Research institution
University Hospital, Toulouse Clinical Trials
Studies where University Hospital, Toulouse is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 177Hypotension
Norepinephrine in the Management of General Anesthesia-Induced Arterial Hypotension in Chronic Heart Failure Patients
Arterial hypotension is a frequent complication of general anesthesia and a significant contributor to postoperative complications.
- Trial name
- NORAFLOW (NCT06350929)
- Testing
- Cardiac output monitoring by the Starling™ SV Sebac®
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Toulouse
Endometriosis, Infertility
Endometriosis Transcriptomic Cell Atlas
Endometriosis is an estrogen-dependent, chronic inflammatory gynecologic disease affecting women of reproductive age, with a therapeutic wandering of 6 to 10 years.
- Trial name
- EDISON (NCT06502548)
- Testing
- Endometriosis, Tubal ligation or Hysterectomy
- Where
- France
- Volunteers
- 92 people
- Sponsor
- University Hospital, Toulouse
Prostate Cancer - Recurrent, Prostate Cancer (Diagnosis)
Analysis of the Performance of PSMA Emission Tomography in Patients With Prostate Cancer Treated With HIFU
There would appear to be a strong interest in functional nuclear imaging for assessing the response to focal PaC treatment. Investigator team hypothesise that the diagnostic performance of PSMA PET is noninferior to that of MRI…
- Trial name
- ECETEP (NCT07766122)
- Testing
- Nuclear imaging (PSMA PET) with intravenous injection of a radiotracer one year after treatment (focal therapy)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Anorexia Nervosa
Speech Groups for Children Living With a Sibling Who Suffers From Anorexia Nervosa
Anorexia nervosa (AN) is a complex mental disease with a huge impact on the patient's siblings life and well-being. Based on literature, group interventions for siblings of children suffering from a chronic disease could provide…
- Trial name
- EMA-FRaM (NCT06528158)
- Testing
- sibling group
- Where
- France
- Volunteers
- 24 people
- Sponsor
- University Hospital, Toulouse
Obstructive Sleep Apnea Syndrome
Predictive Factors for Occlusal Changes in Obstructive Sleep Apnea Treatment With Mandibular Advancement Appliance
This research addresses obstructive sleep apnea syndrome (OSAS), affecting 6-12% of French adults, often treated with mandibular advancement devices (MADs).
- Trial name
- APNEAMOUVE (NCT06576310)
- Testing
- Mandibular Advancement Device
- Where
- France
- Volunteers
- 118 people
- Sponsor
- University Hospital, Toulouse
Carotid Web
Familial Form of Carotid Web: a Doppler Ultrasound Study
There is no evidence of familial forms of carotid web. The aim of this study is to determine the prevalence of carotid web among relatives of patient with carotid web using carotid doppler ultrasound.
- Trial name
- Family-WEB (NCT06336083)
- Testing
- Doppler ultrasound
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Heart Failure, Cardiac Surgery
Discontinuation or Continuation of SGLT-2 Inhibitors Before Cardiac Surgery
SGLT-2 inhibitors are recommended treatments for managing heart failure patients. In cases of surgery, it is recommended to stop the treatment 3 days before surgery due to the risk of postoperative euglycemic diabetic…
- Trial name
- DISCO (NCT07766109)
- Testing
- treatment discontinuation, treatment continuation, ketone levels
- Where
- France
- Volunteers
- 434 people
- Sponsor
- University Hospital, Toulouse
Aphasia, Stroke
Effect of Anomia Rehabilitation Combined With Metacognitive Training in Patients With Chronic Vascular Aphasia
The postulate of this study is that rehabilitation combining linguistic and metacognitive training will result in a significant improvement in language performance correlated with changes in functional cerebral connectivity…
- Trial name
- METALEX (NCT06930131)
- Testing
- Semantic rehabilitation
- Where
- France
- Volunteers
- 18 people
- Sponsor
- University Hospital, Toulouse
PARKINSON DISEASE (Disorder)
Effect of Botulinum Toxin on Resting Tremor of the Refractory Upper Limb in Parkinsonians
Tremor is one of the most common symptoms in Parkinson Disease (PD), affecting almost 60% of patients. There is currently no specific treatment for tremor in PD, and 30% of patients develop drug-resistant tremor, making its…
- Trial name
- TOX PARK (NCT07822893)
- Where
- 2 sites in France
- Volunteers
- 39 people
- Sponsor
- University Hospital, Toulouse
Infusion of Ketamine in Severe Borderline Personality Disorder, Borderline Personality Disorder (BPD)
Ketamine Infusion for Symptomatic Improvement in Severe Borderline Personality Disorder
The main objective of this pilot study is to evaluate at D9 the evolution of BPD symptoms' intensity(scale BSL-23) in severe BPD patients, after two Ketamine infusions (0.5mg/kg at H0 and H24).
- Trial name
- BorderKET (NCT07099534)
- Testing
- IV Ketamine (0.5 mg/kg) Infusion - Two Doses Administered 24 Hours Apart for Severe Borderline Personality Disorder
- Where
- France
- Volunteers
- 38 people
- Sponsor
- University Hospital, Toulouse
Completed, with results posted
All 2COVID-19
Efficacy of Pre-exposure Treatment With Hydroxy-Chloroquine on the Risk and Severity of COVID-19 Infection
There is a pandemic in the world by COVID-19. Currently, the pharmacological curative or prophylactic treatments for this infection are not known.
- Trial name
- PREPCOV (NCT04481633)
- Testing
- COVID 19 serology, COVID 19 Self-Questionnaire
- Where
- 12 sites in France
- Volunteers
- 547 people
- Sponsor
- University Hospital, Toulouse
Prader Willi Syndrome
Evaluation of Tolerance, Suckling and Food Intake After Repeated Nasals Administrations of Oxytocin in PWS Infants
The Prader-Willi syndrome (PWS) includes severe neonatal hypotonia with impaired suckling leading to failure to thrive in the most severe cases, subsequently followed by an early onset of morbid obesity with hyperphagia and…
- Trial name
- OTBB2 (NCT02205034)
- Testing
- oxytocin
- Where
- France
- Volunteers
- 18 people
- Sponsor
- University Hospital, Toulouse