Research institution
Technical University of Munich Clinical Trials
Studies where Technical University of Munich is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 43Heart Failure, Coronary Heart Disease (CHD)
Reliability of Multiple-Repetition-Maximum Tests in Patients With Cardiovascular Disease or Risk Factors
Exercise training is a cornerstone in the prevention and rehabilitation of cardiovascular disease. While research has primarily focused on endurance training, resistance training becomes more and more important.
- Conditions
- Heart Failure, Coronary Heart Disease (CHD), Atrial Fibrillation (AF), Diabetes Mellitus
- Trial name
- NCT06796582
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Technical University of Munich
MDD, Severe Depression
Sensation Seeking and TMS Response in TRD
his real-world observational study examines whether sensation-seeking personality traits influence the clinical response to transcranial magnetic stimulation (TMS) in patients with treatment-resistant depression (TRD).
- Conditions
- MDD, Severe Depression, Major Depressive Episode
- Trial name
- NCT07889739
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Technical University of Munich
Obesity (BMI>30)
Resistance Training to Prevent Muscle Loss During Treatment With Tirzepatide
Incretin-based pharmacotherapies induce significant weight loss and represent a paradigm shift in obesity treatment. However, particularly fast weight loss may be accompanied by a significant loss of muscle mass, which is…
- Trial name
- RESIST (NCT07777575)
- Testing
- Dual GIP/GLP-1 Receptor Agonist Tirzepatide, Resistance Training
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Technical University of Munich
Exercise Behavior, Multiple Myeloma
Exercise Phenotyping Prior to Chemotherapy in Newly Diagnosed Multiple Myeloma (MM-Exercise)
MM-Exercise is a prospective, single-centre, observational pilot study of patients with newly diagnosed multiple myeloma who have not yet started chemotherapy and whose resting echocardiogram is unremarkable or only mildly…
- Trial name
- MM-Exercise (NCT07851493)
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Technical University of Munich
HFpEF - Heart Failure With Preserved Ejection Fraction, Atrial Fibrillation
AlEX-DHF: Ablation and Exercise in Diastolic Heart Failure
The investigators analyze the impact of exercise and ablation in patients with symptomatic short-persistent atrial fibrillation (Afib) and heart failure with preserved ejection fraction (HFpEF).
- Trial name
- AlEX-DHF (NCT06650995)
- Testing
- Exercise training
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Technical University of Munich
Childhood Cancer
ADLs at the End of Acute Treatment for Childhood Leukemia and Non-Hodgkin Lymphoma
Reduced activity levels and reduced muscular strength could severely impair the activities of daily living (ADLs) in pediatric leukemia and Non-Hodgkin lymphoma patients.
- Trial name
- NCT05235633
- Testing
- Assessment of the accomplishment regarding Activities of Daily Living at the end of acute treatment
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Technical University of Munich
Major Depressive Disorder (MDD), Depressive Episodes
Effectiveness of Clustered Versus Tapered Repetitive Transcranial Magnetic Stimulation (rTMS) as Maintenance Therapy Following Successful Acute rTMS Treatment in Patients With Depressive Syndrome
The goal of this clinical trial is to compare two maintenance transcranial magnetic stimulation (rTMS) strategies following successful acute theta burst stimulation (TBS) treatment in adults with depressive syndrome.
- Conditions
- Major Depressive Disorder (MDD), Depressive Episodes, Depressive Syndrome
- Trial name
- ERTE (NCT07727005)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Theta Burst Stimulation
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Technical University of Munich
Diagnoses Disease
HEARTBEAT-TROP. Polyethylene Glycol Precipitation to Unmask Macrotroponin
Troponin elevation can, among others, be due to myocardial infarction, acute inflammation or structural heart disease. Formation of macrocomplexes against troponin is an underestimated cause for persistent troponin elevation.
- Trial name
- MACRO-TROP (NCT07726420)
- Testing
- Polyethylene glycol precipitation, Transthoracic echocardiography
- Where
- Germany
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Healthy Volunteers, Muscle Hypertrophy
Glycolytic Phenotype (vLapeak) and Magnitude of Skeletal Muscle Hypertrophy After Resistance Training
The HyperLa study investigates whether a person's "glycolyticness"-the efficiency with which their body uses glycolysis for energy-can predict how much their muscles will grow (hypertrophy) in response to resistance training.
- Conditions
- Healthy Volunteers, Muscle Hypertrophy, Glycolysis, Moderately Trainend
- Trial name
- HyperLa (NCT07721766)
- Testing
- Hypertrophy-focused Resistance Training
- Where
- 8 sites in Finland, Germany and 2 more
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Gait Analysis on Healthy Adults
Comparison of AI-based Smartphone-derived Gait Parameters With the Gold Standard
This monocentric prospective cohort study evaluates the technical agreement between artificial intelligence (AI)-based smartphone-derived gait parameters and an optical motion-capture system as the current technical gold standard…
- Trial name
- NCT07613957
- Testing
- Gait analysis via vicon- and app-system
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Completed, with results posted
All 1Schizophrenia, Schizoaffective Disorder
Efficacy of an Early Antipsychotic Switch in Case of Poor Initial Response to the Treatment of Schizophrenia
The main aim of the trial is to study whether a change of medication in non-responders to a two-weeks antipsychotic drug trial is more effective than continued treatment with the same antipsychotic.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder
- Trial name
- NCT01029769
- Testing
- Olanzapine or amisulpride
- Where
- Germany
- Volunteers
- 350 people
- Sponsor
- Technical University of Munich