Research institution
Xiangya Hospital of Central South University Clinical Trials
Studies where Xiangya Hospital of Central South University is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 141Breastfeeding Rates
Development and Implementation of a Breastfeeding Program for Post-Cesarean Section Women Based on the 5A Nursing Model
Develop and apply a breastfeeding program for postoperative mothers of cesarean section based on the 5A nursing model, and evaluate its impact on the mothers' mastery of breastfeeding knowledge, self-efficacy, breastfeeding rate…
- Trial name
- NCT07913438
- Testing
- Based on the 5A nursing intervention plan, Implement routine care
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Postoperative Delirium
Acetaminophen-Mannitol Injection and Postoperative Delirium
The aim of this multicenter randomized controlled study is to evaluate the effect of an intravenous acetaminophen-mannitol opioid-sparing analgesic strategy on the cumulative incidence of POD, compared with an intravenous…
- Trial name
- PAPOD-ES (NCT07235995)
- Testing
- Acetaminophen group, Sufentanil group
- Where
- China
- Volunteers
- 1,092 people
- Sponsor
- Xiangya Hospital of Central South University
Schizophrenia, Antipsychotic Induced Weight Gain
A Relation Between Craving Induction and Treatment Response in Deep Transcranial Magnetic Stimulation (dTMS) for Reducing Antipsychotic-induced Weight Gain in Schizophrenia
Antipsychotic-induced metabolic disturbances, especially weight gain, are common in patients with schizophrenia. Furthermore, it is reported significant changes in food intake happened in patients with weight gain after intaking…
- Trial name
- dTMS (NCT07805980)
- Testing
- Deep Transcranial Magnetic Stimulation (dTMS) H4 coil - Active
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Second Xiangya Hospital of Central South University
Schizophrenia Spectrum, Schizophrenia
The Safety and Effectiveness of dTMS for Reducing Antipsychotic-induced Weight Gain
Antipsychotic-induced metabolic disturbances, especially weight gain, are common in patients with schizophrenia. There are no hitherto effective treatments for reducing antipsychotic-induced weight gain.
- Conditions
- Schizophrenia Spectrum, Schizophrenia, Antipsychotic Induced Weight Gain
- Trial name
- dTMS (NCT07795554)
- Testing
- dTMS of accelerated intermittent theta burst stimulation, ACC-iTBS
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Second Xiangya Hospital of Central South University
Chronic Insomnia Disorder
Online Tai Chi Versus Digital CBT-I for Chronic Insomnia
This multicenter randomized controlled trial will compare online Tai Chi (OTC) with digital cognitive behavioral therapy for insomnia (dCBT-I) in adults with chronic insomnia disorder.
- Trial name
- NCT07853651
- Testing
- Online Tai Chi, Digital Cognitive Behavioral Therapy for Insomnia
- Where
- China
- Volunteers
- 172 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Drug Interactions
Effect of Itraconazole on the Pharmacokinetics of Intravenous HRS-4642 in Healthy Participants
This is a Phase 1, single-center, open-label study designed to evaluate the effect of itraconazole on the pharmacokinetics of HRS-4642 in healthy adult participants. Approximately 18 healthy participants will be enrolled.
- Trial name
- NCT07894679
- Testing
- HRS-4642, Itraconazole (200 mg)
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- The Third Xiangya Hospital of Central South University
Healthy Volunteers
A Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single Intravenous Doses of NH302 Injection in Healthy Participants
This is a first-in-human study of NH302 injection in healthy participants. The study will test single intravenous doses of NH302 to evaluate its safety and tolerability, how the body processes NH302, and its effects on selected…
- Trial name
- NCT07892469
- Testing
- NH302 injection
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- The Third Xiangya Hospital of Central South University
Type 2 Diabetes Mellitus
Preventive Effectiveness of Primary Care Physician-led CGM-supported Comprehensive Intervention on Cardio-metabolic-immune Diseases in Community Patients With Type 2 Diabetes (Community Diabetes Control Project)
This community-based trial evaluates whether primary care physicians, equipped with continuous glucose monitoring (CGM) and trained under a standardized protocol with specialist backup, can improve diabetes outcomes through…
- Trial name
- CDCP (NCT07885904)
- Testing
- comprehensive intervention
- Where
- China
- Volunteers
- 15,400 people
- Sponsor
- Xiangya Hospital of Central South University
Resectable Non-Small-Cell Lung Cancer
Propranolol Hydrochloride Combined With Toripalimab and Platinum-based Chemotherapy in Resectable Non-Small Cell Lung Cancer
This is a prospective, multicenter, open-label study designed to evaluate the safety and tolerability of propranolol hydrochloride in combination with toripalimab and platinum-based chemotherapy as perioperative treatment in…
- Trial name
- NeoBRIO (NCT07886229)
- Testing
- Propranolol Hydrochloride, Toripalimab, Chemotherapy
- Where
- 4 sites in China
- Volunteers
- 9 people
- Sponsor
- Second Xiangya Hospital of Central South University
Small Cell Lung Cancer (SCLC)
Propranolol Hydrochloride Combined With Adebrelimab and Platinum-Based Chemotherapy in Small Cell Lung Cancer
This is a prospective multicenter, open-label, Phase I clinical study designed to evaluate the safety, tolerability, and preliminary efficacy of propranolol hydrochloride in combination with adebrelimab and platinum-based…
- Trial name
- BRIO-SCLC (NCT07886047)
- Testing
- Propranolol Hydrochloride, Adebrelimab, Chemotherapy
- Where
- 4 sites in China
- Volunteers
- 18 people
- Sponsor
- Second Xiangya Hospital of Central South University
Completed, with results posted
All 2Chronic Pruritus
Treatment of Chronic Itch in Patients Under Arsenic Exposure With Naloxone
The purpose of this study is to assess the efficacy and safety of sublingual naloxone in the treatment of chronic itch in patients under arsenic exposure.
- Trial name
- NCT03751111
- Testing
- Naloxone
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Xiangya Hospital of Central South University
Osteoarthritis
MRI of Infrapatellar Fat Pad in Osteoarthritis
In this study, the investigators use the clinical documentation and imaging data of MRI to do research. Clinical subjects were divided into two groups: osteoarthritis patients and healthy controls without osteoarthritis.
- Trial name
- IPFP-MRI (NCT02829463)
- Testing
- Magnetic resonance imaging
- Where
- China
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- The Third Xiangya Hospital of Central South University