404

  • Swedish Covenant Cancer Center

    Chicago, Illinois, 60625

  • Marilyn Norton, M. D.

    Chula Vista, California, 91911

  • Rosalba Rodriquez, M. D.

    Chula Vista, California, 91911

  • Hitesh Patel

    Clearwater, Florida, 33756

  • Joseph DeFelice

    Clearwater, Florida, 33756

  • Morton Plant Hospital

    Clearwater, Florida, 33756

  • Oncology Physicians

    Clearwater, Florida, 33756

  • Oncology Physicians

    Clearwater, Florida, 33761

  • Case Western Reserve University- University Hospitals of Cleveland

    Cleveland, Ohio, 44106

  • Space Coast Medical Associates

    Cocoa Beach, Florida, 32931

  • Boone Hospital Center

    Columbia, Missouri, 65201

  • Missouri Cancer Associates

    Columbia, Missouri, 65201

  • Ellis Fischel Cancer Center - University of Missouri Health Care

    Columbia, Missouri, 65203

  • Mid Ohio Oncology/Hematology, Inc.

    Columbus, Ohio, 43213

  • Mid Ohio Oncology/Hematology, Inc.

    Columbus, Ohio, 43215

  • Mid Ohio Oncology/Hematology

    Columbus, Ohio, 43222

  • Bay Area Cancer Research Group

    Concord, California, 94520

  • Dallas Oncology Consultants, PA

    Dallas, Texas, 75208

  • Center for Oncology Research and Treatment, PA

    Dallas, Texas, 75230

  • Texas Cancer Associates, LLP

    Dallas, Texas, 75231

  • Dallas Oncology Consultants, PA

    Dallas, Texas, 75237

  • Genesis Health System

    Davenport, Iowa, 52803

  • Cancer Care Specialists of Central IL

    Decatur, Illinois, 62526

  • Decatur Memorial Hospital/Clinical Research

    Decatur, Illinois, 62526

  • The Center for Hematology/Oncology

    Delray Beach, Florida, 33484

  • Duluth Clinic

    Duluth, Minnesota, 55805

  • Regional Hematology Oncology Associates

    Durham, North Carolina, 27704

  • Regional Hematology Oncology Association

    Durham, North Carolina, 27704

  • Cancer Centers of the Carolinas

    Easley, South Carolina, 29640

  • Central Jersey Oncology Center

    East Brunswick, New Jersey, 08816

  • North Shore Hematology Oncology Associates, P.C.

    East Setauket, New York, 11733

  • Cancer Care Specialists of Central IL

    Effingham, Illinois, 62401

  • Elkhart General Hospital

    Elkhart, Indiana, 46514

  • VLCC-Elkhorn

    Elkhorn, Wisconsin, 53121

  • Community Health Partners, Ireland Cancer Center

    Elyria, Ohio, 44035

  • Dakota Cancer Institute

    Fargo, North Dakota, 58103

  • Odyssey Research

    Fargo, North Dakota, 58103

  • Highlands Oncology Group

    Fayetteville, Arkansas, 72703

  • Peachtree Hematology & Oncology Consultants, P. C.

    Fayetteville, Georgia, 30214

  • Northwest Medical Specialists, PLLC

    Federal Way, Washington, 98003

  • Joliet Oncology-Hematology Associates, Ltd.

    Flossmoor, Illinois, 60422

  • Broward Oncology Associates

    Fort Lauderdale, Florida, 33308

  • Florida Cancer Specialists

    Fort Myers, Florida, 33901

  • Florida Cancer Speicalists

    Fort Myers, Florida, 33901

  • Florida Cancer Specialists

    Fort Myers, Florida, 33908

  • Texas Oncology, P.A.

    Fort Worth, Texas, 76104

  • Southwest Fort Worth Cancer Center

    Fort Worth, Texas, 76132

  • The Consultant Group, P.C.

    Franklin, Tennessee, 37067

  • Queens Medical Associates

    Fresh Meadows, New York, 11365

  • Galesburg Cottage Hospital

    Galesburg, Illinois, 61401

  • Medical & Surgical Specialists, LLC

    Galesburg, Illinois, 61401

  • St. Mary Medical Center

    Galesburg, Illinois, 61401

  • The Sarah Cannon Cancer Center/Tennessee Oncology, PLLC

    Gallatin, Tennessee, 37066

  • Gaston Hematology & Oncology Associates

    Gastonia, North Carolina, 28054

  • Palo Verde Hematology Oncology

    Glendale, Arizona, 85304

  • Wilshire Oncology Medical Group, Inc.

    Glendora, California, 91741

  • Center for Cancer CAre at Goshen Health System

    Goshen, Indiana, 46526

  • Cancer Centers of the Carolinas

    Greenville, South Carolina, 29605

  • Cancer Centers of the Carolinas

    Greenville, South Carolina, 29615

  • Cancer Centers of the Carolinas

    Greenwood, South Carolina, 29646

  • Medical Oncology & Hematology, P. C.

    Hamden, Connecticut, 06518

  • The Sarah Cannon Cancer Center/Tennessee Oncology, PLLC

    Hermitage, Tennessee, 37076

  • South Florida Oncology Hematology

    Hollywood, Florida, 33021

  • Straub Clinic & Hospital

    Honolulu, Hawaii, 96813

  • Kapiolani Medical Center for Women & Children

    Honolulu, Hawaii, 96826

  • Heritage Physician Group, Oncology

    Hot Springs, Arkansas, 71913

  • The University of Texas - M. D. Anderson Cancer Center

    Houston, Texas, 77030

  • Indiana University Cancer Center

    Indianapolis, Indiana, 46202

  • Indiana University-Clarian Health Partners

    Indianapolis, Indiana, 46202

  • Veterans Administration

    Indianapolis, Indiana, 46202

  • Wishard Hospital

    Indianapolis, Indiana, 46202

  • Florida Oncology Associates

    Jacksonville, Florida, 32204

  • Florida Oncology Associates

    Jacksonville, Florida, 32207

  • Shands Jacksonville

    Jacksonville, Florida, 32209

  • University of Florida/Jacksonville Faculty Clinic

    Jacksonville, Florida, 32209

  • Florida Oncology Associates

    Jacksonville, Florida, 32218

  • Florida Oncology Associates

    Jacksonville, Florida, 32223

  • Florida Oncology Associates

    Jacksonville Beach, Florida, 32250

  • Cancer Care Center

    Jeffersonville, Indiana, 47130

  • Joliet Oncology-Hematology Associates, Ltd.

    Joliet, Illinois, 60435

  • Freeman Cancer Institute

    Joplin, Missouri, 64804

  • Freeman Health System

    Joplin, Missouri, 64804

  • Kansas City Cancer Center

    Kansas City, Kansas, 66112

  • Kansas City Cancer Center

    Kansas City, Missouri, 64111

  • Kansas City Cancer Center

    Kansas City, Missouri, 64131

  • Kansas City Cancer Center

    Kansas City, Missouri, 64154

  • Associates in Oncology/Hematology, P.C.

    Kensington, Maryland, 20895

  • Thompson Oncology Group

    Knoxville, Tennessee, 37916

  • Baptist Hospital of East Tennessee

    Knoxville, Tennessee, 37920

  • East Tennessee Oncology/Hematology, P.C.

    Knoxville, Tennessee, 37920

  • Baptist Hospital West

    Knoxville, Tennessee, 37922

  • East Tennessee Oncology/Hematology, P.C.

    Knoxville, Tennessee, 37922

  • Thompson Oncology Group

    Knoxville, Tennessee, 37932

  • Grossmont Hospital

    La Mesa, California, 91942

  • Sharp Rees-Stealy

    La Mesa, California, 91942

  • LaPorte Hospital

    La Porte, Indiana, 46350

  • Wilshire Oncology Medical Group, Inc.

    La Verne, California, 91750

  • Deerpath Medical Associates

    Lake Forest, Illinois, 60045

  • Lakeland Regional Cancer Center

    Lakeland, Florida, 33805

  • Lakeland Regional Medical Center

    Lakeland, Florida, 33805

  • Northwest Medical Specialties, PLLC

    Lakewood, Washington, 98499

  • Sparrow Health System

    Lansing, Michigan, 48909

  • Sparrow Health System

    Lansing, Michigan, 48912

  • Nevada Cancer Centers

    Las Vegas, Nevada, 89109

  • Nevada Cancer Centers

    Las Vegas, Nevada, 89128

  • New York Oncology Hematology, P.C.

    Latham, New York, 12110

  • The Sarah Cannon Cancer Center/Tennessee Oncology, PLLC

    Lebanon, Tennessee, 37087

  • Kansas City Cancer Center

    Lee's Summit, Missouri, 64064

  • North Shore Oncology Hematology Associates

    Libertyville, Illinois, 60048

  • University of Arkansas for Medical Sciences

    Little Rock, Arkansas, 72205

  • Alice Hyde Medical Center

    Malone, New York, 12953

  • Myrna Sanchez, MD

    Malone, New York, 12953

  • Thompson Oncology Group

    Maryville, Tennessee, 37804

  • North Shore Oncology Hematology Associates

    McHenry, Illinois, 60050

  • Medical Oncology & Hematology, P.C.

    Meriden, Connecticut, 06451

  • Space Coast Medical Associates

    Merritt Island, Florida, 32952

  • Medical Consultants, Ltd.

    Milwaukee, Wisconsin, 53215

  • North Valley Hematology Oncology Group

    Mission Hills, California, 91345

  • Providence Holy Cross Medical Center

    Mission Hills, California, 91345

  • Clinical Trials and Research Associates, Inc.

    Montebello, California, 60460

  • Beverly Oncology & Imaging

    Montebello, California, 90640

  • Beverly Oncology and Imaging Center, Inc.

    Montebello, California, 90640

  • Clinical Trials & Research Associates, Inc.

    Montebello, California, 90640

  • Oncology Care Medical Associates, Inc.

    Montebello, California, 90640

  • Joliet Oncology-Hematology Associates, Ltd.

    Morris, Illinois, 60450

  • Medical Consultants, PC

    Muncie, Indiana, 47303

  • The Sarah Cannon Cancer Center/Tennessee Oncology, PLLC

    Murfreesboro, Tennessee, 37130

  • Florida Cancer Specialists

    Naples, Florida, 34102

  • Florida Cancer Specialists

    Naples, Florida, 34119

  • The Sarah Cannon Cancer Center

    Nashville, Tennessee, 37203

  • The Consultant Group, P.C.

    Nashville, Tennessee, 37205

  • The Sarah Cannon Cancer Center/Tennessee Oncology, PLLC

    Nashville, Tennessee, 37205

  • The Sarah Cannon Cancer Center/Tennessee Oncology, PLLC

    Nashville, Tennessee, 37207

  • The Sarah Cannon Cancer Center/Tennessee Oncology, PLLC

    Nashville, Tennessee, 37211

  • Shore Cancer Center

    Nassawadox, Virginia, 23413

  • Cancer Care Center

    New Albany, Indiana, 47150

  • Ball Cancer Center at Forest Ridge Medical Pavilion

    New Castle, Indiana, 47362

  • Medical Oncology & Hematology, P. C.

    New Haven, Connecticut, 06510

  • Medical Oncology & Hematology, P. C.

    New Haven, Connecticut, 06511

  • New Milford Hospital

    New Milford, Connecticut, 06776

  • Northwestern Connecticut Oncology/Hematology

    New Milford, Connecticut, 06776

  • University Hospital

    Newark, New Jersey, 07103

  • Lakeland Hospital

    Niles, Michigan, 49120

  • Cancer Care Associates

    Norman, Oklahoma, 73071

  • Cumberland Oncology & Hematology

    Oak Ridge, Tennessee, 37830

  • Mohammad Kamal, M. D.

    Ocala, Florida, 34471

  • Ocala Research Institute, Inc.

    Ocala, Florida, 34480

  • N. County Oncology Medical

    Oceanside, California, 92056

  • Cancer Care Associates

    Oklahoma City, Oklahoma, 73102

  • Cancer Care Associates

    Oklahoma City, Oklahoma, 73109

  • Cancer Care Associates

    Oklahoma City, Oklahoma, 73112

  • Cancer Care Associates

    Oklahoma City, Oklahoma, 73120

  • Nebraska Methodist Hospital

    Omaha, Nebraska, 68114

  • UHHS Chagrin Highlands - Ireland Cancer Center

    Orange, Ohio, 44122

  • Florida Oncology Associates

    Orange Park, Florida, 32073

  • Florida Hospital

    Orlando, Florida, 32603

  • Hematology & Oncology Consultants, PA

    Orlando, Florida, 32804

  • Moroose, Reynolds, Castillo, Robinson & Lukman, MD, PA

    Orlando, Florida, 32804

  • Florida Hospital Memorial Division, Cancer Care Center

    Ormond Beach, Florida, 32174

  • Kansas City Cancer Center

    Overland Park, Kansas, 66210

  • Florida Oncology Associates

    Palatka, Florida, 32177

  • Palm Beach Cancer Institute

    Palm Beach Gardens, Florida, 33410

  • Wilshire Oncology Medical Group, Inc.

    Pasadena, California, 91105

  • Hospital of the University of Pennsylvania

    Philadelphia, Pennsylvania, 19104

  • Greater Philadelphia Cancer and Hematology Specialists, PC

    Philadelphia, Pennsylvania, 19114

  • Wilshire Oncology Medical Group, Inc.

    Pomona, California, 91767

  • Florida Cancer Specialists

    Port Charlotte, Florida, 33980

  • Hematology/Oncology Associates of The Treasure Coast

    Port Saint Lucie, Florida, 34952

  • Kaiser Permanente Northwest Region

    Portland, Oregon, 97227

  • Raleigh Hematology Oncology Associates

    Raleigh, North Carolina, 27607

  • Raleigh Hematology Oncology Association

    Raleigh, North Carolina, 27607

  • Raleigh Hematology Oncology Associates

    Raleigh, North Carolina, 27609

  • Raleigh Hematology Oncology Association

    Raleigh, North Carolina, 27609

  • Wilshire Oncology Medical Group, Inc.

    Rancho Cucamonga, California, 91730

  • Center for Oncology Research and Treatment, PA

    Richardson, Texas, 75080

  • Associates in Oncology/Hematology, P.C.

    Rockville, Maryland, 20850

  • Florida Oncology Associates

    Saint Augustine, Florida, 32086

  • Lakeland Hospital

    Saint Joseph, Michigan, 49085-2158

  • Southern California Permanente Medical Group

    San Diego, California, 92120

  • Medical Oncology Associates - SD

    San Diego, California, 92123

  • Sharp Memorial Hospital

    San Diego, California, 92123

  • Sharp Rees-Stealy

    San Diego, California, 92123

  • Oncology Care Medical Associates, Inc.

    San Gabriel, California, 91776

  • East Bay Medical Oncology/Hematology Medcial Associates, Inc.

    San Leandro, California, 94578

  • Santa Monica Hematology/Oncology

    Santa Monica, California, 90404

  • Florida Cancer Specialists

    Sarasota, Florida, 34232

  • Florida Cancer Specialists

    Sarasota, Florida, 34236

  • Guthrie Clinic

    Sayre, Pennsylvania, 18840

  • Robert Packer Hospital

    Sayre, Pennsylvania, 18840

  • Horizons West Medical Group

    Scottsbluff, Nebraska, 69361

  • Cancer Centers of the Carolinas

    Seneca, South Carolina, 29672

  • Northwestern Connecticut Oncology/Hematology

    Sharon, Connecticut, 06069

  • Sharon Hospital

    Sharon, Connecticut, 06069

  • Hematology Oncology Associates of Illinois (HOAI)

    Skokie, Illinois, 60076

  • Midwest Cancer Research Group, Inc.

    Skokie, Illinois, 60076

  • North Shore Cancer Research Association

    Skokie, Illinois, 60076

  • Aurora Health Center-Slinger

    Slinger, Wisconsin, 53086

  • The Sarah Cannon Cancer Center/Tennessee Oncology, PLLC

    Smyrna, Tennessee, 37167

  • Memorial Hospital of South Bend

    South Bend, Indiana, 46601

  • Saint Joseph's Regional Medical Center

    South Bend, Indiana, 46617

  • Cancer Centers of the Carolinas

    Spartanburg, South Carolina, 29307

  • Highlands Oncology Group

    Springdale, Arkansas, 72764

  • Missouri Baptist Medical Center

    St Louis, Missouri, 63131

  • Northwest Medical Specialists, PLLC

    Tacoma, Washington, 98405

  • Albert Einstein Cancer Center at the Montefiore Medical Park

    The Bronx, New York, 10461

  • The Jack D. Weiler Hospital of the Albert Einstein College of Medicine

    The Bronx, New York, 10461

  • Montefiore Medical Center

    The Bronx, New York, 10467

  • Charlotte Hungerford Hospital

    Torrington, Connecticut, 06790

  • Northwestern Connecticut Oncology/Hematology

    Torrington, Connecticut, 06790

  • Cancer Care Associates

    Tulsa, Oklahoma, 74104

  • Cancer Care Associates

    Tulsa, Oklahoma, 74133

  • Cancer Care Associates

    Tulsa, Oklahoma, 74136

  • Florida Cancer Specialists

    Venice, Florida, 34285

  • Florida Cancer Specialists

    Venice, Florida, 34292

  • Medical Center of Vincennes

    Vincennes, Indiana, 47591

  • Tricare

    Vincennes, Indiana, 47591

  • Cooper Cancer Institute

    Voorhees Township, New Jersey, 08043

  • Diablo Valley Oncology & Hematology Medical Group, Inc.

    Walnut Creek, California, 94598

  • Georgetown University Hospital

    Washington D.C., District of Columbia, 20007

  • Washington Hospital Center - Washington Cancer Institute

    Washington D.C., District of Columbia, 20010

  • Medical Oncology & Hematology, P.C.

    Waterbury, Connecticut, 06708

  • Palm Beach Cancer Institute

    Wellington, Florida, 33414

  • VLCC-West Bend

    West Bend, Wisconsin, 53095

  • Wilshire Oncology Medical Group, Inc.

    West Covina, California, 91790

  • Palm Beach Cancer Institute

    West Palm Beach, Florida, 33401

  • Mid Ohio Oncology/Hematology, Inc.

    Westerville, Ohio, 43081

  • UHHS Westlake - Ireland Cancer Center

    Westlake, Ohio, 44145

  • Oncology Care Medical Associates, Inc.

    Whittier, California, 90602

  • Piedmont Hematology Oncology Associates

    Winston-Salem, North Carolina, 27103

  • Hematology & Oncology Consultants, PA

    Winter Park, Florida, 32792

  • Department of Hematology/Oncology

    Worcester, Massachusetts, 01608

  • Fallon Clinic Pharmacy-Linda Tolf, R.Ph.

    Worcester, Massachusetts, 01608

  • Saint Vincent Hospital/Worcester Medical Center-Paul Seed, R.Ph.D

    Worcester, Massachusetts, 01608

  • Midwestern Regional Medical Center

    Zion, Illinois, 60099

Other trials in United States

Brazil17 sites

  • Hospital Vera Cruz

    Belo Horizonte, Minas Gerais, 30180-090

  • Hospital das Clinicas da UFPR

    Curitiba, Paraná, 80060-150

  • Pro Onco Centro de Tratamento Oncologico S/C Ltda.

    Curitiba, Paraná, 86010-640

  • Instituto do Cancer do Ceara

    Fortaleza, Ceará, 60430-230

  • Associacao de Combate ao cancer de Goias - Hospital

    Goiânia, Goiás, 74605-070

  • Hospital Sao Lucas - PUCRS

    Porto Alegre, Rio Grande do Sul, 90610-000

  • Hospital Sao Lucas-PUCRS

    Porto Alegre, Rio Grande do Sul, 90610-000

  • Nucleo de Oncologia da Bahia

    Salvador, Estado de Bahia, 40170-070

  • Santo Andre Diagnostico e Tratamento Ltda

    Santo André, São Paulo, 09090-780

  • Santo Andre Diagnosticos e Tratamentos Ltda.

    Santo André, São Paulo, 09090-780

  • Santo Andre Diagnosticos e Tratamentos

    Santo André, São Paulo, 09090-780

  • Instituto do Cancer Arnaldo Vieira de Carvalho

    São Paulo, São Paulo, 01224-010

  • Complexo Hospitalar Heliopolis

    São Paulo, São Paulo, 01327-002

  • Universidade Federal de Sao Paulo - UNIFESP/EPM

    São Paulo, São Paulo, 04039-032

  • Hospital das Clinicas - Universidade de Sao Paulo

    São Paulo, São Paulo, 05403-000

  • Fundacao Pio XII - Hospital do Cancer de Barretos

    São Paulo, São Paulo, 14784-400

  • Conjunto Hospitalar de Sorocaba

    São Paulo, São Paulo, 18030-210

Other trials in Brazil

Australia14 sites

  • Albury Base Hospital

    Albury, New South Wales, 2640

  • West Albury Barker's Pharmacy

    Albury, New South Wales, 2640

  • Bankstown Lidcombe Hospital - Department of Medical Oncology

    Bankstown, 2200

  • Flinders Medical Centre

    Bedford Park, South Australia, 5041

  • St. Vincent's Hospital

    Fitzroy, Victoria, 3065

  • Royal Hobart Hospital

    Hobart, 7000

  • Sir Charles Gairdner Hospital

    Nedlands, 6009

  • Department Of Oncology

    South Brisbane, Queensland, 4101

  • Royal North Shore Hospital-Medical Oncology Dept.

    St Leonards, 2065

  • Department of Medical Oncology-Newcastle Mater Misericordiae Hospital

    Waratah, New South Wales, 2298

  • Pharmatel Fresenius Kabi Pty Ltd.

    West Melbourne, Victoria, 3003

  • Murray Valley Private Hospital

    Wodonga, Victoria, 3690

  • Border Medical Oncology - Murray Valley Private Hospital

    Wodonga, 3690

  • Clinical Trials Centre - Wollongong Hospital

    Wollongong, 2500

Other trials in Australia

Argentina13 sites

  • Policlinica Privada Instituto de Medicina Nuclear

    Bahía Blanca, Buenos Aires, B8000LMA

  • Instituto Alexander flaming

    Buenos Aires, Buenos Aires, C1426ANZ

  • Complejo Medico de la Policia Federal Argentina "Churruca-Visca" - Servicio de Oncologia

    Buenos Aires, 1437

  • Hospital General de Agudos "Carlos G. Durand" - Servicio de Oncologia

    Buenos Aires, C1405DCS

  • Hospital Britanico de Buenos Aires

    Capital Federal, Buenos Aires, C1280AEB

  • Hospital de Oncologia Maria Curie

    Capital Federal, Buenos Aires, C1405BWU

  • Hospital Alvarez

    Capital Federal, Buenos Aires, C1406FWY

  • Hospital Donacion F. Santojanni

    Capital Federal, Buenos Aires, C1408INH

  • Hospital Privado de Comunidad

    Córdoba, Mar Del Plata, 7602

  • Sociedad de Beneficencia Hospital Italiano

    Córdoba, 5000

  • Hospital Universitario Austral - Servicio de Oncologia

    Pilar, Buenos Aires, 1629

  • Instituto CAICI

    Rosario, 2000

  • H.I.G.A. Eva Peron

    San Martin, 1650

Other trials in Argentina

Chile9 sites

  • Departmento de Hemato-Oncologia

    Santiago, Las Condes

  • Clinica Las Condes

    Santiago

  • Clinica Santa Maria

    Santiago

  • FundacionArturo Lopez Perez

    Santiago

  • Hospital Clinico Universidad de Chile

    Santiago

  • Hospital FACH

    Santiago

  • Hospital Militar

    Santiago

  • Instituto Nacional del Cancer - Servicio de Radioterapia

    Santiago

  • Instituto Nacional del Cancer

    Santiago

Other trials in Chile

Germany9 sites

  • Stadtisches Krankenhaus Martha-Maria Halle-Dolau GmbH

    Haale, 06120

  • Allgemeines Kraken Haus St. Georg Onkologie

    Hamburg, 20099

  • IORC GmbH

    Hamburg, 22081

  • Thoraxklinik-Heidelberg GmbH

    Heidelberg, Rohrbach BW, 69126

  • Laborgemeinschaft Hamburg

    Lademannbogen 8, Free and Hanseatic City of Hamburg, 22339

  • Allgemeines Krankenhaus St. Georg

    Lohmuehlstr.5, Free and Hanseatic City of Hamburg, 20099

  • Askllepios Fachkliniken

    Robert-Koch-Allee 2, Gauting, 82131

  • St. Vincentius-Kliniken gAG

    Sudendstrasse 32, Karlshure, 76147

  • KH GroBhansdorf - Abt. fuer Thoraxonkologie

    Woehrendamm 80, Grosshansdorf, 22927

Other trials in Germany

Italy3 sites

  • Azienda Ospedaliera di Parma - U.O. di Oncologia

    Parma, 43100

  • Ospedale "Carlo Poma" - Divisione di Oncologia Medica ed

    Via Albertoni, Mantova, 46100

  • Ospedale Garibaldi di Nesima - Oncologia Medica

    Via Palermo, Catania, 95122

Other trials in Italy

United Kingdom3 sites

  • Bristol Haemotolgy and Oncology Centre

    Bristol, BA21 4AT

  • Div. of cancer Medicine - Princess Alexandra Centre-Ninewells Hospital & Medical School

    Dundee, DD1-9SY

  • Department of Medical Oncology

    West Smithfield, London, EC1A 7BE

Other trials in United Kingdom

About this study

Official title: Phase 3 Randomized Study of TLK286 (Telcyta) Versus Gefitinib (Iressa) as Third-Line Therapy in Locally Advanced or Metastatic Non-Small Cell Lung Cancer

The purpose of this study is to determine if TLK286(Telcyta) is more effective than gefitinib (Iressa) in the treatment of non-small cell lung cancer.

Being tested
TLK286 (Telcyta) HCl for Injection, gefitinib (Iressa)
Medical subject headings
Carcinoma, Non-Small-Cell Lung

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • TLK286 (Telcyta) HCl for InjectionDrug

  • gefitinib (Iressa)Drug

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted30 Mar 2004 (estimated)
  2. Study completionMay 2005

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase 3
Primary purpose
Treatment
Allocation
Randomised
Intervention model
Parallel groups
Masking
None (open label)
Enrolment
520 participants
IDs, dates and publications
ClinicalTrials.gov ID
NCT00080340
Sponsor's protocol ID
TLK286.3020
Status last verified
Mar 2006
First submitted
26 Mar 2004
Last updated
15 Jan 2008
Results posted
No

Questions about this trial

What is this clinical trial studying?

A Phase 3 study testing TLK286 (Telcyta) HCl for Injection and gefitinib (Iressa) in people with Non Small Cell Lung Carcinoma, run by Telik at 338 sites in 8 countries.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 4 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 15 Jan 2008. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 338 sites in United States, Brazil, Australia, Argentina, Chile and 3 more countries. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

What does this phase mean?

Phase 3 studies compare the treatment with the current standard treatment or a placebo in a large group, to confirm how well it works and watch for side effects.

Not every study follows the same path, and some studies (observational studies, device studies) have no phase.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT00080340.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Jan 2008.

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