Drug or intervention
Routine care Clinical Trials
Studies that test Routine care, alone, with other treatments or as the comparison.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 202Renal Cell Carcinoma, Urothelial Carcinoma
Registry Platform Urologic Cancer
The purpose of the project is to set up a national, prospective, longitudinal, multicenter cohort study with associated satellites, a tumor registry platform, to document uniform data on characteristics, molecular diagnostics…
- Trial name
- CARAT (NCT03374267)
- Testing
- Routine care as per site standard.
- Where
- Germany
- Volunteers
- 2,230 people
- Sponsor
- iOMEDICO AG
Prematurity, Feeding Behaviors
Effects of Environmental Comfort and Oral Motor Stimulation on Comfort and Oral Feeding Readiness in Preterm Infants
This study aims to evaluate the effects of short-term environmental comfort interventions and oral motor stimulation on comfort and oral feeding readiness in preterm infants.
- Trial name
- NCT07917871
- Testing
- Massage, White Noise, Oral Motor Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Marmara University
Intensive Care Unit Acquired Weakness
Blood Flow Restriction Training for Mechanically Ventilated Patients With ICU-Acquired Weakness
Patients receiving mechanical ventilation in the intensive care unit (ICU) frequently develop ICU-acquired weakness - a condition marked by widespread muscle loss and weakness caused by prolonged bed rest, severe illness, and…
- Trial name
- BFRT-ICU (NCT07802743)
- Testing
- Blood flow restriction training, Standard ICU Care and Routine Rehabilitation
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Affiliated Hospital of Jining Medical University
Breast Neoplasm Malignant Primary, Lymphedema Arm
Agentic AI App and Home Bioimpedance Monitoring for Endocrine Therapy Adherence and Lymphedema in Breast Cancer Survivors
As survival rates following breast cancer surgery continue to improve, long-term survivorship management has emerged as a crucial clinical priority.
- Conditions
- Breast Neoplasm Malignant Primary, Lymphedema Arm, Medication Adherence, Ductal Carcinoma In Situ
- Trial name
- Pinkmate (NCT07911839)
- Testing
- Cohort1: Pinkmate Agentic AI-ePRO Active Management Platform, Cohort1: Pinkmate Basic Medication Reminders and Standard Outpatient Care, Cohort2: InBody BWA ON Home Bioimpedance Monitoring and Behavioral App
- Where
- South Korea
- Volunteers
- 264 people
- Sponsor
- Chang-Ik Yoon
Chronic Coronary Syndrome
Out-Patient Proactive Observation With Wearable-Assisted Tracking for Cardiovascular Health Management
The goal of this randomized controlled study is to evaluate whether a wearable device-based, Life's Essential 8 (LE8)-guided management strategy can improve cardiovascular health in patients with chronic coronary syndrome (CCS).
- Trial name
- OPPO-WATCH (NCT07912671)
- Testing
- Wearable Device-Based Monitoring and LE8 Feedback, Routine Outpatient Care With Data-Blinded Wearable Monitoring
- Where
- China
- Volunteers
- 400 people
- Sponsor
- China National Center for Cardiovascular Diseases
Breastfeeding Rates
Development and Implementation of a Breastfeeding Program for Post-Cesarean Section Women Based on the 5A Nursing Model
Develop and apply a breastfeeding program for postoperative mothers of cesarean section based on the 5A nursing model, and evaluate its impact on the mothers' mastery of breastfeeding knowledge, self-efficacy, breastfeeding rate…
- Trial name
- NCT07913438
- Testing
- Based on the 5A nursing intervention plan, Implement routine care
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Depressive Symptoms, Perinatal Loss
e-Perinatal Butterfly: An Embedded Study for Parents Experiencing Perinatal Loss
This study is part of the e-Perinatal project and is embedded within the parent e-Perinatal cluster randomized controlled trial (NCT07613008). No additional randomization is performed for this embedded study.
- Conditions
- Depressive Symptoms, Perinatal Loss, Perinatal Grief, Anxiety Symptoms
- Trial name
- e-Butterfly (NCT07898176)
- Testing
- e-Perinatal Butterfly, Standard routine maternal care
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Seville
HIV, HIV - Human Immunodeficiency Virus
Bwelela Easy Study
Treatment interruption in HIV care is one of the most enduring challenges to HIV programs globally and is associated with high rates of detectable virus in the blood and overall morbidity and mortality.
- Conditions
- HIV, HIV - Human Immunodeficiency Virus, Treatment Interruption, Reengagement
- Trial name
- NCT07900750
- Testing
- Standard of Care - Routine Phone Outreach / Standard of Care - Routine Care and Counseling (SOC-RPO/SOC-RCC), Standard of Care - Routine Phone Outreach / Navigation (SOC-RPO/NAV), Standard of Care - Routine Phone Outreach / Navigation plus Community-Based Medication Delivery (SOC-RPO/NAV+CB-Med)
- Where
- Zambia
- Volunteers
- 1,500 people
- Sponsor
- Washington University School of Medicine
Hepatic Encephalopathy, Liver Cirrhosis
Effect of Mini-Program Monitoring on Hepatic Encephalopathy in Post-TIPS Patients
This study is a prospective, multicenter, randomized controlled clinical trial. It aims to evaluate whether an early monitoring and warning system based on a smartphone mini-program can effectively reduce the incidence of overt…
- Trial name
- NCT07901556
- Testing
- Standard Care and Routine Follow-Up, Hepatic Encephalopathy Intelligent Monitoring Mini-Program
- Volunteers
- 394 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Adolescent Idiopathic Scoliosis (AIS)
Protocol for a Randomized Controlled Trial of a Clinician-Supervised Home-School-Hospital-Linked Digital Health Platform-Supported Conservative Management Pathway for AIS
Adolescent idiopathic scoliosis (AIS) brings substantial physical and psychological burden to affected teenagers, and current conservative follow-up management is fragmented under routine clinical settings.
- Trial name
- NCT06314594
- Testing
- Routine Guideline-Based Conservative Care, Clinician-Supervised, Platform-Assisted Conservative Management
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Hangzhou Medical College
Completed, with results posted
All –Abdominal (ABD) Infection
INSPIRE Trial for Abdominal Infections
The INSPIRE Abdominal Infection Trial is a cluster-randomized controlled trial of HCA Healthcare hospitals comparing routine empiric antibiotic stewardship practices with real-time, precision medicine computerized physician order…
- Trial name
- NCT05423743
- Testing
- Arm 1: Routine Care, Arm 2: INSPIRE Stewardship Bundle for Abdominal Infection
- Where
- 101 sites in United States
- Volunteers
- 198,480 people
- Sponsor
- Harvard Pilgrim Health Care
Skin and Soft Tissue (SST) Infection
INSPIRE Trial for Skin and Soft Tissue Infections
The INSPIRE Skin and Soft Tissue Infection trial is a cluster-randomized controlled trial of HCA Healthcare hospitals comparing routine empiric antibiotic stewardship practices with real-time, precision medicine computerized…
- Trial name
- NCT05423756
- Testing
- Arm 1: Routine Care, Arm 2: INSPIRE Stewardship Bundle for Skin and Soft Tissue Infection
- Where
- 102 sites in United States
- Volunteers
- 118,562 people
- Sponsor
- Harvard Pilgrim Health Care
PreDiabetes
CGM Plus GEM in Prediabetes
This study is designed to look into the effect of a lifestyle management guide called GEM (Glycemic Excursion Minimization) alongside continuous glucose monitoring (CGM) and an activity monitor (FitBit) and the effect this can…
- Trial name
- IMPEDE (NCT05580978)
- Testing
- GEM, Routine Care
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Colorado, Denver
Epilepsy
Bridging the Childhood Epilepsy Treatment Gap in Africa
About half of the world's children with epilepsy do not receive treatment - known as the epilepsy treatment gap - with significantly higher rates (67%-90%) in low- and middle-income countries (LMICs).
- Trial name
- BRIDGE (NCT04290975)
- Testing
- Task-shifting epilepsy care to epilepsy-trained community health workers (CHWs), Enhanced usual care for epilepsy (EUC)
- Where
- 3 sites in Nigeria
- Volunteers
- 1,672 people
- Sponsor
- Vanderbilt University Medical Center
Thyroid Nodules, Thyroid Cancer
AIM2: Adequate Selection of Patients for Thyroid Biopsy: Evaluation of a Shared Decision Making Conversation Aid
There is an epidemic of thyroid cancer that is harmful to patients and the medical system. The study hypothesizes that the use of an electronic conversation aid during clinical visits can help patients and clinicians collaborate.
- Trial name
- NCT04463719
- Testing
- Counseling using the electronic conversation aid, counseling by routine care
- Where
- 2 sites in United States
- Volunteers
- 107 people
- Sponsor
- University of Florida