Research institution
The University of Texas Health Science Center at San Antonio Clinical Trials
Studies where The University of Texas Health Science Center at San Antonio is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 89Gingival Recession Localized Moderate, Dental Implant
Free Soft Tissue Grafts (FSTG) Using Autograft Palatal Donor Tissue vs. Xenograft Collagen Matrix (Zderm™)
Participant in this study are asked to participate because they have teeth or dental implants that were identified as having very little gum tissue and would benefit from gum tissue graft surgery.
- Trial name
- NCT07713199
- Testing
- Zderm
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Aging, Functional Decline
Validation & Intervention Testing for Aging, Longevity and Healthspan
The study aims to address the gap between lifespan and healthspan (years of life free of age-related diseases and disabilities) by testing whether 2 approved U.S Food and Drug Administration (FDA) medications, dapagliflozin and…
- Trial name
- VITAL-H (NCT07923630)
- Testing
- Dapagliflozin 10Mg Oral Tablet, Semaglutide oral
- Where
- 5 sites in United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Pheochromocytoma, Paraganglioma
Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated Conditions
Pheochromocytomas and paragangliomas are neural crest-derived tumors of the nervous system that are often inherited and genetically heterogeneous.
- Conditions
- Pheochromocytoma, Paraganglioma, Inherited Cancer Syndrome, Associated Conditions
- Trial name
- NCT03160274
- Testing
- Genetic screening
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
PTSD - Post Traumatic Stress Disorder
Advancing Skills Through Consultation, Education, and Novel Technologies
This research study tests strategies to train behavioral health providers in Written Exposure Therapy (WET), an evidence-based treatment for posttraumatic stress disorder (PTSD).
- Trial name
- ASCENT (NCT07707102)
- Testing
- Live workshop, AI-enhanced Web-based training, Consultation video calls
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
CLIFAHDD, Congenital Contractures of the Limbs and Face, Hypotonia, and Developmental Delay
Aprepitant for the Treatment of CLIFAHDD
There are no drug treatments for individuals with Congenital Contractures of the Limb and Face, Hypotonia, and Developmental Delay (CLIFAHDD), an ultra-rare and severe neurodevelopmental disease.
- Conditions
- CLIFAHDD, Congenital Contractures of the Limbs and Face, Hypotonia, and Developmental Delay, NALCN Channelopathy, Ataxia - Other
- Trial name
- NCT07845825
- Testing
- Aprepitant Powder for Oral Suspension
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Breast Cancer Metastatic
Clinical Trial of Avasopasem in Patients With Metastatic Hormone Receptor Positive Breast Cancer With Progression on a CDK 4/6 Inhibitor and Hormonal Therapy
This study aims to evaluate the safety of avasopasem in combination with CDK 4/6 inhibitor and hormonal therapy in women with metastatic hormone receptor positive breast cancer, and to see if the addition of avasopasem improves…
- Trial name
- NCT07137871
- Testing
- Avasopasem
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
End Stage Renal Disease, Fatigue
Bupropion for Fatigue in End-stage Kidney Disease Patients on Hemodialysis
Fatigue is the most common symptom reported by end-stage kidney disease patients on maintenance hemodialysis. Unfortunately, there currently is no medical management for this overwhelming feeling of tiredness.
- Trial name
- BRISK (NCT06609343)
- Testing
- Bupropion Hydrochloride 150 MG
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Chronic Kidney Disease, Sarcopenia
Sarcopenia in Chronic Kidney Disease (CKD) Patients
Sarcopenia, or loss of muscle and strength is common in patients with poor kidney function. Although a high protein diet is generally recommended for sarcopenia, patients with poor kidney function are advised to follow a…
- Trial name
- BOOST_CKD (NCT07437053)
- Testing
- Valine, EEA
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Insulin Stimulated
Genetics of Skeletal Muscle Insulin Resistance
In this study, the investigators will use euglycemic/hyperinsulinemic clamps, longitudinal skeletal muscle biopsies, and single nucleus ribonucleic acid sequencing (RNA-Seq) and assay for transposase-accessible chromatin using…
- Trial name
- NCT07780513
- Testing
- Insulin 80mU/m2*min
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Opioid Use Disorder
Real World Evaluation of the Effectiveness and Implementation of a Digital Health Therapeutic for OUD
The researchers will study the KIOS app, a digital health tool made to help people recovering from opioid addiction take better care of themselves.
- Trial name
- NCT07348796
- Testing
- KIOS App
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Completed, with results posted
All –Hepatocellular Cancer
Sorafenib Induced Autophagy Using Hydroxychloroquine in Hepatocellular Cancer
The PI is studying if sorafenib/hydroxychloroquine (HCQ) will have improved efficacy when compared to sorafenib alone and in patients progressing of sorafenib the addition of HCQ would lead to disease stability in patients with…
- Trial name
- NCT03037437
- Testing
- Sorafenib (SOR), Hydroxychloroquine (HCQ)
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Frailty
Metformin for Preventing Frailty in High-risk Older Adults
Frailty is a geriatric syndrome which leads to poor health outcomes in older adults, such as falls, disability, hospitalization, institutionalization, and death. Due to the dramatic growth in the U.S.
- Trial name
- NCT02570672
- Testing
- Metformin
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
HIV Antibody Positivity
Feasibility of Positive Links for Youth Care Engagement Intervention
A small pilot study to assess feasibility and acceptability of the PL4Y intervention.
- Trial name
- NCT05689515
- Testing
- Mobile health app
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Knee Osteoarthritis
Blood Flow Restriction Training in Individuals Awaiting Total Knee Replacement
The aim is to demonstrate that preoperative exercises (pre-habilitation) using blood-flow restriction training (BFRT) is safe, well tolerated, improves muscle function, decreases functional limitation, and increases physical…
- Trial name
- NCT06111690
- Testing
- Blood Flow Restriction Training (BFRT)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Heart Failure, Type 2 Diabetes Mellitus
Ketones, Muscle Metabolism, and SGLT2 Inhibitors - Protocol 1
To examine the effect of an increase in plasma beta-hydroxy-butyrate (B-OH-B) levels, spanning the physiologic and pharmacologic range (+0.5, +2.0, and +5.0 mmol/L), on: (i) parameters of left ventricular (LV) systolic and…
- Trial name
- Protocol1 (NCT03560323)
- Testing
- Beta-hydroxy-butyrate
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- The University of Texas Health Science Center at San Antonio