Research institution
KK Women's and Children's Hospital Clinical Trials
Studies where KK Women's and Children's Hospital is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 26Acquired Brain Injury Including Stroke, Epilepsy
Cognitive Rehabilitation Using Neurofeedback With Brain-computer Interface
The goal of this clinical trial is to determine whether a Brain-Computer Interface Neurofeedback Training (BCI-NFT) programme can improve cognitive outcomes, and whether electroencephalography (EEG)-based measures can serve as…
- Trial name
- NCT07828496
- Testing
- Brain-computer interface with neurofeedback with 3D game sessions
- Where
- Singapore
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Continuous Glucose Monitoring, Diabetes, Gestational
Early Pregnancy Lifestyle and Glucose Patterns: A Substudy of TOFFFY
The goal of this clinical trial is to examine how daily behavioral patterns in early pregnancy, including sleep, physical activity, and meal timing, influence continuous glucose dynamics and subsequent risk of gestational…
- Conditions
- Continuous Glucose Monitoring, Diabetes, Gestational, Diet During Pregnancy, Meal Time
- Trial name
- NCT07534670
- Testing
- Continuous glucose monitor (CGM), Wrist actigraphy device, AI-based dietary and meal timing logging mobile application
- Where
- Singapore
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Depression, Postpartum
CODEPAD-III (Collaborative Outcomes of DEpression and Pain Associated With Delivery-III)
The childbirth process is associated with increased risk of having depression and persistent pain which may have adverse effects to mothers and their babies.
- Conditions
- Depression, Postpartum, Pain, Mental Health
- Trial name
- CODEPAD-III (NCT07773259)
- Testing
- Collaborative Psychological Model (CPM), Intervention common to both arms, Telephone-based support (Control)
- Volunteers
- 3,470 people
- Sponsor
- KK Women's and Children's Hospital
Burns and Scalds
Nurse Led Aromatherapy
The goal of this trial is to see if aromatherapy in addition to pain medication, will help manage pain in pediatric burn patients during their first burn dressing change.
- Trial name
- NCT07773181
- Testing
- Aromatherapy
- Where
- Singapore
- Volunteers
- 100 people
- Sponsor
- KK Women's and Children's Hospital
Hysterectomy, Chronic Pain
Evaluation of Central Sensitization, Fear-Avoidance, and Pain-Pressure Threshold With Chronic Pain After Hysterectomy
Phase 1 (started in July 2019): Central Sensitization Inventory (CSI), Fear-Avoidance Components Scale (FACS), pain-pressure threshold are factors associated with chronic post-hysterectomy pain (CPHP), but a complete…
- Conditions
- Hysterectomy, Chronic Pain, Central Sensitisation, Anxiety Depression
- Trial name
- EPOCH (NCT04014829)
- Testing
- Pain-Pressure Threshold, Mechanical Temporal Summation, Hospital Anxiety and Depression Scale
- Where
- Singapore
- Volunteers
- 436 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Physical Activity, Health Behavior
The eHealth Integrated Maternal Physical Activity Programme in Prenatal Care Trial (E-IMPACT)
This will be a proof-of-concept randomised control trial (RCT) study, where 100 pregnant women will be recruited in the first trimester of pregnancy and followed-up until delivery. It aims to test these following hypotheses: 1.
- Trial name
- e-IMPACT (NCT07466797)
- Testing
- e-IMPACT programme
- Where
- Singapore
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Gestational Diabetes, Glucose Metabolism Disorders
Continuous Glucose Monitoring Glycemic cHAracterization During Pregnancy
Our study named Integrated Continuous glucose monitoring glycemic cHAracterization during Pregnancy in comparison with oral glucose tolerance test (I-CHAP) aims to establish much needed preliminary evidence in our Asian…
- Conditions
- Gestational Diabetes, Glucose Metabolism Disorders, Metabolic Disease
- Trial name
- I-CHAP (NCT06357728)
- Testing
- Continuous glucose monitoring
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Infection, Sepsis
Early Sepsis Recognition Tool
This study seeks to develop early recognition tools specially designed for children meeting the Phoenix definition and explore implementation science aspects by investigating facilitators and barriers to adopting Phoenix sepsis…
- Trial name
- SORT (NCT07397689)
- Testing
- Application of the Phoenix Sepsis Score
- Where
- 19 sites in China, Hong Kong and 7 more
- Volunteers
- 40,000 people
- Sponsor
- KK Women's and Children's Hospital
Heart Rate Variability, Anxiety
Heart Rate Variability and Music Listening
High anxiety levels may lead to negative outcomes, and previous studies have shown that music listening could reduce periprocedural anxiety and depression.
- Conditions
- Heart Rate Variability, Anxiety, Depression
- Trial name
- NCT06929208
- Testing
- Electrocardiogram (ECG) monitor, Music listening
- Where
- 3 sites in Singapore
- Volunteers
- 120 people
- Sponsor
- KK Women's and Children's Hospital
Quality of Life, Childbirth
Quality of Recovery After Childbirth
In this proposed study, the investigators hope to assess the quality of recovery after delivery in a local population that would take into account physiological and psychological parameters to better understand the recovery…
- Conditions
- Quality of Life, Childbirth, Maternal Health
- Trial name
- NCT04989894
- Where
- Singapore
- Volunteers
- 122 people
- Sponsor
- KK Women's and Children's Hospital
Completed, with results posted
All 1Adolescent Obesity
Mobile Health Intervention to Identify Early Responders to Treatment in Adolescent Obesity
Background: The Expert Committee on the Assessment, Prevention and Treatment of Child and Adolescent Overweight and Obesity recommends a staged based approach to the management of adolescents with overweight and obesity from…
- Trial name
- NCT03561597
- Testing
- Mobile health intervention
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- KK Women's and Children's Hospital