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Drug or intervention

Cognitive Behavioral Therapy Clinical Trials

Studies that test Cognitive Behavioral Therapy, alone, with other treatments or as the comparison.

8,362 registered studies

In numbers

Open to volunteers
1,575
Active
1,898
With results posted
1,095
All registered
8,362

Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.

Open to volunteers

All 1,575
  • Chronic Insomnia Disorder

    Online Tai Chi Versus Digital CBT-I for Chronic Insomnia

    • Not yet recruiting
    • Age: 18 to 65 years
    • Lifestyle or therapy programme

    This multicenter randomized controlled trial will compare online Tai Chi (OTC) with digital cognitive behavioral therapy for insomnia (dCBT-I) in adults with chronic insomnia disorder.

    Trial name
    NCT07853651
    Testing
    Online Tai Chi, Digital Cognitive Behavioral Therapy for Insomnia
    Where
    China
    Volunteers
    172 people
    Sponsor
    The Third Xiangya Hospital of Central South University
    Can I take part? NCT07853651
  • Anxiety Disorders, Major Depressive Disorder

    Study of Neuro-Cognitive Correlates of Pediatric Anxiety Disorders

    • Recruiting
    • Age: 8 to 65 years
    • Phase 2
    • Lifestyle or therapy programme

    Study Description: This study examines relations between neurocognitive and clinical features of pediatric anxiety disorders. The study uses neuro-cognitive tasks, functional magnetic resonance imaging (fMRI), as well as magneto…

    Trial name
    NCT00018057
    Testing
    Attention Bias Modification Training, Fluoxetine, Cognitive Behavioral Therapy
    Where
    2 sites in United States
    Volunteers
    3,500 people, healthy volunteers welcome
    Sponsor
    National Institute of Mental Health (NIMH)
    Can I take part? NCT00018057
  • Quality of Life

    A Hybrid Effectiveness-Implementation and Cost-Utility Evaluation of a Support Programme for Informal Carers of People With Dementia in Primary Care (EsCuidar2)

    • Not yet recruiting
    • Age: 18 years and older

    The aim of this study is to evaluate whether the School of Caring programme improves quality of life and reduces caregiver burden among informal carers of people living with dementia.

    Trial name
    EsCuidar2 (NCT07861789)
    Testing
    School of Caring Programme
    Where
    Spain
    Volunteers
    200 people
    Sponsor
    Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
    Can I take part? EsCuidar2
  • Post-Traumatic Stress Disorder

    Randomized Trial of Tele Vs. Clinic TF-CBT in Puerto Rico

    • Recruiting
    • Age: 7 to 18 years
    • Lifestyle or therapy programme

    The current study will evaluate TF-CBT delivered via tele-health for youth presenting with trauma symptoms via a randomized controlled trial.

    Trial name
    NCT06332209
    Testing
    Trauma Focused Cognitive Behavioral Therapy
    Where
    United States
    Volunteers
    80 people
    Sponsor
    Medical University of South Carolina
    Can I take part? NCT06332209
  • Irritability, Disruptive Mood Dysregulation Disorder

    Psychotherapy for Irritability in Youth: Comparing Active Treatment to Nonactive Psychoeducation Supportive Psychotherapy

    • Recruiting
    • Age: 8 to 17 years
    • Observational study
    • Lifestyle or therapy programme

    Background: Irritability is defined as proneness to anger that may impair a person's ability to function. It is a common reason for why some children need mental health care.

    Conditions
    Irritability, Disruptive Mood Dysregulation Disorder, Oppositional Defiant Disorder, Attention Deficit Hyperactivity Disorder
    Trial name
    NCT07640802
    Testing
    Psychotherapy
    Where
    United States
    Volunteers
    410 people
    Sponsor
    National Institute of Mental Health (NIMH)
    Can I take part? NCT07640802
  • Anxiety Symptoms, Anxiety Disorders

    TOUCHminds: Help-seeking in Adolescents With Anxiety

    • Recruiting
    • Age: 15 to 19 years
    • Lifestyle or therapy programme

    Adolescents frequently experience clinical and subclinical anxiety symptoms, yet many avoid seeking professional help. While universal interventions exist to promote help-seeking, targeted programs for adolescents with elevated…

    Trial name
    TOUCHminds (NCT07366580)
    Testing
    TOUCHminds - Web-Based Intervention
    Where
    Portugal
    Volunteers
    96 people, healthy volunteers welcome
    Sponsor
    Aveiro University
    Can I take part? TOUCHminds
  • Depression in Adolescence

    Teenthrive 2: Treatments for Improving Mood in Teens

    • Recruiting
    • Age: 12 to 18 years
    • Lifestyle or therapy programme

    In this study, we will conduct a pilot RCT of a yoga-based intervention (YBI) vs. group cognitive-behavioral therapy (gCBT) at two sites. We will recruit 48 adolescent participants each in Columbus, OH and Boston, MA (96 total).

    Trial name
    NCT07475845
    Testing
    Yoga-Based Intervention, group CBT
    Where
    2 sites in United States
    Volunteers
    96 people
    Sponsor
    Butler Hospital
    Can I take part? NCT07475845
  • Cancer, Tobacco Use

    Smoking Cessation in Patients With Cancer

    • Recruiting
    • Age: 18 years and older
    • Lifestyle or therapy programme

    This randomized controlled trial will evaluate whether adding one-session structured cognitive behavioral therapy (CBT)-based smoking-cessation counseling to standardized brief smoking-cessation counseling improves cigarette…

    Trial name
    NCT07822464
    Testing
    Standardized Brief Smoking-Cessation Counseling, Add-on One-Session Structured CBT-Based Smoking-Cessation Counseling
    Where
    Vietnam
    Volunteers
    446 people
    Sponsor
    Nguyen Duc Khoa, MD, PhD
    Can I take part? NCT07822464
  • Borderline Personality Disorder (BPD)

    Combining Transcranial Magnetic Stimulation With Emotion Regulation Skills Training in Borderline Personality Disorder

    • Recruiting
    • Age: 22 to 65 years
    • Medical device
    • Lifestyle or therapy programme

    Impaired emotion regulation is a core feature of borderline personality disorder (BPD) and a known driver of functional impairment, interpersonal difficulties, self-harm, and suicidality.

    Trial name
    NCT07714005
    Testing
    Transcranial Magnetic Stimulation (TMS), Emotion Regulation Skills Training
    Where
    United States
    Volunteers
    12 people
    Sponsor
    Massachusetts General Hospital
    Can I take part? NCT07714005
  • Epilepsy

    An Examination of Cognitive and Sensorimotor Processes in Patients With Epilepsy

    • Enrolling by invitation
    • Age: 5 years and older

    The overall goal of this project is to better understand the micro-physiology of human epilepsy and cognition using the intracranial electroencephalogram (iEEG), electrical brain stimulation, functional magnetic resonance imaging…

    Trial name
    NCT00859794
    Testing
    fMRI, Neuropsychological Testing, Additional electrode implantation
    Where
    United States
    Volunteers
    450 people
    Sponsor
    Northwell Health
    Can I take part? NCT00859794

Completed, with results posted

All 1,034
  • Mild Cognitive Impairment, Adherence, Patient

    MI-CBT Adherence Program for Lifestyle Interventions in Older Adults

    • Completed
    • Age: 60 to 85 years
    • Lifestyle or therapy programme
    • Results posted

    Objective 1: Assess feasibility and acceptability of all protocol components of a pilot trial testing a 6-week telehealth Mediterranean ketogenic nutrition adherence (KNA) program using motivational interviewing and cognitive…

    Conditions
    Mild Cognitive Impairment, Adherence, Patient, Ketosis
    Trial name
    MI-CBT KNAP (NCT04817176)
    Testing
    Motivational Interviewing-Cognitive Behavioral Therapy Ketogenic Nutrition Adherence Program, Ketogenic Nutrition Program
    Where
    United States
    Volunteers
    58 people, healthy volunteers welcome
    Sponsor
    Florida State University
    Can I take part? MI-CBT KNAP
  • Avoidant/Restrictive Food Intake Disorder

    Confirming the Efficacy/Mechanism of Family Therapy for Children With Low Weight ARFID

    • Completed
    • Age: 6 to 12 years
    • Lifestyle or therapy programme
    • Results posted

    This study is examining the efficacy and mechanism of family therapy compared to usual care for children between the ages of 6 and 12 who are diagnosed with Avoidant/Restrictive Food Intake Disorder.

    Trial name
    NCT04450771
    Testing
    Family-based Treatment for ARFID, Manualized Non-Specific Usual Care for ARFID
    Where
    United States
    Volunteers
    285 people
    Sponsor
    Stanford University
    Can I take part? NCT04450771
  • Stress Disorders, Post-Traumatic

    Safety Aid Reduction Treatment for PTSD Among Veterans

    • Completed
    • Age: 18 years and older
    • Lifestyle or therapy programme
    • Results posted

    The purpose of this project is to examine the acceptability, feasibility, and utility of a safety aid reduction treatment (START) among Veterans with posttraumatic stress disorder (PTSD).

    Trial name
    START-PTSD (NCT04515784)
    Testing
    Safety Aid Reduction Treatment for PTSD
    Where
    United States
    Volunteers
    45 people
    Sponsor
    VA Office of Research and Development
    Can I take part? START-PTSD
  • Alcohol

    Decisions During Drinking

    • Completed
    • Age: 18 to 24 years
    • Lifestyle or therapy programme
    • Results posted

    Decisions during drinking (D3) is randomized clinical feasibility trial assessing whether health-related materials created for young adults who want to have more positive experiences if they decide to drink alcohol are acceptable…

    Trial name
    D3 (NCT06978140)
    Testing
    Personalized feedback
    Where
    United States
    Volunteers
    35 people
    Sponsor
    University of Washington
    Can I take part? D3
  • Cancer, Survivorship

    A Dyadic Intervention for Young Adult Patients With Cancer and Their Partner Caregivers

    • Completed
    • Age: 25 to 39 years
    • Lifestyle or therapy programme
    • Results posted

    The purpose of this pilot study is to examine the feasibility and acceptability of a brief psychotherapy intervention to improve psychosocial coping and maintain couple relationships among young adults (aged 25-39) with cancer…

    Conditions
    Cancer, Survivorship, Caregiver Burden, Psychological Distress
    Trial name
    YAD (NCT06172907)
    Testing
    Young Adults Coping with Cancer Together Intervention
    Where
    4 sites in United States
    Volunteers
    20 people
    Sponsor
    Massachusetts General Hospital
    Can I take part? YAD

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