Research institution
University of Cincinnati Clinical Trials
Studies where University of Cincinnati is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 37Type 2 Diabetes
Transitioning Recently Admitted Patients With Non-Insulin and Insulin-treated Type 2 Diabetes to Innovative Glucose Monitoring
The TRANSITION-CGM trial will evaluate whether starting continuous glucose monitoring (CGM) before hospital discharge improves blood glucose control in adults with type 2 diabetes compared with usual care using finger-stick blood…
- Trial name
- TRANSITION-CGM (NCT07890818)
- Testing
- Continuous glucose monitor
- Where
- United States
- Volunteers
- 218 people
- Sponsor
- University of Cincinnati
Sickle Cell Disease (SCD)
Self-administered Acupressure in Patients With Sickle Cell Disease
The proposed research is to determine the clinical efficacy and neurobiological mechanisms of acupressure analgesia in patients with sickle cell disease (SCD).
- Trial name
- NCT07875777
- Testing
- Verum Acupressure (using AcuWand)
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Cincinnati
Posttraumatic Stress Symptoms, Heavy Alcoholic Consumption
Self-administered Neurostimulation Intervention for Firefighter Traumatic Stress to Reduce Alcohol Use: Pilot Study
The goal of this clinical trial is to evaluate the feasibility, acceptability, and appropriateness of a transcutaneous auricular neurostimulation (tAN) protocol in firefighters who engage in heavy drinking, have at least a mild…
- Conditions
- Posttraumatic Stress Symptoms, Heavy Alcoholic Consumption, Alcohol Use Disorder (AUD)
- Trial name
- SANI-T (NCT07868055)
- Testing
- Transcutaneous auricular neurostimulation (tAN)
- Volunteers
- 20 people
- Sponsor
- University of Cincinnati
Dysphagia, Dysphagia, Oropharyngeal
K01 Impacts of Lingual Endurance Exercise
The goal of this clinical trial is to learn whether a tongue endurance exercise program can improve swallowing function in adults with dysphagia after a stroke.
- Conditions
- Dysphagia, Dysphagia, Oropharyngeal, Ischemic Stroke, Stroke
- Trial name
- NCT06072924
- Testing
- Isotonic Endurance Exercise
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Cincinnati
Chemotherapy Exposure, Handling Guidelines
Promoting Adherence to Chemotherapy Handling Guidelines Among Oncology Nurses
Chemotherapy exposure is a serious occupational hazard affecting oncology nurses. Oncology nurses' adherence to chemotherapy handling guidelines is essential to prevent their exposure to chemotherapy.
- Conditions
- Chemotherapy Exposure, Handling Guidelines, Oncology Nurse, Adherence
- Trial name
- NCT06919653
- Testing
- The Workplace program to Improve the Safe Handling of hazardous drugs (WISH)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Stroke, Stroke, Acute
Treatment With Endovascular Intervention for STroke Patients With Existing Disability
TESTED will compare the risks and benefits of endovascular thrombectomy (EVT) to medical management (no EVT) in ischemic stroke patients who have a blockage in one of the large blood vessels in the brain and have a…
- Conditions
- Stroke, Stroke, Acute, Stroke, Ischemic
- Trial name
- TESTED (NCT05911568)
- Testing
- Endovascular Stroke Treatment, Medical Management
- Where
- 35 sites in United States
- Volunteers
- 1,060 people
- Sponsor
- University of Cincinnati
Ischemic Stroke
Post-Stroke Sensory Reweighting on Walking and Balance Outcomes
The primary objective of this proof-of-concept study is to longitudinally track the development of post-stroke sensory reweighting (PSR), identify associated structural neuroanatomical correlates, and investigate their…
- Trial name
- PSR (NCT06727097)
- Testing
- Posturography, Walking Speed, Instrumented 7M Timed UP and GO
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Cincinnati
Cystic Fibrosis
Hormonal Responses to a Mixed Meal in People With Cystic Fibrosis
In this exploratory study, the hormonal responses to a mixed meal will be examined in people with cystic fibrosis. The aim of this study is to find correlates with impaired glucose tolerance that is associated with this…
- Trial name
- NCT06163482
- Testing
- Mixed meal
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Eldery People, Cognitive Decline
Optimizing CNS DHA Delivery in Elderly Adults at Risk for Dementia
The purpose of this placebo-controlled trial is to compare the effects of 24-weeks supplementation with LPC-DHA and TAG-DHA on cerebrospinal fluid and blood DHA levels, as well as biomarkers of central neurodegenerative and…
- Conditions
- Eldery People, Cognitive Decline, Memory Decline, DHA CNS Delivery
- Trial name
- NCT06933095
- Testing
- LPC-EPA+DHA capsules containing omega-3 fatty acids EPA and DHA esterified to lysophosphatidylcholine (LPC-EPA+DHA)(Trade name: Lysoveta)
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- University of Cincinnati
Brain Tumor
Study of Letrozole in Recurrent Gliomas
The purpose of this study is to determine the ability of letrozole to penetrate the blood brain barrier and concentrate in gliomas.
- Trial name
- NCT03122197
- Testing
- Letrozole Oral Tablet, Temozolomide
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Cincinnati
Completed, with results posted
All 76Recurrent Head and Neck Cancer, Head and Neck Cancer
Durvalumab (MEDI4736) With Cetuximab in Previously Treated Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
The purpose of this research study is to test the combination of the anti-cancer drugs durvalumab, the study drug, and cetuximab as a treatment for metastatic or recurrent head and neck cancer.
- Conditions
- Recurrent Head and Neck Cancer, Head and Neck Cancer, Head and Neck Neoplasms, Metastatic Cancer
- Trial name
- NCT03691714
- Testing
- Durvalumab, Cetuximab
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Cincinnati
Binge-Eating Disorder, Circadian Rhythm Disorders
The Role of the Circadian System in Binge Eating Disorder
Binge eating disorder (BED) shows prominent circadian features that suggest a delay in circadian phase, and preliminary evidence shows binge eating may be responsive to chronobiological interventions, implicating a circadian…
- Trial name
- CHRONO-BE (NCT04724668)
- Testing
- Melatonin (3hrs before DLMO), Morning light version 1, Morning light version 2
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Renal Transplantation
Belatacept Early Steroid Withdrawal Trial
The study purpose is to determine the safety and efficacy of a belatacept-based immunosuppressive regimen (calcineurin inhibitor free) with alemtuzumab or rabbit antithymocyte globulin (rATG) induction and early glucocorticoid…
- Trial name
- NCT01729494
- Testing
- Alemtuzumab, rabbit antithymocyte globulin, Belatacept
- Where
- 8 sites in United States
- Volunteers
- 316 people
- Sponsor
- University of Cincinnati
Premature Infant Disease, Family Research
PREEMIE PROGRESS: A Family Management Program for Parents of Preterm Infants
The purpose of this study is to refine and pilot test a mobile health (mHealth), video-based family management program for parents of preterm infants hospitalized in the Neonatal Intensive Care Unit (NICU).
- Conditions
- Premature Infant Disease, Family Research, Parent-Child Relations, Self Efficacy
- Trial name
- NCT04638127
- Testing
- PREEMIE PROGRESS, Attention Control
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Dysphagia, Oral Phase, Stroke, Ischemic
Lingual Endurance Exercise in Treating Post-Stroke Dysphagia
Aim 1: Determine feasibility of lingual endurance training for individuals with persistent dysphagia after ischemic stroke. Primary outcome measures: % patient adherence (# of attempted repetitions/# prescribed repetitions) and %…
- Trial name
- NCT05523973
- Testing
- Lingual Endurance Training
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Cincinnati