Research institution
Beth Israel Deaconess Medical Center Clinical Trials
Studies where Beth Israel Deaconess Medical Center is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 79Mild Cognitive Impairment (MCI), Insomnia
Treating Insomnia in Mild Cognitive Impairment
The goal of this study is to test a new way to improve sleep quality in persons living with mild cognitive impairment. The treatment combines a safe and gentle way to stimulate the brain, called transcranial magnetic stimulation…
- Conditions
- Mild Cognitive Impairment (MCI), Insomnia, Subjective Cognitive Decline (SCD)
- Trial name
- NCT06687161
- Testing
- Transcranial Magnetic Stimulation (TMS) therapy, Cognitive behavioral therapy for insomnia (CBT-I)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Beth Israel Deaconess Medical Center
Workplace Wellbeing
Primed to Thrive: Investigating the Combined Impact of Mindfulness Education and Meditation Practice on Psychological and Workplace Outcomes
Employees commonly experience stress and reduced well-being that can affect workplace functioning. This interventional study will evaluate whether combining mindfulness-related educational materials with a brief daily guided…
- Trial name
- BEGIN III (NCT07534683)
- Testing
- Meditation, Mindful Educational Material
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Hip Fractures (ICD-10 72.01-72.2), Post Operative Analgesia
Suzetrigine (Journavx) as Multimodal Therapy for Pain Management in Adults Undergoing Surgery for Hip Fracture
The goal of this clinical trial is to learn whether suzetrigine (Journavx®), when added to standard multimodal pain management, can reduce opioid use while providing adequate pain control in adults undergoing surgery for an acute…
- Trial name
- STRIDE-HIP (NCT07905404)
- Testing
- Suzetrigine (Journavx)
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Beth Israel Deaconess Medical Center
Healthy
Meditation and Yogic Breathing-driven Modulation of Neurofluid Coupling and Brain Clearance
This study will examine whether meditation and yogic breathing can alter brain fluid movement and waste clearance in healthy adults.
- Trial name
- SPANDHA (NCT07903688)
- Testing
- Nadi Shuddhi, Shoonya Meditation
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Robotic Surgery
Perioperative High-flow Nasal Oxygen in Patients Undergoing Robotic Surgery
The aim of the study is to assess whether perioperative use of high-flow nasal oxygen (HFNO) during the period from induction of anesthesia until discharge from the post-anesthesia care unit in patients undergoing…
- Trial name
- Periop HFNO (NCT07591610)
- Testing
- High flow nasal oxygen
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- Beth Israel Deaconess Medical Center
History Taking, Artificial Intelligence (AI)
Safety, Feasibility, and Acceptability of the MINERVA Voice Conversational Agent for Emergency Department History-Taking
This study evaluates whether an artificial intelligence (AI) conversational agent called MINERVA (Medical Interface for Navigating the Emergency Room with Voice Assistance) can safely and feasibly gather medical histories from…
- Trial name
- MINERVA-HX (NCT07877883)
- Testing
- MINERVA AI Chatbot
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Beth Israel Deaconess Medical Center
Neurotoxicity, Neurotoxicity Syndromes
Assessing DCog Short for Neurotoxicity in CAR-T
The aim of this study is to determine the effectiveness of DCog Short, a self-reporting, iPad-based application tool, in assessing neurotoxicity in participants undergoing CAR-T cell therapy.
- Conditions
- Neurotoxicity, Neurotoxicity Syndromes, Hematologic Malignancy, Immune Effector Cell Associated Neurotoxicity Syndrome
- Trial name
- NCT07403812
- Testing
- DCog Short
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Beth Israel Deaconess Medical Center
Labor Pain and to Reduce Pain
Does the Volume of Medication Affect the Success of Labor Epidural Analgesia
The purpose of this study is to evaluate whether changing the volume and concentration of a medication affects the quality of pain relief and the side effects associated with labor epidural analgesia.
- Trial name
- EpiVol (NCT07684365)
- Testing
- administration of bupivacaine 7.5 mg and fentanyl 24 mcg every 40 minutes
- Volunteers
- 70 people
- Sponsor
- Beth Israel Deaconess Medical Center
Perioperative/Postoperative Complications, Postoperative Cognitive Dysfunction
CEReBral AutorEgulation in Non-cardiac SuRgery and Relationship to Postoperative DeliriUm State
The goal of this observational study is to learn the how to determine the mean arterial pressure(MAP) or blood pressure level to be maintained during non-cardiac surgery for optimal brain health in patients above the age of 60…
- Conditions
- Perioperative/Postoperative Complications, Postoperative Cognitive Dysfunction, Postoperative Delirium, EEG With Periodic Abnormalities
- Trial name
- CERBERUS (NCT06133842)
- Testing
- Intra-op EEG and CO data collection
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Chronic Obstructive Pulmonary Disease, Chronic Heart Failure
Mindful Steps 2.0: Promoting Physical Activity in Patients With COPD and HF
The goal of this fully-remote randomized controlled trial is to test the efficacy of Mindful Steps in facilitating physical activity compared to usual standard of care among 136 patients with COPD and/or HF.
- Trial name
- NCT05934565
- Testing
- Mindful Steps
- Where
- 2 sites in United States
- Volunteers
- 136 people
- Sponsor
- Beth Israel Deaconess Medical Center
Completed, with results posted
All 133Ovarian Cancer
Pilot Study of Rosuvastatin and Enoxaparin Thromboprophylaxis Following Ovarian Cancer Surgery (O-STAT Study)
This research study is studying a combination of two drug interventions called rosuvastatin and enoxaparin as a possible preventative measure against developing venous blood clots (such deep vein thrombosis or pulmonary…
- Trial name
- NCT03532139
- Testing
- Enoxaparin, Enoxaparin + Rosuvastatin, Thromboprophylaxis
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Beth Israel Deaconess Medical Center
Keloid
Study to Assess Efficacy and Safety of Dupilumab in the Treatment of Keloids
The study investigates the efficacy and safety of dupilumab in the treatment of keloids
- Trial name
- NCT05128383
- Testing
- Dupilumab
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Beth Israel Deaconess Medical Center
SCHIZOPHRENIA 1 (Disorder), Nicotine Use
Behavioral Impact and Neural Correlates of Network-based Brain Stimulation in Schizophrenia
The primary aims of this study are to investigate the behavioral effects of applying targeted transcranial magnetic stimulation (TMS) to a node of the brain network subserving attention in schizophrenia and schizoaffective…
- Trial name
- NCT07190352
- Testing
- iTBS to the DMN, cTBS to the DMN
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Beth Israel Deaconess Medical Center
Renal Cancer
Vaccination of Patients With Renal Cell Cancer With Dendritic Cell Tumor Fusions and GM-CSF
The main purpose of this study is to test the safety of the dendritic cell/tumor fusion study vaccine in combination with a laboratory-made agent called Granulocyte Macrophage Colony Stimulating Factor (GM-CSF).
- Trial name
- NCT00458536
- Testing
- Dendritic Cell Tumor Fusion Vaccine, Granulocyte Macrophage Colony Stimulating Factor (GM-CSF)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Beth Israel Deaconess Medical Center
Acute Myelogenous Leukemia, AML
Blockade of PD-1 in Conjunction With the Dendritic Cell/AML Vaccine Following Chemotherapy Induced Remission
Acute myelogenous leukemia (AML) arises from leukemia stem cells that are difficult to eradicate and serve as a reservoir for disease relapse following chemotherapy.
- Trial name
- NCT01096602
- Testing
- DC AML Vaccine
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Beth Israel Deaconess Medical Center