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Drug or intervention

Transcranial Direct Current Stimulation Clinical Trials

Studies that test Transcranial Direct Current Stimulation, alone, with other treatments or as the comparison.

2,154 registered studies

In numbers

Open to volunteers
448
Active
519
With results posted
288
All registered
2,154

Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.

Open to volunteers

All 448
  • Cyberaggression

    Effects of Transcranial Direct Current Stimulation on Cyberaggressive Behaviour in Adults

    • Not yet recruiting
    • Age: 18 years and older
    • Medical device

    This study examines whether transcranial direct current stimulation (tDCS), a non-invasive form of brain stimulation, influences cyberaggressive behaviour in adults.

    Trial name
    NCT07908862
    Testing
    Anodal transcranial direct current stimulation, Cathodal transcranial direct current stimulation
    Where
    Singapore
    Volunteers
    159 people, healthy volunteers welcome
    Sponsor
    Nanyang Technological University
  • Spinal Cord Injury

    Influence of Transcranial Electrical Stimulation on Arm and Hand Function After Cervical Spinal Cord Injury

    • Not yet recruiting
    • Age: 18 years and older

    The goal of this pilot study is to find out how four different types of transcranial electrical stimulation (tES) affect brain activity, the process of acquiring new skills (also called motor learning), and hand function after…

    Trial name
    NCT07909317
    Testing
    transcranial direct current stimulation (tDCS) + FTP, transcranial pulsed current stimulation (tPCS) + FTP, transcranial random noise stimulation (tRNS) + FTP
    Where
    United States
    Volunteers
    12 people
    Sponsor
    Shepherd Center, Atlanta GA
  • Epilepsy

    Lily's Grace Temporal Interference

    • Not yet recruiting
    • Age: 18 to 75 years
    • Medical device

    This study is to evaluate the effectiveness of targeted Transcranial Electrical Stimulation with Temporal Interference (TES-TI) interventions to boost Non-Rapid Eye Movement (NREM) sleep, decrease seizures and promote emotional…

    Trial name
    SLEEP-TIES (NCT07520955)
    Testing
    TES-TI, Structural and Functional MRI
    Where
    United States
    Volunteers
    24 people
    Sponsor
    University of Wisconsin, Madison
    Can I take part? SLEEP-TIES
  • Autism Spectrum Disorder

    Cerebellar Transcranial Direct Current Stimulation (tDCS) in Children With Autism Spectrum Disorder: Raynor Cerebellum Project

    • Recruiting
    • Age: 5 to 21 years
    • Medical device

    The purpose of this research study is to investigate the effects of transcranial direct current stimulation (tDCS) on some of the challenges faced by children with Autism Spectrum Disorder (ASD).

    Trial name
    NCT05691283
    Testing
    trans cranial direct current stimulation (tDCS)
    Where
    United States
    Volunteers
    60 people
    Sponsor
    University of Texas Southwestern Medical Center
    Can I take part? NCT05691283
  • Alcohol Use Disorder, Addiction

    Tdcs And cogNitive traininG cOmbined for AUD (TANGO)

    • Recruiting
    • Age: 18 to 65 years
    • Medical device
    • Lifestyle or therapy programme

    The overarching goal of this project is to expand the traditional expertise in non-invasive neuromodulation at the University of Minnesota towards developing novel paired-neuromodulation approaches using transcranial direct…

    Trial name
    NCT05062369
    Testing
    TaskFlow Transcranial Electrical Stimulation device, Executive Function Focused Cognitive Training
    Where
    United States
    Volunteers
    100 people
    Sponsor
    University of Minnesota
    Can I take part? NCT05062369
  • Anorexia Nervosa

    Cerebellar tDCS Stimulation in Children and Adult Women With Anorexia Nervosa Disorder

    • Recruiting
    • Age: 15 to 30 years
    • Medical device

    Hypothesis: Will the use of tDCS brain modulation in the cerebellum assist in restricted behaviors, social cognition and cognitive flexibility in women with anorexia nervosa in addition to other therapies? Primary Outcomes: 1.

    Trial name
    NCT06286930
    Testing
    anodal trans cranial direct current stimulation (tDCS), cathodal trans cranial direct current stimulation (tDCS)
    Where
    United States
    Volunteers
    15 people
    Sponsor
    University of Texas Southwestern Medical Center
    Can I take part? NCT06286930
  • Parkinson Disease, Mild Cognitive Impairment

    Non-invasive Brain Stimulation for the Treatment of Mild Cognitive Impairment in Parkinson's Disease

    • Recruiting
    • Age: All ages
    • Medical device

    This cross-over pilot study aims to study the acceptability of two methods of non-invasive brain stimulation for the treatment of Parkinson's disease mild cognitive impairment (PD-MCI) - repetitive transcranial magnetic…

    Trial name
    NESCIO-PD (NCT06399731)
    Testing
    High-frequency (10Hz) rTMS, Anodal tDCS
    Where
    Netherlands
    Volunteers
    20 people
    Sponsor
    Amsterdam UMC
    Can I take part? NESCIO-PD
  • Schizophrenia, Working Memory

    tACS for Working Memory in Schizophrenia

    • Recruiting
    • Age: 18 to 50 years
    • Medical device

    This study is a randomized, single-blind, sham-controlled crossover trial enrolling 30 schizophrenia patients, each receiving one active and one sham tACS session (7-day washout), targeting P3/P4 at individual alpha frequency…

    Trial name
    NCT07701343
    Testing
    transcranial alternating current stimulation
    Where
    China
    Volunteers
    30 people
    Sponsor
    Central South University
    Can I take part? NCT07701343
  • Apathy, Brain Stimulation

    Network-based tDCS for Apathy

    • Not yet recruiting
    • Age: 65 years and older
    • Medical device

    Apathy is one of the most common and undertreated neurobehavioral symptoms in older adults with dementia. It is associated with reduced motivation and engagement in daily activities, and may contribute to faster cognitive and…

    Conditions
    Apathy, Brain Stimulation, Dementia
    Trial name
    NCT07900191
    Testing
    transcranial direct current stimulation
    Volunteers
    20 people
    Sponsor
    Hebrew SeniorLife
    Can I take part? NCT07900191
  • Adolescent, Bipolar Depression

    HD-tDCS for Adolescent Bipolar Depression Targeting S1

    • Recruiting
    • Age: 12 to 18 years
    • Medical device

    This randomized, double-blind, sham-controlled clinical trial aims to evaluate the efficacy and underlying biological mechanisms of HD-tDCS targeting the primary somatosensory cortex in adolescents with bipolar depression.

    Conditions
    Adolescent, Bipolar Depression, tDCS, Primary Somatosensory Cortex
    Trial name
    NCT07246044
    Testing
    Active HD-tDCS, Antipsychotics, mood stabilizers, etc.
    Where
    China
    Volunteers
    100 people
    Sponsor
    Jiangsu Province Nanjing Brain Hospital
    Can I take part? NCT07246044

Completed, with results posted

All 238
  • Working Memory

    Non-Invasive Brain Stimulation to Control Large-Scale Brain Networks

    • Completed
    • Age: 18 years and older
    • Medical device
    • Results posted

    This project will assess the feasibility of traveling wave transcranial alternating current stimulation (tACS) to modify working memory performance and large-scale brain connectivity in surgical epilepsy patients.

    Trial name
    NCT04680481
    Testing
    Transcranial alternating current stimulation
    Where
    United States
    Volunteers
    11 people
    Sponsor
    University of Minnesota
    Can I take part? NCT04680481
  • Acute Lymphoblastic Leukemia

    Neurostimulation In Adult Survivors of Childhood Acute Lymphoblastic Leukemia (ALL)

    • Completed
    • Age: 18 to 39 years
    • Medical device
    • Results posted

    Long-term survivors of ALL are at-risk for neurocognitive impairment, particularly in the area of executive functioning. Relatively limited research has focused on interventions for improving neurocognitive outcomes in long-term…

    Trial name
    NCT04007601
    Testing
    Active tDCS
    Where
    United States
    Volunteers
    127 people
    Sponsor
    St. Jude Children's Research Hospital
    Can I take part? NCT04007601
  • Primary Progressive Aphasia

    Treating Primary Progressive Aphasia (PPA) Using High-definition tDCS

    • Completed
    • Age: 45 to 80 years
    • Phase 2
    • Medical device
    • Lifestyle or therapy programme
    • Results posted

    This is a double-blind, sham-controlled, crossover study in which subjects with the non-fluent/agrammatic and logopenic variants of primary progressive aphasia (naPPA and lvPPA, respectively) will undergo language testing and…

    Trial name
    NCT04046991
    Testing
    high-definition transcranial direct current stimulation, modified constraint-induced language therapy
    Where
    United States
    Volunteers
    76 people
    Sponsor
    University of Pennsylvania
    Can I take part? NCT04046991
  • Aging, Depression

    Cognitive Enhancement in Depression (The COG-D Study)

    • Completed
    • Age: 60 years and older
    • Medical device
    • Lifestyle or therapy programme
    • Results posted

    This study will investigate whether transcranial direct current stimulation (tDCS) enhances the effects of computerized cognitive training in older adults with recurrent depression (2 or more lifetime episodes; either current or…

    Conditions
    Aging, Depression, Cognitive Symptom
    Trial name
    NCT05400512
    Testing
    Cognitive Training, tDCS (active stimulation)
    Where
    United States
    Volunteers
    16 people
    Sponsor
    Vanderbilt University Medical Center
  • Obsessive-Compulsive Disorder

    Transcranial Direct Current Stimulation Potentiation of Fear Extinction in OCD

    • Completed
    • Age: 18 to 60 years
    • Medical device
    • Results posted

    The investigators want to learn more about how human beings learn not to fear and the impact of changing the fear network in the brain using transcranial Direct Current Stimulation (tDCS) in individuals with obsessive compulsive…

    Trial name
    NCT05521074
    Testing
    Active tDCS
    Where
    United States
    Volunteers
    86 people
    Sponsor
    Massachusetts General Hospital

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