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Drug or intervention

Transcranial Magnetic Stimulation Clinical Trials

Studies that test Transcranial Magnetic Stimulation, alone, with other treatments or as the comparison.

2,628 registered studies

In numbers

Open to volunteers
729
Active
811
With results posted
342
All registered
2,628

Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.

Open to volunteers

All 729
  • Anxiety Disorders

    Modulating Escape Using Focused Ultrasound

    • Recruiting
    • Age: 18 to 65 years
    • Medical device

    This is a study to find out if a cutting-edge technology called transcranial focused ultrasound (tFUS) can be used to treat how people with anxiety or related concerns cope with emotional situations.

    Trial name
    NCT06273904
    Testing
    Active transcranial focused ultrasound (tFUS)
    Where
    United States
    Volunteers
    40 people
    Sponsor
    Medical University of South Carolina
    Can I take part? NCT06273904
  • Traumatic Brain Injury

    Assessment of Traumatic Brain Injury Using Transcranial Magnetic Stimulated Evoked Potentials

    • Enrolling by invitation
    • Age: 18 years and older
    • Observational study
    • Medical device

    Patients evaluated at Penn Presbyterian Medical Center for traumatic brain injury (TBI), who sign the informed consent, will undergo assessment of electrophysiologic potentials evoked by transcranial magnetic stimulation (TMS)…

    Trial name
    (TMS-EEG) (NCT06963775)
    Testing
    Delphi-MD device (QuantalX Neuroscience Ltd., Saba Israel)
    Where
    United States
    Volunteers
    215 people, healthy volunteers welcome
    Sponsor
    Ramon Diaz-Arrastia
    Can I take part? (TMS-EEG)
  • Healthy Volunteers

    Phase I Trial of High-Density Theta Burst Stimulation (hdTBS)

    • Not yet recruiting
    • Age: 22 to 60 years
    • Phase 1
    • Medical device

    Background: Transcranial magnetic stimulation (TMS) uses magnetic pulses to affect brain activity. A type of TMS called theta burst stimulation (TBS) is approved to treat people with major depression.

    Trial name
    NCT06868914
    Testing
    TMS (MagVenture MagPro 100 with MagOption)
    Where
    2 sites in United States
    Volunteers
    40 people
    Sponsor
    National Institute on Drug Abuse (NIDA)
    Can I take part? NCT06868914
  • PTSD, PTSD - Post Traumatic Stress Disorder

    Assessing of Behavioral Risk and Response to Electromagnetic and Psychedelic Therapies

    • Not yet recruiting
    • Age: 18 to 69 years
    • Phase 2
    • Medical device
    • Lifestyle or therapy programme

    PRE-EMPT will assemble a cohort of 150 participants from three populations (low risk, intermediate risk, and high risk for self-harm).

    Conditions
    PTSD, PTSD - Post Traumatic Stress Disorder, Major Depression, Suicidality
    Trial name
    PRE-EMPT (NCT07745569)
    Testing
    Transcranial Magnetic Stimulation, Psilocybin (drug), Neurofeedback
    Volunteers
    150 people
    Sponsor
    University of New Mexico
    Can I take part? PRE-EMPT
  • Major Depression

    Single Day of Ultra-accelerated TMS With a Single Dose of NRX-101

    • Recruiting
    • Age: 18 years and older
    • Early Phase 1
    • Medical device

    In this pilot study, investigators aim to combine D-cycloserine, lurasidone, and single-day repeated intermittent Theta Burst Stimulation (iTBS) to preliminarily assess clinical improvement in an open-label cohort and monitor for…

    Trial name
    SPARC-LI (NCT07785102)
    Testing
    TMS, NRX-101
    Where
    United States
    Volunteers
    30 people
    Sponsor
    Mclean Hospital
    Can I take part? SPARC-LI
  • Major Depression, Healthy Participants

    Synaptic Mechanisms of Intermittent Theta Burst Stimulation for Major Depressive Disorder

    • Recruiting
    • Age: 18 years and older
    • Phase 1/2
    • Medical device

    Many people with depression do not get better with standard treatments like medications or talk therapy. Transcranial magnetic stimulation (TMS) is a non-invasive brain stimulation treatment that uses magnetic pulses to stimulate…

    Trial name
    NCT07593222
    Testing
    TMS, D-cycloserine, Dextromethophan
    Where
    United States
    Volunteers
    100 people, healthy volunteers welcome
    Sponsor
    Mclean Hospital
    Can I take part? NCT07593222
  • Healthy Volunteer, Major Depressive Disorder

    Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder

    • Recruiting
    • Age: 18 to 65 years
    • Phase 1
    • Medical device

    Background: Most medications that treat depression take weeks or months to work. Researchers want to develop fast-acting treatments. One dose of ketamine has a rapid antidepressant effect.

    Conditions
    Healthy Volunteer, Major Depressive Disorder, Depression
    Trial name
    NCT03065335
    Testing
    Ketamine, Cobot TS MV robotic arm for TMS, NeurOptics PLRTM-30000 Pupillometer
    Where
    United States
    Volunteers
    150 people, healthy volunteers welcome
    Sponsor
    National Institute of Mental Health (NIMH)
    Can I take part? NCT03065335
  • Parkinson's Disease, Depression

    Efficacy of Repetitive Transcranial Magnetic Stimulation for Improving Depressive Symptoms in Patients With Parkinson's Disease

    • Enrolling by invitation
    • Age: 40 to 90 years
    • Medical device

    The purpose of this study is to evaluate the efficacy of repetitive transcranial magnetic stimulation (rTMS) in improving depressive symptoms in patients with Parkinson's Disease(PD).

    Trial name
    NCT07569133
    Testing
    Repetitive Transcranial Magnetic Stimulation (rTMS)
    Where
    South Korea
    Volunteers
    50 people
    Sponsor
    Ho-Won Lee
    Can I take part? NCT07569133
  • Brain Tumors, Transcranial Magnetic Stimulation

    rTMS for Postoperative Brain Tumor Patients

    • Recruiting
    • Age: 22 to 65 years
    • Medical device

    When doctors perform surgery to remove brain tumors, the goal is to take out as much of the tumor as possible while keeping the patient's brain functions intact.

    Conditions
    Brain Tumors, Transcranial Magnetic Stimulation, Motor Deficit, Quality of Life
    Trial name
    NCT07530536
    Testing
    Transcranial magnetic stimulation (TMS)
    Where
    United States
    Volunteers
    6 people
    Sponsor
    Brian J.Gill
    Can I take part? NCT07530536
  • Auditory Verbal Hallucinations, Schizophrenia

    Theta-Burst Transcranial Magnetic Stimulation for Treatment-Resistant Auditory Hallucinations

    • Recruiting
    • Age: 18 years and older
    • Medical device

    The goal of this clinical trial is to learn whether theta-burst transcranial magnetic stimulation (TBS), a non-invasive brain stimulation technique, can help reduce persistent auditory verbal hallucinations (hearing voices) in…

    Conditions
    Auditory Verbal Hallucinations, Schizophrenia, Schizoaffective Disorder, Psychotic Disorders
    Trial name
    NCT07902518
    Testing
    Theta-Burst Transcranial Magnetic Stimulation (TBS)
    Where
    Canada
    Volunteers
    12 people
    Sponsor
    Ciusss de L'Est de l'Île de Montréal
    Can I take part? NCT07902518

Completed, with results posted

All 279
  • Mild Cognitive Impairment

    Network-guided TMS in Early Alzheimer's Disease

    • Completed
    • Age: 60 to 82 years
    • Medical device
    • Results posted

    The proposed research will test a novel network-based neurostimulation approach using MRI-derived measures of brain connectivity to establish target sites for neurostimulation and test for the enhancement of memory function…

    Trial name
    NetTMS (NCT04549155)
    Testing
    Transcranial Magnetic Stimulation
    Where
    United States
    Volunteers
    37 people, healthy volunteers welcome
    Sponsor
    Duke University
    Can I take part? NetTMS
  • Healthy

    State Dependence of Prefrontal Transcranial Magnetic Stimulation

    • Completed
    • Age: 18 to 65 years
    • Phase 4
    • Medical device
    • Results posted

    The study will examine whether the benefits of brain stimulation on mental functioning can be enhanced if an individual is actively engaging the target brain networks while receiving brain stimulation.

    Trial name
    NCT05962385
    Testing
    Brain state while receiving TMS
    Where
    United States
    Volunteers
    51 people, healthy volunteers welcome
    Sponsor
    University of Minnesota
  • Depression

    Treatment, Emotion, and Neuromodulation of Depression (TREND) Study

    • Completed
    • Age: 18 to 26 years
    • Medical device
    • Results posted

    The investigators will administer theta burst stimulation (TBS) in efforts to observe a decrease in severity of reported depression symptoms. A subset of participants will receive positive affect training during this intervention.

    Trial name
    TREND (NCT05436379)
    Testing
    Theta Burst Stimulation
    Where
    United States
    Volunteers
    21 people
    Sponsor
    Erika Forbes
    Can I take part? TREND
  • Healthy

    Characterizing the Scalp Tolerability of TMS

    • Completed
    • Age: 18 years and older
    • Medical device
    • Results posted

    The primary objective is to characterize the tolerability of TMS by scalp location (over parietal, motor, modified Beam F3 prefrontal, THREE-D prefrontal, orbitofrontal, and medial prefrontal) and stimulation parameters (single…

    Trial name
    NCT06354686
    Testing
    TMS Tolerability
    Where
    United States
    Volunteers
    20 people, healthy volunteers welcome
    Sponsor
    Florida State University
    Can I take part? NCT06354686
  • Stroke

    Phase-dependent Evaluation of Motor Cortex Excitability With TMS in Stroke

    • Completed
    • Age: 18 years and older
    • Medical device
    • Results posted

    The purpose of this study is to investigate the effects of transcranial magnetic stimulation (TMS) on motor cortex excitability in individuals who have suffered stroke and to study the influence of the phase of the oscillatory…

    Trial name
    NCT04968743
    Testing
    Transcranial magnetic stimulation (TMS)
    Where
    United States
    Volunteers
    24 people, healthy volunteers welcome
    Sponsor
    University of Minnesota
    Can I take part? NCT04968743

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