Country
Clinical Trials in Nepal
Studies with at least one site in Nepal. Open a trial for its sites in Nepal, who to contact and who can take part.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 55Chronic Lung Diseases
Prospective Study on Antimicrobial RESIstance in Chronic Pulmonary DiseasE
This observational, multicentric prospective study aims to understand the prevalence and burden of antimicrobial resistance (AMR) in people with chronic lung diseases (CLD) across the globe, understanding also geographical…
- Trial name
- PRESIDE (NCT07874139)
- Where
- 68 sites in United States, Albania and 31 more
- Volunteers
- 683 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Dengue
Emetine for Viral Outbreaks (a.k.a. EVOLVE Antiviral Initiative)
The goal of this study is to evaluate the efficacy and safety of emetine administered orally for symptomatic patients aged 18-65 years infected with the dengue virus. The main questions it aims to answer are: 1.
- Trial name
- NCT07016321
- Testing
- Emetine Hydrochloride 6mg, Emetine Hydrochloride 12mg
- Where
- 2 sites in United States, Nepal
- Volunteers
- 600 people
- Sponsor
- Johns Hopkins University
Spirometry
The INTERvening for LUNG Health Trial
This research study is being done to find out whether a community health volunteer-delivered, multi-component program can improve lung health for people at risk of chronic respiratory diseases (such as asthma or COPD) in…
- Trial name
- INTERLUNG (NCT07540000)
- Testing
- Community health worker-delivered multi-component respiratory health intervention
- Where
- 2 sites in United States, Nepal
- Volunteers
- 800 people
- Sponsor
- Johns Hopkins University
Lower Respiratory Tract Infection (LRTI), Recurrent Wheezing
Prevent Wheeze Trial
This trial investigates whether a single dose of dexamethasone will prevent recurrent wheezing in children at high-risk for asthma admitted to hospital with a lower respiratory tract infection (LRTI).
- Trial name
- PRE-WHEE (NCT07858773)
- Testing
- Dexamethasone 0.6 mg/kilogram body weight single dose
- Where
- 2 sites in Nepal, South Africa
- Volunteers
- 486 people
- Sponsor
- Norwegian University of Science and Technology
Post-Dural Puncture Headache
Effect of Altitude on Postdural Puncture Headache After Caesarean Delivery
The aim of this study is to examine the effects of altitude (high altitude versus low altitude) on incidence and severity of postural puncture headache (PDPH) following spinal anaesthesia for caesarean delivery.
- Trial name
- NCT05804448
- Where
- 2 sites in Nepal
- Volunteers
- 292 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Suicide, Suicide Prevention
Peer Delivered Youth Suicide Prevention in Nepal
South Asia has the highest suicide rate in the world with important risk profile differences from high-income settings. Investigators will conduct formative research to co-design a package of brief interventions and…
- Trial name
- NCT07680179
- Testing
- Enhanced Usual Care (EUC), Youth-focused, Peer-delivered, Family-engaged Suicide Prevention Package (YPF-SuPP)
- Where
- Nepal
- Volunteers
- 160 people
- Sponsor
- Yale University
Bleeding Post-mechanical Valve Replacement, Thromboembolism Post-mechanical Valve Replacement
Low INR to Minimize Bleeding With Mechanical Valves Trial
This study evaluates the use of a lower INR target (1.5 to 2.5) in patients with a mechanical bileaflet heart valve in the aortic position.
- Trial name
- LIMIT (NCT03636295)
- Testing
- Warfarin
- Where
- 45 sites in Belgium, Botswana and 16 more
- Volunteers
- 2,625 people
- Sponsor
- Population Health Research Institute
Mental Health
Effectiveness and Implementation of a School-based Mental Well-being Intervention Among Adolescents of Bharatpur, Nepal
The goal of this study is to evaluate the effectiveness and assess the implementation of CROSS-MIND, a school-based mental well-being intervention for adolescents in Nepal. The study uses a Hybrid Type 1 mixed-methods design.
- Trial name
- CROSSMIND_NP (NCT07812168)
- Testing
- CROSS-MIND
- Where
- Nepal
- Volunteers
- 1,060 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Hypertension, Diabetes
Group-Care for Hypertension and Diabetes Management in Nepal
Hypertension and diabetes represent significant and growing public health challenges in Nepal, particularly in underserved communities.
- Trial name
- GCHD- Nepal (NCT07439380)
- Testing
- Low Intensity Community-Based Group NCD Care, High Intensity Community-Based Group NCD Care
- Where
- Nepal
- Volunteers
- 1,110 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Hip Fractures, Myocardial Injury
HIP Fracture Accelerated Surgical TreaTment And Care tracK 2 Trial
The HIP ATTACK-2 trial is a multicentre, international, parallel group randomized controlled trial to determine whether accelerated surgery for hip fracture in patients with acute myocardial injury is superior to standard care in…
- Trial name
- HIP ATTACK-2 (NCT04743765)
- Testing
- Accelerated medical clearance and surgery
- Where
- 77 sites in United States, Australia and 18 more
- Volunteers
- 1,100 people
- Sponsor
- Population Health Research Institute
Completed, with results posted
All –Mental Disorders
Reducing Stigma Among Healthcare Providers to Improve Mental Health Services
A growing number of trials have demonstrated treatment effectiveness for people with mental illness (PWMI) by non-specialist providers, such as primary care and community health workers, in low-resource settings.
- Trial name
- RESHAPE-mh (NCT02793271)
- Testing
- RESHAPE, PRIME/mhGAP
- Where
- Nepal
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Brandon A Kohrt, MD, PhD
Mitral Valve Disease
PRESERVE-MITRAL Post-Market Registry
The objective of this registry is to gather data on the clinical outcomes of Medtronic mitral repair products (Profile 3D™ and CG Future® annuloplasty systems) in the approved intended use up to 12 months from the day of procedure
- Trial name
- NCT03283722
- Testing
- Profile 3D™ and CG Future® annuloplasty system
- Where
- 12 sites in Bangladesh, India and 1 more
- Volunteers
- 200 people
- Sponsor
- Medtronic Cardiac Surgery
Sickle Cell Disease, Sickle Cell Trait
Evaluation of Low-cost Techniques for Detecting Sickle Cell Disease and β-thalassemia in Nepal and Canada
Sickle cell disease (SCD) is an inherited blood disorder associated with acute illness and organ damage. In high resource settings, early screening and treatment greatly improve quality of life.
- Conditions
- Sickle Cell Disease, Sickle Cell Trait, Beta-Thalassemia, Sickle Cell-Beta Thalassemia
- Trial name
- NCT05506358
- Testing
- High performance liquid chromatography, Automated sickling test, HbS solubility test
- Where
- 3 sites in Canada, Nepal
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Burn Body Region Unspecified, Burn Shock
Enteral Resuscitation Nepal (Pilot Study)
Nepal and the South Asian sub-continent carry some of the highest rates of burn injury globally, with an associated high morbidity and mortality.
- Trial name
- NCT04732624
- Testing
- Oral Rehydration Solution, Lactated Ringer
- Where
- Nepal
- Volunteers
- 30 people
- Sponsor
- University of Washington
Postoperative Pain
Morphine Added to Ropivacaine for FICB for Postoperative Analgesia
prospective, randomized double blinded study to investigate the effects of morphine as an adjuvant to ropivacaine on FICB
- Trial name
- NCT03875274
- Testing
- Ropivacaine, Morphine, Ropivacaine, Saline
- Where
- Nepal
- Volunteers
- 70 people
- Sponsor
- B.P. Koirala Institute of Health Sciences